Company lists · Data refreshed September 2026

Top 25 Defi platforms based in the United States

RevenueBase identified 224 defi platforms headquartered in the United States as of September 2026 and tracks 1,955 professional contacts across them, including 290 with verified work emails and 450 with mobile numbers. New York is the largest hub.

This list covers defi platforms headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 1, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase Smart Search rating on every row Refreshed Sep 1, 2026 86% judged on-target in blind review
224Companies
1,955Contacts tracked
290Verified emails
450Mobile numbers
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The 25 largest defi platforms based in the United States

Ranked by team size
Top 25 of 224 defi platforms based in the United States, ranked by team size, largest first. Data refreshed Sep 1, 2026. RevenueBase Smart Search rates how each company's information relates to defi platforms: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceNew York, NY, United States51-200224 contacts →

Partial evidence

“Uniswap Labs builds products that help millions of people access DeFi simply and securely - from the Uniswap Web App and Wallet to crypto infrastructure like the Uniswap Trading…”

Source: RevenueBase Database · checked Sep 1, 2026
2Indirect evidenceHoboken, NJ, United States501-1,000123 contacts →

Indirect evidence

“Celsius helps over a million customers worldwide to find the path towards financial independence through a compounding yield service and instant low-cost loans accessible via a…”

Source: RevenueBase Database · checked Sep 1, 2026
3Indirect evidenceLos Angeles, CA, United States51-20063 contacts →

Indirect evidence

“SoLo Funds is the premier AI-powered community banking solution providing unparalleled returns and access to capital for millions of Americans, fueled by its AI-enhanced…”

Source: RevenueBase Database · checked Sep 1, 2026
4Indirect evidenceSan Francisco, CA, United States11-5059 contacts →

Indirect evidence

“At Zerion, we are on a mission to empower more people around the world with efficient, transparent, and censorship-resistant financial services.”

Source: RevenueBase Database · checked Sep 1, 2026
5Indirect evidenceHoboken, NJ, United States51-20055 contacts →

Indirect evidence

“Currency.com is a global digital finance provider.”

Source: RevenueBase Database · checked Sep 1, 2026
6Indirect evidenceMiami, FL, United States11-5028 contacts →

Indirect evidence

“Our mission is to build secure, fast, and cheap financial applications, starting with an order book exchange with market efficiency and price discovery while being fully…”

Source: RevenueBase Database · checked Sep 1, 2026
7Partial evidenceNew York, United States51-20020 contacts →

Partial evidence

“BlockApps is the core team behind STRATO, a Layer 1 Ethereum-compatible blockchain built to bring real-world assets (RWAs) into DeFi.”

Source: RevenueBase Database · checked Sep 1, 2026
8Partial evidenceNew York, NY, United States11-5017 contacts →

Partial evidence

“Lumena Labs is building the next generation of DeFi products, starting with Avantis.”

Source: RevenueBase Database · checked Sep 1, 2026
9Indirect evidenceSouth San Francisco, CA, United States51-20016 contacts →

Indirect evidence

“Openware is a blockchain infrastructure development company.”

Source: RevenueBase Database · checked Sep 1, 2026
10Indirect evidenceNew York, NY, United States11-5013 contacts →

Indirect evidence

“Loopscale is building the next generation of credit markets on efficient, open networks.”

Source: RevenueBase Database · checked Sep 1, 2026
11Partial evidenceSan Mateo, CA, United States11-5013 contacts →

Partial evidence

“Cred is a decentralized global lending platform that facilitates open access to credit anywhere and anytime.”

Source: RevenueBase Database · checked Sep 1, 2026
12Indirect evidenceLewes, DE, United States11-5012 contacts →

Indirect evidence

“Instadapp is here to democratise the finance through blockchain technology!”

Source: RevenueBase Database · checked Sep 1, 2026
13Indirect evidenceNew York, United States11-5011 contacts →

Indirect evidence

“The Ocean is the premier 0x-based relayer and liquidity pool for trading ERC20 Ethereum-based tokens.”

