Company lists · Data refreshed September 2026

Top 25 Drug repurposing companies based in the United States

RevenueBase identified 102 drug repurposing companies headquartered in the United States as of September 2026 and tracks 1,504 professional contacts across them, including 711 with verified work emails. Cambridge is the largest hub.

This list covers drug repurposing companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 19, 2026 86% judged on-target in blind review
102Companies
1,504Contacts tracked
711Verified emails
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The 25 largest drug repurposing companies based in the United States

Ranked by team size
Top 25 of 102 drug repurposing companies based in the United States, ranked by team size, largest first. Data refreshed Sep 19, 2026. RevenueBase Smart Search rates how each company's information relates to drug repurposing companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 19, 202651-200176 contacts →

Indirect evidence

“Structure Therapeutics is a science-driven clinical-stage biopharmaceutical company focused on discovering and developing innovative oral small molecule treatments for chronic…”

Source: RevenueBase Database · checked Sep 19, 2026
2Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 19, 202651-200119 contacts →

Indirect evidence

“Septerna is on a mission to make the promise of future GPCR medicines a reality for patients.”

Source: RevenueBase Database · checked Sep 19, 2026
3Partial evidenceCambridge, MA, United StatesHQ checked Sep 19, 202651-200116 contacts →

Partial evidence

“Pioneering Medicines, Flagship Pioneering’s in house drug discovery and development unit, is dedicated to conceiving and developing a broad portfolio of life-changing treatments…”

Source: RevenueBase Database · checked Sep 19, 2026
4Partial evidenceBoston, MA, United StatesHQ checked Sep 19, 202651-200102 contacts →

Partial evidence

“Nimbus Therapeutics is a clinical-stage, structure-based drug discovery company developing novel small molecule medicines designed to act against well-validated but…”

Source: RevenueBase Database · checked Sep 19, 2026
5Indirect evidenceBoston, MA, United StatesHQ checked Sep 19, 202651-20091 contacts →

Indirect evidence

“Jnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation chemoproteomics RAPID platform to discover medicines for highly validated…”

Source: RevenueBase Database · checked Sep 19, 2026
6Indirect evidenceEast Windsor Township, NJ, United StatesHQ checked Sep 19, 202651-20084 contacts →

Indirect evidence

“Novitium Pharma is a U.S.”

Source: RevenueBase Database · checked Sep 19, 2026
7Indirect evidenceCambridge, MA, United StatesHQ checked Sep 19, 202611-5069 contacts →

Indirect evidence

“Transforming the right molecules into the best medicines™ Boston Pharmaceuticals acquires and transforms innovative molecules into differentiated medicines that improve patients’…”

Source: RevenueBase Database · checked Sep 19, 2026
8Indirect evidenceRockville, MD, United StatesHQ checked Sep 19, 202651-20051 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 19, 2026
9Indirect evidenceBoston, MA, United StatesHQ checked Sep 19, 202611-5044 contacts →

Indirect evidence

“Superluminal Medicines is a Boston-based generative biology and chemistry company developing a differentiated pipeline and revolutionizing the speed and accuracy of how medicine…”

Source: RevenueBase Database · checked Sep 19, 2026
10Indirect evidencePhiladelphia, PA, United StatesHQ checked Sep 19, 202611-5041 contacts →

Indirect evidence

“Every Cure is a nonprofit organization dedicated to unlocking the full potential of every existing medicine to treat every disease possible.”

Source: RevenueBase Database · checked Sep 19, 2026
11Partial evidenceSan Jose, CA, United StatesHQ checked Sep 19, 202611-5028 contacts →

Partial evidence

“BridGene Biosciences is a biotechnology company focused on discovering and developing innovative small molecules that drug high value yet previously undruggable targets, providing…”

Source: RevenueBase Database · checked Sep 19, 2026
12Partial evidenceHamilton, NJ, United StatesHQ checked Sep 19, 202611-5027 contacts →

Partial evidence

“VENENUM Biodesign, a Genesis Drug Discovery and Development (GD3) Company, is focused on discovering and advancing innovative new medicines for significant unmet medical needs in…”

Source: RevenueBase Database · checked Sep 19, 2026
13Partial evidenceLas Vegas, NV, United StatesHQ checked Sep 19, 202611-5027 contacts →

Partial evidence

“GB Sciences, Inc.(OTCQB:GBLX) is a data-driven drug discovery and development company that leverages machine learning and high-throughput biology to transform plant-inspired drug…”

Source: RevenueBase Database · checked Sep 19, 2026
14Indirect evidenceCambridge, MA, United StatesHQ checked Sep 19, 202611-5026 contacts →

Indirect evidence

“Eccogene is focused on building a pipeline of best-in-class small molecule therapeutics for chronic cardiometabolic and inflammatory conditions with the goal of improving care and…”

Source: RevenueBase Database · checked Sep 19, 2026
15Partial evidenceSan Diego, CA, United StatesHQ checked Sep 19, 202611-5024 contacts →

Partial evidence

“Protego Biopharma is a San Diego-based biotech company focused on developing small-molecule drugs that target protein misfolding pathways.”

