Company lists · Data refreshed November 2026

Top 25 Deep tech startups based in the United States

RevenueBase identified 222 company matches for deep tech startups associated with the United States as of November 2026 and tracks 2,462 professional contacts across them, including 819 with verified work emails. San Francisco is the largest hub.

This list covers company matches for deep tech startups associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed November 6, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Nov 6, 2026 How this list was built
222Companies
2,462Contacts tracked
819Verified emails
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The 25 largest deep tech startups based in the United States

Ranked by team size
Top 25 of 222 company matches for deep tech startups based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Nov 6, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchPrinceton, NJ, United StatesHQ recorded Nov 6, 202651-200123 contacts →

Exact match

“SOSV is the most active deep tech venture capital firm globally, investing at pre-seed (or at startup inception) supporting visionary founders intent on making a profound impact…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
2Exact matchCollege Station, TX, United StatesHQ recorded Nov 6, 202651-200122 contacts →

Exact match

“Lynntech, Inc, a rapidly growing technology development company specializing in transitioning innovative ideas and concepts into marketable technologies, is seeking highly…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
3Exact matchGolden, CO, United StatesHQ recorded Nov 6, 202651-200122 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
4Exact matchSouth Charleston, WV, United StatesHQ recorded Nov 6, 202651-200118 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
5Exact matchPalo Alto, CA, United StatesHQ recorded Nov 6, 202611-50102 contacts →

Exact match

“DCVC and its principals have backed brilliant people changing global-scale industries for over twenty years, helping create tens of billions of dollars of wealth for founders…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
6Exact matchWashington, DC, United StatesHQ recorded Nov 6, 202651-20092 contacts →

Exact match

“Named to the Inc Fastest-Growing Companies List at #1,294, FedTech is a venture firm that thrives at the intersection of US entrepreneurship, breakthrough technologies, and…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
7Exact matchSan Jose, MA, United StatesHQ recorded Nov 6, 202611-5063 contacts →

Exact match

“TDK Ventures is the global corporate venture capital arm of TDK Corporation.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
8Exact matchPalo Alto, CA, United StatesHQ recorded Nov 6, 202611-5058 contacts →

Exact match

“Playground Global is an early-stage deep tech venture capital firm investing in technical founders to transform ambitious ideas into high-impact businesses.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
9Exact matchNew York, NY, United StatesHQ recorded Nov 6, 202651-20054 contacts →

Exact match

“Mount Sinai Innovation Partners (MSIP), the technology commercialization arm of the Mount Sinai Health System, facilitates the transfer of discovery from the laboratory to the…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
10Exact matchSan Mateo, CA, United StatesHQ recorded Nov 6, 202611-5052 contacts →

Exact match

“Draper Associates is an early-stage venture capital firm, funding the future first.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
11Exact matchHopkinton, MA, United StatesHQ recorded Nov 6, 202611-5051 contacts →

Exact match

“Foresight Science & Technology specializes in commercialization, technology transfer, and intellectual property management.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
12Exact matchPittsburgh, PA, United StatesHQ recorded Nov 6, 202611-5034 contacts →

Exact match

“Rivers Agile is a deep tech consulting firm specializing in custom solutions for the healthcare, energy, robotics, and industrial sectors.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
13Exact matchLos Altos, CA, United StatesHQ recorded Nov 6, 202611-5033 contacts →

Exact match

“Founded in 2010, TSVC (formerly TEEC Angel Fund) is proud to be the first deeptech-focused venture capital firm founded by Tsinghua alumni in Silicon Valley.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
14Exact matchAshburn, VA, United StatesHQ recorded Nov 6, 202611-5025 contacts →

Exact match

“Novateur Research Solutions specializes in breakthrough innovation and solutions for government and commercial clients.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
15Exact matchRedwood City, CA, United StatesHQ recorded Nov 6, 202611-5023 contacts →

Exact match

“TLR Ventures creates foundational technology-based businesses to transform industries based on life and science.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
16Exact matchJackson, WY, United StatesHQ recorded Nov 6, 202611-5022 contacts →

Exact match

“Prime Movers invests in the founders of breakthrough scientific startups with the potential to transform billions of lives.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
17Exact matchAlbuquerque, NM, United StatesHQ recorded Nov 6, 202611-5022 contacts →

Exact match

“Roadrunner Venture Studios is a company creation factory.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
18Exact matchTucson, United StatesHQ recorded Nov 6, 202611-5019 contacts →

Exact match

“RCT employs investment professionals with expertise in the life sciences, development of medical devices and therapeutics, and financial management.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
19Exact matchSan Francisco, CA, United StatesHQ recorded Nov 6, 202611-5019 contacts →

Exact match

“rpv is a fully deployed DeepTech Venture fund focused on early stage, scientifically intensive ventures.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
20Exact matchSan Francisco, CA, United StatesHQ recorded Nov 6, 20261-1018 contacts →

Exact match

“Mana Ventures is a San Francisco based VC firm that invests in early stage software and deep tech companies.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
21Exact matchParole, MD, United StatesHQ recorded Nov 6, 20261-1018 contacts →

Exact match

“AI like ChatGPT can’t think or reason like a human.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
22Exact matchPalo Alto, CA, United StatesHQ recorded Nov 6, 20261-1017 contacts →

Exact match

“We are a Silicon Valley venture capital rm purpose-built to help startup teams win in frontier technology and services.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
23Exact matchSan Francisco, CA, United StatesHQ recorded Nov 6, 20261-1016 contacts →

Exact match

“At Bee Partners, we passionately believe today’s decades-long supercycle of AI-enabled machines will transform our world via software, hardware, and biology.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
24Exact matchSan Francisco, DE, United StatesHQ recorded Nov 6, 20261-1015 contacts →

Exact match

“We’re a Venture Studio co-building & funding AI-first B2B startups to scale profitably to $10M ARR faster.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
25Exact matchBoston, MA, United StatesHQ recorded Nov 6, 20261-1014 contacts →

Exact match

“Material Impact is a champion of the bravest ideas for the future, building companies from the ground up that turn material science and deep tech innovation into products that…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase

Showing 25 of 222 deep tech startups based in the United States

See the full list, filter by size, metro and specialty, and access 819 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Deep tech startups based in the United States at a glance

As of Nov 6, 2026
33.3%Verified-email coverage
11.1Average contacts per company
1-10Median size (employees)
14.4%Largest-city concentration · San Francisco
Nov 6, 2026Page data refreshed

Companies by employee count

1-10
156
11-50
50
51-200
13
501-1,000
1
1,001-5,000
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 222 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “deep tech startups” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 819 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on November 6, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Deep tech startups by metro

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “deep tech startups”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many deep tech startups are there based in the United States?

RevenueBase identified 222 company matches for deep tech startups associated with the United States as of November 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

SOSV tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most deep tech startups?

San Francisco leads with 32 company records, followed by New York (16) and Austin (8).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 819 professional contacts with verified work emails tracked across these 222 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on November 6, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.