Source: RevenueBase Database · checked Sep 1, 2026
14Partial evidenceNashville, TN, United States11-5010 contacts →

Partial evidence

“Number Group is a DeFi-focused venture studio with the mission of incubating and building successful Web3 products from concept to market.”

Source: RevenueBase Database · checked Sep 1, 2026
15Indirect evidenceWY, United States11-5010 contacts →

Indirect evidence

“Coinshift is the largest, most comprehensive onchain business ecosystem.”

Source: RevenueBase Database · checked Sep 1, 2026
16Indirect evidenceSan Francisco, CA, United States11-5010 contacts →

Indirect evidence

“The legacy financial system is slow, inefficient, and constrained by intermediaries.”

Source: RevenueBase Database · checked Sep 1, 2026
17Partial evidenceNew York, NY, United States11-508 contacts →

Partial evidence

“Emporus is a technology-first asset management firm operating in decentralized finance (DeFi).”

Source: RevenueBase Database · checked Sep 1, 2026
18Indirect evidenceGreenwich, CT, United States11-508 contacts →

Indirect evidence

“Spritz is on a mission to connect Web3 users with real-world financial utility!”

Source: RevenueBase Database · checked Sep 1, 2026
19Indirect evidenceSan Francisco, CA, United States11-506 contacts →

Indirect evidence

“Access to financial services is a basic human right.”

Source: RevenueBase Database · checked Sep 1, 2026
20Indirect evidenceAtlanta, GA, United States11-506 contacts →

Indirect evidence

“We at bZx are creating innovative, cutting edge financial software with a focus on radical decentralization.”

Source: RevenueBase Database · checked Sep 1, 2026
21Indirect evidenceSan Francisco, CA, United States51-2005 contacts →

Indirect evidence

“TrustToken envisions a world where financial freedom is as accessible as the internet.”

Source: RevenueBase Database · checked Sep 1, 2026
22Partial evidenceNew York, NY, United States11-505 contacts →

Partial evidence

“Incyt provides DeFi trading software and Bitcoin miner financing, pioneering a new wave of finance for a blockchain powered world.”

Source: RevenueBase Database · checked Sep 1, 2026
23Partial evidenceMiami, FL, United States11-502 contacts →

Partial evidence

“OpulenceX stands as a multifaceted DeFi Protocol, offering an extensive array of cutting-edge products and services that redefine the landscape of decentralized finance.”

Source: RevenueBase Database · checked Sep 1, 2026
24Indirect evidenceLenexa, KS, United States51-2001 contacts →

Indirect evidence

“Diamante Blockchain Holdings Inc.”

Source: RevenueBase Database · checked Sep 1, 2026
25Partial evidenceSan Francisco, CA, United States11-501 contacts →

Partial evidence

“Sharky aims to bridge the gap between on chain assets and DeFi protocols, by creating contracts for lenders and borrowers, increasing liquidity in the ecosystem.”

Source: RevenueBase Database · checked Sep 1, 2026

Showing 25 of 224 defi platforms based in the United States

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Defi platforms based in the United States at a glance

As of Sep 1, 2026
14.8%Verified-email coverage
23.0%Mobile-number coverage
8.7Average contacts per company
11-50Median size (employees)
18.8%Largest-city concentration · New York
Sep 1, 2026Page data refreshed

Companies by employee count

1-10
108
11-50
97
51-200
17
201-500
1
501-1,000
1

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among defi platforms, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “defi platforms”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names defi platforms), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among defi platforms, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 290 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 1, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names defi platforms, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many defi platforms are there based in the United States?

RevenueBase identified 224 defi platforms headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Uniswap, headquartered in New York, tops this list with the largest team on record.

Which city has the most defi platforms?

New York leads with 42 headquartered companies, followed by San Francisco (31) and Miami (8).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 290 verified decision-maker contacts tracked across these 224 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 1, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.