Company lists · Data refreshed September 2026

Top 25 Digestive enzyme manufacturers based in the United States

RevenueBase identified 69 company matches for digestive enzyme manufacturers associated with the United States as of September 2026 and tracks 915 professional contacts across them, including 374 with verified work emails. Chino is the largest hub.

This list covers company matches for digestive enzyme manufacturers associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed September 29, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Sep 29, 2026 How this list was built
69Companies
915Contacts tracked
374Verified emails
Explore this list → Free signup · no credit card · 500 free credits

The 25 largest digestive enzyme manufacturers based in the United States

Ranked by team size
Top 25 of 69 company matches for digestive enzyme manufacturers based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Sep 29, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchReno, NV, United StatesHQ recorded Sep 29, 202651-200118 contacts →

Exact match

“Optimizing Health & Performance Since 2004 BIOptimizers USA, Inc.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
2Exact matchVenice, FL, United StatesHQ recorded Sep 29, 2026201-500103 contacts →

Exact match

“Enzymedica produces cutting edge enzyme formulas that provide targeted support for digestive issues, food intolerances, cardiovascular issues, proper immune function and healthy…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
3Exact matchWaltham, MA, United StatesHQ recorded Sep 29, 202651-20083 contacts →

Exact match

“Alcresta Therapeutics is dedicated to developing and commercializing novel, enzyme-based products designed to address challenges faced by people living with gastrointestinal…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
4Exact matchWheat Ridge, CO, United StatesHQ recorded Sep 29, 202611-5066 contacts →

Exact match

“Physician's Choice manufacturers professional-grade supplements and nutritional products.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
5Exact matchPalm Harbor, FL, United StatesHQ recorded Sep 29, 202651-20039 contacts →

Exact match

“Our belief has always been that optimum health can best be achieved through proper nutrition, supplementation and an active lifestyle.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
6Exact matchChino, CA, United StatesHQ recorded Sep 29, 202611-5035 contacts →

Exact match

“Specialty Enzymes & Probiotics is your global resource for quality enzymes and probiotics.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
7Exact matchForsyth, MO, United StatesHQ recorded Sep 29, 202651-20030 contacts →

Exact match

“National Enzyme Company was acquired by Deerland Probiotics & Enzymes in July of 2018.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
8Exact matchChino, CA, United StatesHQ recorded Sep 29, 202611-5029 contacts →

Exact match

“Nowadays nearly everyone in the supplement industry is talking about gut health.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
9Exact matchLake Oswego, OR, United StatesHQ recorded Sep 29, 202611-5028 contacts →

Exact match

“Kirkman® is the leading manufacturer of nutritional supplements for individuals with special dietary requirements and sensitivities.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
10Exact matchLos Angeles, United StatesHQ recorded Sep 29, 20261-1021 contacts →

Exact match

“The brand that people trust not to upset their stomachs.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
11Exact matchIn, United StatesHQ recorded Sep 29, 202611-5014 contacts →

Exact match

“VitaCyte manufactures and supplies GMP Grade purified-defined Clostridium histolyticum collagenase and protease enzymes to researchers, commercial cell suppliers, and institutions…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
12Exact matchAnn Arbor, MI, United StatesHQ recorded Sep 29, 202611-5014 contacts →

Exact match

“With a multi-channel approach in unique market positions, OmneDiem® is advancing integrative wellness strategies by providing consumers, healthcare practitioners, distributors and…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
13Exact matchAustin, TX, United StatesHQ recorded Sep 29, 202611-5014 contacts →

Exact match

“Wonderbelly™ is a clean digestive medicine company that develops OTC products using the same active ingredient as the leading brands while removing artificial additives.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
14Exact matchScottsdale, AZ, United StatesHQ recorded Sep 29, 20261-1013 contacts →

Exact match

“Arthur Andrew Medical was founded on a very simple principle: Provide products that actually work.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
15Exact matchOrlando, FL, United StatesHQ recorded Sep 29, 202611-5013 contacts →

Exact match

“At Zenwise, we believe the key to good health is gut health.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
16Exact matchScottsdale, AZ, United StatesHQ recorded Sep 29, 202611-508 contacts →

Exact match

“Our philosophy is simple: we focus on identifying problems at their source.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
17Exact matchChino, CA, United StatesHQ recorded Sep 29, 202611-508 contacts →

Exact match

“AST Enzymes is a leading enzyme manufacturer providing healthcare professionals and consumers with pharmaceutical-grade enzyme supplements for cardiovascular, anti-inflammatory…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
18Exact matchKansas City, MO, United StatesHQ recorded Sep 29, 202611-507 contacts →

Exact match

“Enzymes Incorporated is a nutritional supplement company with over 85 years of experience specializing in digestive and therapeutic enzyme therapy.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
19Exact matchGreen Bay, WI, United StatesHQ recorded Sep 29, 202651-2005 contacts →

Exact match

“EuroMedica brand of dietary supplements is a leader in therapeutic formulations.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
20Exact matchCheyenne, WY, United StatesHQ recorded Sep 29, 202611-503 contacts →

Exact match

“Clinical Grade Nutrition - Since BioMatrix has provided specialized dietary supplements to support the body’s functional systems – with an emphasis on balancing and repairing the…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
21Exact matchMurrieta, CA, United StatesHQ recorded Sep 29, 202651-2003 contacts →

Exact match

“Super Easy Nutrition is one of the fastest growing and top selling plant-based dietary and nutritional supplements formulating company in the world.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
22Exact matchCleveland, OH, United StatesHQ recorded Sep 29, 202611-503 contacts →

Exact match

“KaraMD® and Alternative Health Solutions were founded by Dr.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
23Exact matchPortland, OR, United StatesHQ recorded Sep 29, 20261-102 contacts →

Exact match

“Enriching Gifts offers a revolutionary herbal diet supplement with digestive plant enzymes designed to assist you in restoring your immune system to a fully operational status.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
24Exact matchMadison, WI, United StatesHQ recorded Sep 29, 20261-101 contacts →

Exact match

“Loomis Enzymes® continues to help healthcare practitioners improve their patients' quality of life by providing the highest quality enzyme and herbal supplements available.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
25Exact matchLas Vegas, NV, United StatesHQ recorded Sep 29, 20261-101 contacts →

Exact match

“Started in 2015 to strive and create some of the best supplements known.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase

Showing 25 of 69 digestive enzyme manufacturers based in the United States

See the full list, filter by size, metro and specialty, and access 374 tracked professional contacts with verified work emails. Direct dials are available where recorded.

Free signup · no credit card

View the full list →

Digestive enzyme manufacturers based in the United States at a glance

As of Sep 29, 2026
40.9%Verified-email coverage
13.3Average contacts per company
1-10Median size (employees)
4.3%Largest-city concentration · Chino
Sep 29, 2026Page data refreshed

Companies by employee count

1-10
34
11-50
23
51-200
9
201-500
1
5,001-10,000
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 69 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “digestive enzyme manufacturers” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 374 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 29, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “digestive enzyme manufacturers”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many digestive enzyme manufacturers are there based in the United States?

RevenueBase identified 69 company matches for digestive enzyme manufacturers associated with the United States as of September 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Bioptimizers tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most digestive enzyme manufacturers?

Chino leads with 3 company records, followed by Austin (2) and Boulder (2).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 374 professional contacts with verified work emails tracked across these 69 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 29, 2026.

Ready to reach these companies? Verified emails and direct dials for all 69 digestive enzyme manufacturers based in the United States. Start with a free account, no credit card.

Download this list →

Related lists

About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.