Company lists · Data refreshed September 2026

Top 25 Digital therapy software companies based in the United States

RevenueBase identified 274 company matches for digital therapy software companies associated with the United States as of September 2026 and tracks 5,827 professional contacts across them, including 1,877 with verified work emails. New York is the largest hub.

This list covers company matches for digital therapy software companies associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed September 28, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Sep 28, 2026 How this list was built
274Companies
5,827Contacts tracked
1,877Verified emails
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The 25 largest digital therapy software companies based in the United States

Ranked by team size
Top 25 of 274 company matches for digital therapy software companies based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Sep 28, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchNew York, NY, United StatesHQ recorded Sep 28, 2026201-5001,064 contacts →

Exact match

“A leading provider of virtual mental health care, Talkspace provides convenient access to high-quality, evidence-based therapy, psychiatry, and self-guided support.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
2Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 2026501-1,000586 contacts →

Exact match

“We’re building a world where everyone has access to exceptional mental health care.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
3Exact matchMaynard, MA, United StatesHQ recorded Sep 28, 202651-200280 contacts →

Exact match

“Telemynd combines the power of personalized technology with the expertise of trained, supported professionals to deliver comprehensive mental health services that increase care…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
4Exact matchNew York, NY, United StatesHQ recorded Sep 28, 2026201-500212 contacts →

Exact match

“Resilience Lab is modernizing how clinicians work together to provide mental health care that’s high-quality, personalized, and accessible.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
5Exact matchNY, United StatesHQ recorded Sep 28, 202651-200158 contacts →

Exact match

“Click Therapeutics, Inc, develops, validates, and commercializes software as prescription medical treatments for people with unmet medical needs.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
6Exact matchRemote, United StatesHQ recorded Sep 28, 202651-200138 contacts →

Exact match

“Affect is a nationally-scaled, online provider of therapy and psychiatric services for mental health and substance use disorders.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
7Exact matchSan Mateo, CA, United StatesHQ recorded Sep 28, 202651-200131 contacts →

Exact match

“At Meru Health, our mission is deeply personal.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
8Exact matchBoston, MA, United StatesHQ recorded Sep 28, 202651-200126 contacts →

Exact match

“Linus Health is a Boston-based digital health company focused on transforming brain health for people across the world.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
9Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-50124 contacts →

Exact match

“Little Otter is a digital mental health company that offers holistic, evidence-backed care for children 0-18 and their families.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
10Exact matchNew York, NY, United StatesHQ recorded Sep 28, 202651-200119 contacts →

Exact match

“Mantra Health is a digital mental health clinic on a mission to improve young peoples' mental healthcare access through clinical services, software, and design.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
11Exact matchNew York, NY, United StatesHQ recorded Sep 28, 202651-200105 contacts →

Exact match

“SohoMD is a telepsychiatry and teletherapy organization, using technology to efficiently deliver high-quality psychiatric care to patients.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
12Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-50105 contacts →

Exact match

“Aura is an all-in-one app for mental wellbeing & sleep.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
13Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202651-200102 contacts →

Exact match

“We make it easy to access effective mental health care anywhere, anytime.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
14Exact matchNew York, NY, United StatesHQ recorded Sep 28, 202651-20092 contacts →

Exact match

“Kaia is a leading digital MSK company and was acquired by Sword Health in January 2026.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
15Exact matchBoston, MA, United StatesHQ recorded Sep 28, 2026501-1,00067 contacts →

Exact match

“SilverCloud® by Amwell® (NYSE: AMWL) is a leading digital mental health platform, enabling providers, health plans and employers to deliver clinically validated digital…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
16Exact matchMontgomery, AL, United StatesHQ recorded Sep 28, 202611-5067 contacts →

Exact match

“HCS has been building healthcare software since 1984.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
17Exact matchSilicon Valley, CA, United StatesHQ recorded Sep 28, 202611-5057 contacts →

Exact match

“Joyous PBC is an AI powered digital platform that enables patients to take charge of their mental health.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
18Exact matchBoca Raton, FL, United StatesHQ recorded Sep 28, 202651-20057 contacts →

Exact match

“ReachLink is redefining mental health care through innovation, accessibility, and impact.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
19Exact matchAtlanta, GA, United StatesHQ recorded Sep 28, 202651-20055 contacts →

Exact match

“We make it easier to access and deliver care, allowing mental health professionals to treat more people and individuals to focus on leading happier, more fulfilling lives.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
20Exact matchCarlsbad, CA, United StatesHQ recorded Sep 28, 202651-20046 contacts →

Exact match

“How we feel about ourselves, interact with others, and overcome obstacles in life makes an enormous difference in our ability to be happy and to succeed.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
21Exact matchSausalito, CA, United StatesHQ recorded Sep 28, 202611-5039 contacts →

Exact match

“Leading health plans, program providers, and over 100 communities across the U.S, rely on CredibleMind to empower member mental health anytime, anywhere.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
22Exact matchCody, WY, United StatesHQ recorded Sep 28, 202651-20037 contacts →

Exact match

“Calmerry is a trusted online therapy platform founded in 2020 as a response to the growing need for mental health support during lockdown.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
23Exact matchChicago, IL, United StatesHQ recorded Sep 28, 202611-5035 contacts →

Exact match

“Prevail Health is a leader in technology-based behavioral health and resilience building for a wide range of challenges from depression to PTSD to substance abuse.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
24Exact matchNew York, NY, United StatesHQ recorded Sep 28, 202611-5034 contacts →

Exact match

“GrayMatters Health (GMH) is a health technology company developing and marketing an interventional psychiatry suite powered by digital fMRI-Informed biomarkers.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
25Exact matchProvidence, RI, United StatesHQ recorded Sep 28, 202651-20034 contacts →

Exact match

“Revive Therapeutic Services is a licensed behavioral health agency serving Rhode Island and Massachusetts, built on the belief that quality psychiatric and therapeutic care should…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase

Showing 25 of 274 digital therapy software companies based in the United States

See the full list, filter by size, metro and specialty, and access 1,877 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Digital therapy software companies based in the United States at a glance

As of Sep 28, 2026
32.2%Verified-email coverage
21.3Average contacts per company
1-10Median size (employees)
12.8%Largest-city concentration · New York
Sep 28, 2026Page data refreshed

Companies by employee count

1-10
152
11-50
86
51-200
26
201-500
6
501-1,000
2
10001+
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 274 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “digital therapy software companies” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 1,877 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 28, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “digital therapy software companies”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many digital therapy software companies are there based in the United States?

RevenueBase identified 274 company matches for digital therapy software companies associated with the United States as of September 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Talkspace tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most digital therapy software companies?

New York leads with 35 company records, followed by San Francisco (33) and Boston (9).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 1,877 professional contacts with verified work emails tracked across these 274 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 28, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.