Company lists · Data verified August 2026
Top 25 Drug discovery AI companies based in the United States
There are 850 drug discovery AI companies headquartered in the United States (RevenueBase, August 2026). RevenueBase tracks 26,140 professional contacts across them, including 12,385 with verified work emails and 9,262 with mobile numbers. San Francisco is the largest hub.
This list covers drug discovery AI companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Data current as of August 28, 2026.
The 25 largest drug discovery AI companies based in the United States
Ranked by team size| # | Company | Verified emails |
|---|---|---|
| 1 | Tempus AI | 1,709 |
| 2 | 476 | |
| 3 | SAAMA | 678 |
| 4 | 37 | |
| 5 | 876 | |
| 6 | 601 | |
| 7 | 515 | |
| 8 | 223 | |
| 9 | 309 | |
| 10 | 284 | |
| 11 | 180 | |
| 12 | 29 | |
| 13 | 222 | |
| 14 | 166 | |
| 15 | 138 | |
| 16 | Valo Health | 146 |
| 17 | 117 | |
| 18 | 115 | |
| 19 | 108 | |
| 20 | Xaira Therapeutics | 124 |
| 21 | Treeline | 133 |
| 22 | 56 | |
| 23 | 89 | |
| 24 | 55 | |
| 25 | Voiant | 80 |
Showing 25 of 850 drug discovery AI companies based in the United States
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Drug discovery AI companies based in the United States at a glance
As of Aug 28, 2026Companies by employee count
Drug discovery AI companies by metro
| Metro | Companies |
|---|---|
| Drug discovery AI companies in San Francisco | 72 |
| Drug discovery AI companies in Cambridge | 55 |
| Drug discovery AI companies in Boston | 53 |
| Drug discovery AI companies in New York | 52 |
| Drug discovery AI companies in San Diego | 43 |
| Drug discovery AI companies in Palo Alto | 19 |
| Drug discovery AI companies in South San Francisco | 19 |
| Drug discovery AI companies in Chicago | 17 |
How this list was built
- Source
- The RevenueBase company graph: 21.3 million companies and 398.9 million professional contacts resolved from primary sources.
- Inclusion
- Companies whose own business descriptions match “drug discovery AI companies”, with match quality audited by blind human judging, and headquartered in the United States.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Contact records re-verify on a rolling cadence; 22 contacts on this list were re-verified in the last 30 days.
- Refresh
- Lists are refreshed periodically as the underlying company graph is re-verified. Last verified Aug 28, 2026.
Frequently asked
How many drug discovery AI companies are there based in the United States?
There are 850 drug discovery AI companies headquartered in the United States as of August 2026 (RevenueBase).
What is the largest company on this list?
Tempus AI, headquartered in Durham, tops this list with the largest team on record.
Which city has the most drug discovery AI companies?
San Francisco leads with 72 headquartered companies, followed by Cambridge (55) and Boston (53).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 12,385 verified decision-maker contacts tracked across these 850 companies.
How current is this list?
The list is refreshed periodically as the underlying company graph is re-verified. It was last verified on August 28, 2026.
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About this data
RevenueBase is a B2B contact data platform. Its company graph covers 21.3 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph, the same data that powers RevenueBase's B2B data products and the free research portal.
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