Source: RevenueBase Database · checked Sep 19, 2026
16Indirect evidenceCincinnati, OH, United StatesHQ checked Sep 19, 202611-5021 contacts →

Indirect evidence

“CinRx Pharma is a biotech company advancing a diverse portfolio of high-impact medicines through clinical development with a unique hub-and-spoke business model.”

Source: RevenueBase Database · checked Sep 19, 2026
17Indirect evidenceBaltimore, MD, United StatesHQ checked Sep 19, 202611-5019 contacts →

Indirect evidence

“Rapafusyn Pharmaceuticals is an emerging pharmaceutical development company located in Baltimore Maryland.”

Source: RevenueBase Database · checked Sep 19, 2026
18Partial evidenceWatertown, MA, United StatesHQ checked Sep 19, 202611-5017 contacts →

Partial evidence

“Nexo therapeutics is a small molecule therapeutics company dedicated to the discovery and development of new drugs for patients who currently lack meaningful therapies.”

Source: RevenueBase Database · checked Sep 19, 2026
19Partial evidenceCharlottesville, VA, United StatesHQ checked Sep 19, 202611-5016 contacts →

Partial evidence

“Adovate develops novel drugs that target adenosine receptors involved in major diseases.”

Source: RevenueBase Database · checked Sep 19, 2026
20Indirect evidenceParsippany-troy Hills, NJ, United StatesHQ checked Sep 19, 202611-5016 contacts →

Indirect evidence

“Validus is focused on acquiring, reformulating, and marketing prescription products in specialty therapeutic areas.”

Source: RevenueBase Database · checked Sep 19, 2026
21Partial evidenceCambridge, MA, United StatesHQ checked Sep 19, 202611-5015 contacts →

Partial evidence

“Exo Therapeutics is a small molecule drug discovery and development company with a pioneering technology to address intractable pharmaceutical targets.”

Source: RevenueBase Database · checked Sep 19, 2026
22Indirect evidenceFremont, CA, United StatesHQ checked Sep 19, 202611-5015 contacts →

Indirect evidence

“Invest in pharmaceutical-grade high-value compounds created by natural biological synthesis at a significantly lower cost than conventional methods.”

Source: RevenueBase Database · checked Sep 19, 2026
23Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 19, 202611-5014 contacts →

Partial evidence

“Leapfrog Bio is a clinical-stage precision oncology company accelerating cancer drug development by identifying clinical-stage molecules that can be retargeted as directed…”

Source: RevenueBase Database · checked Sep 19, 2026
24Partial evidenceCharlottesville, VA, United StatesHQ checked Sep 19, 202611-5011 contacts →

Partial evidence

“HemoShear Therapeutics is a biotechnology company focused on discovering novel biological targets and developing drugs to treat children’s rare metabolic disorders.”

Source: RevenueBase Database · checked Sep 19, 2026
25Partial evidenceRocky Hill, NJ, United StatesHQ checked Sep 19, 20261-109 contacts →

Partial evidence

“Nexomics Biosciences focuses on the discovery, development and commercialization of novel drugs focusing on cancer, antiviral and antibiotic treatments.”

Source: RevenueBase Database · checked Sep 19, 2026

Showing 25 of 102 drug repurposing companies based in the United States

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Drug repurposing companies based in the United States at a glance

As of Sep 19, 2026
47.3%Verified-email coverage
14.7Average contacts per company
1-10Median size (employees)
4.9%Largest-city concentration · Cambridge
Sep 19, 2026Page data refreshed

Companies by employee count

1-10
57
11-50
37
51-200
8

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 102 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among drug repurposing companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “drug repurposing companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names drug repurposing companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among drug repurposing companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 711 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names drug repurposing companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many drug repurposing companies are there based in the United States?

RevenueBase identified 102 drug repurposing companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Structure Therapeutics, headquartered in South San Francisco, tops this list with the largest team on record.

Which city has the most drug repurposing companies?

Cambridge leads with 5 headquartered companies, followed by San Diego (5) and South San Francisco (5).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 711 verified decision-maker contacts tracked across these 102 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.