Company lists · Data refreshed September 2026

Top 25 Drug discovery AI companies based in the United States

Name: Drug discovery AI companies based in the United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 1, 2026 850 companies tracked

RevenueBase identified 850 drug discovery AI companies headquartered in the United States as of September 2026 and tracks 26,140 professional contacts across them, including 12,385 with verified work emails and 9,262 with mobile numbers. San Francisco is the largest hub.

This list covers drug discovery AI companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 1, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase Smart Search rating on every row Refreshed Sep 1, 2026 86% judged on-target in blind review

850Companies

26,140Contacts tracked

12,385Verified emails

9,262Mobile numbers

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The 25 largest drug discovery AI companies based in the United States

Ranked by team size

Top 25 of 850 drug discovery AI companies based in the United States, ranked by team size, largest first. Data refreshed Sep 1, 2026. RevenueBase Smart Search rates how each company's information relates to drug discovery AI companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#	Company	RevenueBase Smart Search	Headquarters	Employees	Contacts
1	Tempus AI	Indirect evidence	Durham, NC, United States	1,001-5,000	2,786 contacts →
	Indirect evidence “Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.” Source: RevenueBase Database · checked Sep 1, 2026
2	Arisglobal	Indirect evidence	Waltham, MA, United States	1,001-5,000	1,903 contacts →
	Indirect evidence “ArisGlobal is transforming the way today’s most successful life sciences companies develop breakthroughs and bring new products to market.” Source: RevenueBase Database · checked Sep 1, 2026
3	SAAMA	Indirect evidence	Glendale, AZ, United States	1,001-5,000	1,666 contacts →
	Indirect evidence “Saama develops life science solutions that accelerate the delivery of therapies to patients.” Source: RevenueBase Database · checked Sep 1, 2026
4	Caris Life Sciences	Indirect evidence	Irving, TX, United States	1,001-5,000	1,551 contacts →
	Indirect evidence “Caris Life Sciences® (Caris) is the leading next-generation TechBio company and precision medicine pioneer that is actively developing and delivering innovative solutions to…” Source: RevenueBase Database · checked Sep 1, 2026
5	Certara	Strong evidence	Blue Bell, PA, United States	1,001-5,000	1,244 contacts →
	Strong evidence “Certara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development.” Source: RevenueBase Database · checked Sep 1, 2026
6	Benchling	Partial evidence	Boston, MA, United States	501-1,000	841 contacts →
	Partial evidence “We are rebuilding biotech for the AI era.” Source: RevenueBase Database · checked Sep 1, 2026
7	Recursion	Indirect evidence	Salt Lake City, UT, United States	501-1,000	779 contacts →
	Indirect evidence “Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives.” Source: RevenueBase Database · checked Sep 1, 2026
8	Bostongene	Strong evidence	Waltham, MA, United States	501-1,000	434 contacts →
	Strong evidence “BostonGene is redefining cancer patient care and drug development through the integration of omnimodal data and AI.” Source: RevenueBase Database · checked Sep 1, 2026
9	Eikon Therapeutics	Indirect evidence	Millbrae, CA, United States	201-500	422 contacts →
	Indirect evidence “Eikon Therapeutics is a late-stage clinical biopharmaceutical company advancing a pipeline of potential therapies for patients with unmet medical needs.” Source: RevenueBase Database · checked Sep 1, 2026
10	qure.ai	Partial evidence	New York, United States	51-200	398 contacts →
	Partial evidence “Qure.ai is a health tech company that uses deep learning and Artificial Intelligence (AI) to make healthcare more accessible and equitable for patients worldwide.” Source: RevenueBase Database · checked Sep 1, 2026
11	Pathai	Partial evidence	Memphis, TN, United States	501-1,000	283 contacts →
	Partial evidence “PathAI's mission is to improve patient outcomes with AI-powered pathology.” Source: RevenueBase Database · checked Sep 1, 2026
12	Insilico Medicine	Partial evidence	Boston, MA, United States	201-500	279 contacts →
	Partial evidence “Insilico Medicine, a clinical stage biotech company powered by generative AI, is connecting biology, chemistry, and clinical trials analysis using next-generation AI systems.” Source: RevenueBase Database · checked Sep 1, 2026
13	Vividion Therapeutics, INC	Indirect evidence	San Diego, CA, United States	201-500	273 contacts →
	Indirect evidence Source: RevenueBase Database · checked Sep 1, 2026
14	Insitro	Partial evidence	South San Francisco, CA, United States	201-500	264 contacts →
	Partial evidence “insitro is the physical AI company unlocking causal human biology, founded and led by AI pioneer Daphne Koller.” Source: RevenueBase Database · checked Sep 1, 2026
15	Chemaxon	Indirect evidence	San Diego, CA, United States	201-500	200 contacts →
	Indirect evidence “Chemaxon is a leading cheminformatics company, setting the industry standard for quality and accuracy.” Source: RevenueBase Database · checked Sep 1, 2026
16	Valo Health	Strong evidence	New York, NY, United States	51-200	192 contacts →
	Strong evidence “Valo is a technology company built to transform drug discovery and development using large-scale data and AI-powered computation.” Source: RevenueBase Database · checked Sep 1, 2026
17	ABSCI	Strong evidence	Vancouver, WA, United States	51-200	187 contacts →
	Strong evidence “Absci is a data-first AI drug creation company designing differentiated therapeutics using generative AI.” Source: RevenueBase Database · checked Sep 1, 2026
18	Simulations Plus, INC	Strong evidence	Durham, NC, United States	201-500	183 contacts →
	Strong evidence “Simulations Plus is a leading provider of modeling and simulation software and consulting services supporting drug discovery, development research, and regulatory submissions.” Source: RevenueBase Database · checked Sep 1, 2026
19	Formation BIO	Strong evidence	Boston, MA, United States	51-200	180 contacts →
	Strong evidence “Formation Bio is an AI-native pharma company differentiated by radically more efficient drug development.” Source: RevenueBase Database · checked Sep 1, 2026
20	Xaira Therapeutics	Indirect evidence	South San Francisco, CA, United States	51-200	175 contacts →
	Indirect evidence “Xaira Therapeutics is an integrated biotechnology company driving advances in artificial intelligence to learn the language of life and transform how we treat disease.” Source: RevenueBase Database · checked Sep 1, 2026
21	Treeline	Indirect evidence	Watertown, MA, United States	51-200	164 contacts →
	Indirect evidence “Treeline (or Treeline Biosciences) is a privately held, clinical-stage biopharma company that aspires to make medicines at the highest level.” Source: RevenueBase Database · checked Sep 1, 2026
22	Larvol	Partial evidence	San Francisco, CA, United States	51-200	157 contacts →
	Partial evidence “AI-powered data and market intelligence solutions - We leverage AI to transform clinical trial data and market intelligence into actionable insights to accelerate pharma…” Source: RevenueBase Database · checked Sep 1, 2026
23	Genomenon, INC	Partial evidence	Ann Arbor, MI, United States	51-200	134 contacts →
	Partial evidence “The Real-world Evidence to validate a drug target, identify trial-eligible patients, or change a diagnosis already exists.” Source: RevenueBase Database · checked Sep 1, 2026
24	Mstack AI	Partial evidence	Houston, TX, United States	51-200	129 contacts →
	Partial evidence “Mstack is building an AI-native platform transforming chemical R&D and supply.” Source: RevenueBase Database · checked Sep 1, 2026
25	Voiant	Indirect evidence	Waltham, MA, United States	201-500	126 contacts →
	Indirect evidence “Three industry leading companies, MedQIA, WorldCare Clinical and DARC, have come together to form Voiant, the new leader in clinical trial imaging endpoint data.” Source: RevenueBase Database · checked Sep 1, 2026

