Company lists · Data refreshed September 2026

Top 25 Defi venture capital firms based in San Francisco, United States

RevenueBase identified 97 company matches for defi venture capital firms associated with San Francisco, United States as of September 2026 and tracks 1,967 professional contacts across them, including 477 with verified work emails. Across the United States, San Francisco is the largest hub for this category.

This list covers company matches for defi venture capital firms associated with San Francisco, United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed September 28, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Sep 28, 2026 How this list was built
97Companies
1,967Contacts tracked
477Verified emails
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The 25 largest defi venture capital firms based in San Francisco, United States

Ranked by team size
Top 25 of 97 company matches for defi venture capital firms based in San Francisco, United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Sep 28, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 2026n/a711 contacts →

Exact match

“Hustle Fund is a venture capital firm investing in hilariously-early pre-seed founders.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
2Exact matchSan Francisco, United StatesHQ recorded Sep 28, 202651-200130 contacts →

Exact match

“Paradigm is a frontier technology investment firm led by Matt Huang and Alana Palmedo that builds and invests across crypto, AI, robotics, and other new frontiers from the…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
3Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202651-200105 contacts →

Exact match

“Human Capital is a multi-stage venture capital firm.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
4Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5094 contacts →

Exact match

“Blockchain Capital was founded in 2013 with the mission of helping entrepreneurs build world-class companies and projects based on blockchain technology – providing founders with…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
5Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5081 contacts →

Exact match

“SemperVirens is a San Francisco based venture capital firm investing in AI-native companies transforming the largest and most complex service markets in the economy: healthcare…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
6Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5062 contacts →

Exact match

“Founded in Industry Ventures has pioneered flexible capital solutions over the past 25+ years across the life cycle of venture – from seed- and early-stage investing to late-stage…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
7Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5047 contacts →

Exact match

“Crosslink, founded in 1989, is a premier early-stage venture capital firm with over $4.2B in assets.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
8Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 2026n/a39 contacts →

Exact match

“We invest in idea-stage and pre-seed fintechs globally, anchoring on founder-market fit.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
9Exact matchSan Francisco, United StatesHQ recorded Sep 28, 202611-5036 contacts →

Exact match

“Framework Ventures is a leading VC firm with a track record of partnering with winning founders.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
10Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 2026n/a36 contacts →

Exact match

“Robust is an early-stage, industry-agnostic venture capital firm that invests globally.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
11Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5032 contacts →

Exact match

“We set the standard in seed stage venture capital, backing founders with grit, audacity, and a spark of rebellion.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
12Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5029 contacts →

Exact match

“Builders believes it takes more than great technology to fix an antiquated industry.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
13Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5028 contacts →

Exact match

“Transpose Platform is redefining early-stage investing by backing the next generation of venture structures, accelerators, and the breakout companies they nurture.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
14Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 20261,001-5,00024 contacts →

Exact match

“Orange Collective invests at the center of two explosive forces: AI and YC.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
15Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 20261-1020 contacts →

Exact match

“Shield Capital is a team of veteran investors, founders and national security leaders who are helping founders build frontier solutions in cybersecurity, artificial intelligence…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
16Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5020 contacts →

Exact match

“At LBank Labs, we thrive on the power of connections and believe in fostering strong relationships within the industry.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
17Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 20261-1019 contacts →

Exact match

“Mana Ventures is a San Francisco based VC firm that invests in early stage software and deep tech companies.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
18Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5015 contacts →

Exact match

“Alsop Louie Partners is a team of seasoned investors who are entrepreneurs and executives with distinctive reputations.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
19Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 20261-1014 contacts →

Exact match

“Akkadian is a venture firm built on redefining strategic liquidity through inventive structures and trusted access.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
20Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 20261-1013 contacts →

Exact match

“Amity Ventures is a people-focused firm that supports founders of technology companies in building category-defining businesses.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
21Exact matchSan Francisco, United StatesHQ recorded Sep 28, 202611-5011 contacts →

Exact match

“Momentum 6 is a venture capital, venture builder, research, and marketing firm creating the leading blockchain companies of the future.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
22Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 20261-1010 contacts →

Exact match

“Advance Venture Partners (“AVP”) is an evergreen venture capital firm designed to make concentrated, long-duration investments in disruptive technology and technology-enabled…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
23Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 20261-1010 contacts →

Exact match

“We invest in near frontier tech that will change the world.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
24Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 20261-1010 contacts →

Exact match

“gCC is a boutique early-stage venture capital firm based in Silicon Valley.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
25Exact matchSan Francisco, United StatesHQ recorded Sep 28, 202611-509 contacts →

Exact match

“At R136, our mission is to propel creative entrepreneurs to a faster growth trajectory.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase

Showing 25 of 97 defi venture capital firms based in San Francisco, United States

See the full list, filter by size, metro and specialty, and access 477 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Defi venture capital firms based in San Francisco, United States at a glance

As of Sep 28, 2026
24.3%Verified-email coverage
20.3Average contacts per company
1-10Median size (employees)
Sep 28, 2026Page data refreshed

Companies by employee count

1-10
66
11-50
28
51-200
2
1,001-5,000
1

Email recency for this list is measured across the whole United States list rather than for San Francisco, so it is reported there. Company counts and contact totals on this page are exact for San Francisco, over 97 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with San Francisco, United States whose business descriptions match “defi venture capital firms” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 477 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 28, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Defi venture capital firms by metro in the United States

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “defi venture capital firms”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many defi venture capital firms are there based in San Francisco, United States?

RevenueBase identified 97 company matches for defi venture capital firms associated with San Francisco, United States as of September 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Hustle Fund tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city in the United States has the most defi venture capital firms?

San Francisco leads the United States with 97 company records, followed by New York (94) and Los Angeles (26).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 477 professional contacts with verified work emails tracked across these 97 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 28, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.