Company lists · Data refreshed September 2026

Top 25 Drug discovery companies based in the United States

RevenueBase identified 538 company matches for drug discovery companies associated with the United States as of September 2026 and tracks 28,455 professional contacts across them, including 14,089 with verified work emails. San Diego is the largest hub.

This list covers company matches for drug discovery companies associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed September 19, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Sep 19, 2026 How this list was built
538Companies
28,455Contacts tracked
14,089Verified emails
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The 25 largest drug discovery companies based in the United States

Ranked by team size
Top 25 of 538 company matches for drug discovery companies based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Sep 19, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchWilmington, MA, United StatesHQ recorded Sep 19, 202610001+14,166 contacts →

Exact match

“At Charles River, we are guided by our strong purpose-to create healthier lives-which centers around the patients who rely on the therapeutics we help to develop, the animals in…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
2Exact matchPiscataway, NJ, United StatesHQ recorded Sep 19, 20265,001-10,0001,194 contacts →

Exact match

“GenScript Life Science Group is a part of GenScript Biotech Corporation.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
3Exact matchWest Lafayette, IN, United StatesHQ recorded Sep 19, 20261,001-5,0001,015 contacts →

Exact match

“WHERE INSIGHTS LEAD TO ANSWERS Expect More In choosing a partner for discovery, development and research models, expect more: more attention, more insight, and a superlative…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
4Exact matchNew York, NY, United StatesHQ recorded Sep 19, 2026501-1,000957 contacts →

Exact match

“Schrödinger’s industry-leading computational platform facilitates the research efforts of biopharmaceutical and industrial companies, academic institutions, and government…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
5Exact matchPasadena, CA, United StatesHQ recorded Sep 19, 2026501-1,000657 contacts →

Exact match

“Arrowhead Pharmaceuticals is a clinical stage, Nasdaq listed (ticker ARWR) company developing medicines that treat intractable diseases by silencing the genes that cause them.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
6Exact matchThe Woodlands, TX, United StatesHQ recorded Sep 19, 202651-200311 contacts →

Exact match

“Corporate Overview Lexicon Pharmaceuticals is a biopharmaceutical company that has harnessed the power of genetics for drug discovery.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
7Exact matchSan Diego, CA, United StatesHQ recorded Sep 19, 2026201-500273 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
8Exact matchLexington, MA, United StatesHQ recorded Sep 19, 202651-200191 contacts →

Exact match

“Valo is a technology company built to transform drug discovery and development using large-scale data and AI-powered computation.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
9Exact matchHouston, TX, United StatesHQ recorded Sep 19, 20261,001-5,000187 contacts →

Exact match

“Welcome to Selleck Chemicals!”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
10Exact matchWatertown, MA, United StatesHQ recorded Sep 19, 202651-200164 contacts →

Exact match

“Treeline (or Treeline Biosciences) is a privately held, clinical-stage biopharma company that aspires to make medicines at the highest level.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
11Exact matchWaltham, MA, United StatesHQ recorded Sep 19, 2026201-500156 contacts →

Exact match

“X-Chem is your preferred partner for innovative small molecule discovery.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
12Exact matchNewark, CA, United StatesHQ recorded Sep 19, 202651-200136 contacts →

Exact match

“Protagonist Therapeutics (Nasdaq: PTGX) is a biopharmaceutical company with a proprietary technology platform focused on discovering and developing peptide-based new chemical…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
13Exact matchMalvern, PA, United StatesHQ recorded Sep 19, 202651-200133 contacts →

Exact match

“Reaction Biology specializes in answering your complex scientific questions to accelerate the development of your breakthrough therapeutic candidates.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
14Exact matchPasadena, CA, United StatesHQ recorded Sep 19, 202651-200128 contacts →

Exact match

“Terray is a biotechnology company with the technology, data, and mindset to radically change the way we discover and develop small molecule therapeutics.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
15Exact matchSanta Fe, NM, United StatesHQ recorded Sep 19, 202651-200121 contacts →

Exact match

“OpenEye, Cadence Molecular Sciences is an industry leader in computational molecular design based on decades of delivering rapid, robust, and scalable software, toolkits, and…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
16Exact matchSouth San Francisco, CA, United StatesHQ recorded Sep 19, 202651-200119 contacts →

Exact match

“Septerna is on a mission to make the promise of future GPCR medicines a reality for patients.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
17Exact matchCambridge, MA, United StatesHQ recorded Sep 19, 202651-200116 contacts →

Exact match

“Pioneering Medicines, Flagship Pioneering’s in house drug discovery and development unit, is dedicated to conceiving and developing a broad portfolio of life-changing treatments…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
18Exact matchSouth San Francisco, CA, United StatesHQ recorded Sep 19, 202611-50116 contacts →

Exact match

“NGM Bio is a biopharmaceutical company focused on discovering and developing novel, life-changing medicines for people whose health and lives have been disrupted by disease.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
19Exact matchCypress, United StatesHQ recorded Sep 19, 2026201-500106 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
20Exact matchBoston, MA, United StatesHQ recorded Sep 19, 202651-200102 contacts →

Exact match

“Nimbus Therapeutics is a clinical-stage, structure-based drug discovery company developing novel small molecule medicines designed to act against well-validated but…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
21Exact matchWaltham, MA, United StatesHQ recorded Sep 19, 202611-50101 contacts →

Exact match

“At Ventus, we are pioneering a unique approach to structure-based drug discovery to address biologically validated, but difficult-to-drug targets.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
22Exact matchSouth San Francisco, MA, United StatesHQ recorded Sep 19, 202651-20091 contacts →

Exact match

“Frontier Medicines, located in South San Francisco, CA and Boston, MA, is a precision medicine company that has pioneered a powerful discovery and development platform designed to…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
23Exact matchBoston, MA, United StatesHQ recorded Sep 19, 202651-20091 contacts →

Exact match

“Jnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation chemoproteomics RAPID platform to discover medicines for highly validated…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
24Exact matchJupiter, FL, United StatesHQ recorded Sep 19, 202611-5090 contacts →

Exact match

“Ligand is a leading royalty aggregator, partnering with biopharmaceutical companies to finance and advance late-stage clinical development programs.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
25Exact matchBoston, OR, United StatesHQ recorded Sep 19, 202611-5084 contacts →

Exact match

“Drug Hunter™ is reinventing drug discovery intelligence for R&D-focused organizations turning molecules into medicines.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase

Showing 25 of 538 drug discovery companies based in the United States

See the full list, filter by size, metro and specialty, and access 14,089 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Drug discovery companies based in the United States at a glance

As of Sep 19, 2026
49.5%Verified-email coverage
52.9Average contacts per company
11-50Median size (employees)
8.7%Largest-city concentration · San Diego
Sep 19, 2026Page data refreshed

Companies by employee count

1-10
258
11-50
191
51-200
62
201-500
11
501-1,000
7
1,001-5,000
6
5,001-10,000
2
10001+
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 538 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “drug discovery companies” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 14,089 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “drug discovery companies”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many drug discovery companies are there based in the United States?

RevenueBase identified 538 company matches for drug discovery companies associated with the United States as of September 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Charles River Laboratories tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most drug discovery companies?

San Diego leads with 47 company records, followed by Boston (27) and New York (22).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 14,089 professional contacts with verified work emails tracked across these 538 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.