Company lists · Data verified August 2026

Top 25 Drug discovery AI companies based in the United States

There are 850 drug discovery AI companies headquartered in the United States (RevenueBase, August 2026). RevenueBase tracks 26,140 professional contacts across them, including 12,385 with verified work emails and 9,262 with mobile numbers. San Francisco is the largest hub.

This list covers drug discovery AI companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Data current as of August 28, 2026.

850Companies
26,140Contacts tracked
12,385Verified emails
9,262Mobile numbers
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The 25 largest drug discovery AI companies based in the United States

Ranked by team size
Top 25 of 850 drug discovery AI companies based in the United States, ranked by team size, largest first. Data verified Aug 28, 2026. Click a count to unlock that company's people.
#CompanyHQEmployeesContactsVerified emails
1Tempus AIDurham, NC1,001-5,0002,7861,709
2ArisglobalWaltham, MA1,001-5,0001,903476
3SAAMAGlendale, AZ1,001-5,0001,666678
4Caris Life SciencesIrving, TX1,001-5,0001,55137
5CertaraBlue Bell, PA1,001-5,0001,244876
6BenchlingBoston, MA501-1,000841601
7RecursionSalt Lake City, UT501-1,000779515
8BostongeneWaltham, MA501-1,000434223
9Eikon TherapeuticsMillbrae, CA201-500422309
10qure.aiNew York51-200398284
11PathaiMemphis, TN501-1,000283180
12Insilico MedicineBoston, MA201-50027929
13Vividion Therapeutics, INCSan Diego, CA201-500273222
14InsitroSouth San Francisco, CA201-500264166
15ChemaxonSan Diego, CA201-500200138
16Valo HealthNew York, NY51-200192146
17ABSCIVancouver, WA51-200187117
18Simulations Plus, INCDurham, NC201-500183115
19Formation BIOBoston, MA51-200180108
20Xaira TherapeuticsSouth San Francisco, CA51-200175124
21TreelineWatertown, MA51-200164133
22LarvolSan Francisco, CA51-20015756
23Genomenon, INCAnn Arbor, MI51-20013489
24Mstack AIHouston, TX51-20012955
25VoiantWaltham, MA201-50012680

Showing 25 of 850 drug discovery AI companies based in the United States

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Drug discovery AI companies based in the United States at a glance

As of Aug 28, 2026
1-10Median size (employees)
San FranciscoLargest hub · 72 HQs
9,262Contacts with mobile numbers
22Emails re-verified in last 30 days

Companies by employee count

1-10
468
11-50
287
51-200
69
201-500
13
501-1,000
6
1,001-5,000
6
10001+
1

Drug discovery AI companies by metro

MetroCompanies
Drug discovery AI companies in San Francisco72
Drug discovery AI companies in Cambridge55
Drug discovery AI companies in Boston53
Drug discovery AI companies in New York52
Drug discovery AI companies in San Diego43
Drug discovery AI companies in Palo Alto19
Drug discovery AI companies in South San Francisco19
Drug discovery AI companies in Chicago17

How this list was built

Source
The RevenueBase company graph: 21.3 million companies and 398.9 million professional contacts resolved from primary sources.
Inclusion
Companies whose own business descriptions match “drug discovery AI companies”, with match quality audited by blind human judging, and headquartered in the United States.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Contact records re-verify on a rolling cadence; 22 contacts on this list were re-verified in the last 30 days.
Refresh
Lists are refreshed periodically as the underlying company graph is re-verified. Last verified Aug 28, 2026.

Frequently asked

How many drug discovery AI companies are there based in the United States?

There are 850 drug discovery AI companies headquartered in the United States as of August 2026 (RevenueBase).

What is the largest company on this list?

Tempus AI, headquartered in Durham, tops this list with the largest team on record.

Which city has the most drug discovery AI companies?

San Francisco leads with 72 headquartered companies, followed by Cambridge (55) and Boston (53).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 12,385 verified decision-maker contacts tracked across these 850 companies.

How current is this list?

The list is refreshed periodically as the underlying company graph is re-verified. It was last verified on August 28, 2026.

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About this data

RevenueBase is a B2B contact data platform. Its company graph covers 21.3 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph, the same data that powers RevenueBase's B2B data products and the free research portal.