RevenueBase Smart Search

RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: drug discovery AI companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.

Strong evidence: The company's own public description of its business names drug discovery AI companies.
Partial evidence: Its own public description names part of drug discovery AI companies, so it works in or next to the category without describing itself that way.
Indirect evidence: The description shown does not name drug discovery AI companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.

RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.

Showing 25 of 850 drug discovery AI companies based in the United States

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Drug discovery AI companies based in the United States at a glance

As of Sep 1, 2026

47.4%Verified-email coverage

35.4%Mobile-number coverage

30.8Average contacts per company

1-10Median size (employees)

8.5%Largest-city concentration · San Francisco

Sep 1, 2026Page data refreshed

Companies by employee count

1-10

468

11-50

287

51-200

201-500

501-1,000

1,001-5,000

10001+

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among drug discovery AI companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in the United States whose own description of what they do matches “drug discovery AI companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search: RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names drug discovery AI companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude: Companies whose own description does not clearly place them among drug discovery AI companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 12,385 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 1, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Drug discovery AI companies by metro

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names drug discovery AI companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many drug discovery AI companies are there based in the United States?

RevenueBase identified 850 drug discovery AI companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Tempus AI, headquartered in Durham, tops this list with the largest team on record.

Which city has the most drug discovery AI companies?

San Francisco leads with 72 headquartered companies, followed by Cambridge (55) and Boston (53).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 12,385 verified decision-maker contacts tracked across these 850 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 1, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.