Company lists · Data refreshed September 2026

Top 25 Defi investment firms based in the United States

RevenueBase identified 332 company matches for defi investment firms associated with the United States as of September 2026 and tracks 2,304 professional contacts across them, including 866 with verified work emails. New York is the largest hub.

This list covers company matches for defi investment firms associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed September 28, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Sep 28, 2026 How this list was built
332Companies
2,304Contacts tracked
866Verified emails
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The 25 largest defi investment firms based in the United States

Ranked by team size
Top 25 of 332 company matches for defi investment firms based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Sep 28, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchStamford, CT, United StatesHQ recorded Sep 28, 202651-200130 contacts →

Exact match

“Grayscale enables investors to access the digital economy through a family of future-forward investment products.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
2Exact matchSan Francisco, NY, United StatesHQ recorded Sep 28, 202651-200127 contacts →

Exact match

“Based in San Francisco, Bitwise is one of the largest and fastest-growing crypto asset managers.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
3Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5094 contacts →

Exact match

“Blockchain Capital was founded in 2013 with the mission of helping entrepreneurs build world-class companies and projects based on blockchain technology – providing founders with…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
4Exact matchStamford, CT, United StatesHQ recorded Sep 28, 202651-20081 contacts →

Exact match

“DCG is building a decentralized future to unlock economic and societal opportunity.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
5Exact matchMenlo Park, MA, United StatesHQ recorded Sep 28, 202611-5063 contacts →

Exact match

“Tribe Capital is a venture capital firm focused on capturing a perpetual edge in venture and crypto using data science.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
6Exact matchLos Angeles | New York, United StatesHQ recorded Sep 28, 202611-5061 contacts →

Exact match

“Arca is an asset management firm that creates and manages institutional grade products using crypto and blockchain technology.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
7Exact matchMenlo Park, CA, United StatesHQ recorded Sep 28, 202611-5051 contacts →

Exact match

“Network VC is the Venture Fund and Platform for a Decentralized Ecosystem of Independent VC Professionals”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
8Exact matchChapel Hill, NC, United StatesHQ recorded Sep 28, 202611-5047 contacts →

Exact match

“TrueBridge Capital Partners is an alternative asset management firm focused on generating superior returns in the venture capital industry.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
9Exact matchAustin, TX, United StatesHQ recorded Sep 28, 202611-5047 contacts →

Exact match

“Multicoin Capital is a thesis-driven investment firm.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
10Exact matchPalo Alto, CA, United StatesHQ recorded Sep 28, 202611-5045 contacts →

Exact match

“We are an engineering-led early-stage venture firm investing in companies and protocols uniquely enabled by cryptography and distributed systems.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
11Exact matchLos Angeles, CA, United StatesHQ recorded Sep 28, 202611-5044 contacts →

Exact match

“Wave Digital Assets (known as “Wave”), is a SEC-registered investment advisory firm that provides a unique combination of venture capital, fund, and private wealth management to…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
12Exact matchBrooklyn, United StatesHQ recorded Sep 28, 202611-5041 contacts →

Exact match

“Disruptive technology requires disruptive investors.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
13Exact matchSan Francisco, United StatesHQ recorded Sep 28, 202611-5036 contacts →

Exact match

“Framework Ventures is a leading VC firm with a track record of partnering with winning founders.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
14Exact matchNew York, NY, United StatesHQ recorded Sep 28, 202611-5032 contacts →

Exact match

“Liberty City Ventures is a venture capital fund and incubator with over $2.5 billion of assets under management.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
15Exact matchNew York, NY, United StatesHQ recorded Sep 28, 202651-20032 contacts →

Exact match

“Hi2 Global is an Investment as a Service global asset allocation platform that provides fin-tech enabled asset management, investment advisory, investment banking and family…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
16Exact matchNew York, NY, United StatesHQ recorded Sep 28, 202611-5031 contacts →

Exact match

“Variant is an early-stage crypto venture capital firm investing in an internet that turns users into owners.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
17Exact matchChicago, IL, United StatesHQ recorded Sep 28, 202651-20030 contacts →

Exact match

“Founded in 2017, CMT Digital is a leading global blockchain and web3 proprietary trading and venture capital firm focused on early-stage investments that accelerate the adoption…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
18Exact matchMiami, FL, United StatesHQ recorded Sep 28, 202611-5029 contacts →

Exact match

“We are a leading Web3-native investment manager with focus on fostering dynamic blockchain ecosystems & dedicated to help founders achieve their full potential.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
19Exact matchEvanston, IL, United StatesHQ recorded Sep 28, 202611-5025 contacts →

Exact match

“Evanston Capital Management, LLC (“Evanston Capital”) is an active investor in hedge funds, private equity, venture capital and blockchain and other strategies such as thematic…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
20Exact matchNew York, NY, United StatesHQ recorded Sep 28, 202611-5022 contacts →

Exact match

“Magna is building a platform to turn DeFi investments into financial primitives.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
21Exact matchMiami, FL, United StatesHQ recorded Sep 28, 202611-5022 contacts →

Exact match

“Big Brain Holdings is a global multi-stage investment firm backing founders accelerating emerging frontiers in technology.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
22Exact matchNew York, NY, United StatesHQ recorded Sep 28, 20261-1021 contacts →

Exact match

“RenGen is an investment and financial services firm focusing on investing in early stage, innovative blockchain technology companies.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
23Exact matchNew York, NY, United StatesHQ recorded Sep 28, 202611-5020 contacts →

Exact match

“10X aligns Wall Street with Silicon Valley and the world, bringing institutional capital to high growth technology ventures which are disrupting trillion dollar markets, as both…”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
24Exact matchSan Francisco, CA, United StatesHQ recorded Sep 28, 202611-5020 contacts →

Exact match

“At LBank Labs, we thrive on the power of connections and believe in fostering strong relationships within the industry.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase
25Exact matchLancaster, PA, United StatesHQ recorded Sep 28, 202611-5020 contacts →

Exact match

“Founded in 2019, Bursera Capital is among the world's oldest and top-performing digital asset hedge funds.”

Recorded in the RevenueBase company graph · Sep 28, 2026 · View company records in RevenueBase

Showing 25 of 332 defi investment firms based in the United States

See the full list, filter by size, metro and specialty, and access 866 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Defi investment firms based in the United States at a glance

As of Sep 28, 2026
37.6%Verified-email coverage
6.9Average contacts per company
1-10Median size (employees)
22.0%Largest-city concentration · New York
Sep 28, 2026Page data refreshed

Companies by employee count

1-10
240
11-50
81
51-200
9
201-500
1
10001+
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 332 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “defi investment firms” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 866 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 28, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “defi investment firms”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many defi investment firms are there based in the United States?

RevenueBase identified 332 company matches for defi investment firms associated with the United States as of September 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Grayscale Investments tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most defi investment firms?

New York leads with 73 company records, followed by San Francisco (28) and Miami (17).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 866 professional contacts with verified work emails tracked across these 332 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 28, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.