Company lists · Data refreshed September 2026

Top 25 Decentralized application companies based in the United States

RevenueBase identified 257 decentralized application companies headquartered in the United States as of September 2026 and tracks 2,236 professional contacts across them, including 473 with verified work emails and 413 with mobile numbers. New York is the largest hub.

This list covers decentralized application companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 7, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 7, 2026 86% judged on-target in blind review
257Companies
2,236Contacts tracked
473Verified emails
413Mobile numbers
Explore this list → Free signup · no credit card · 500 free credits

The 25 largest decentralized application companies based in the United States

Ranked by team size
Top 25 of 257 decentralized application companies based in the United States, ranked by team size, largest first. Data refreshed Sep 7, 2026. RevenueBase Smart Search rates how each company's information relates to decentralized application companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceNew York, NY, United StatesHQ checked Sep 7, 202651-200228 contacts →

“Uniswap Labs builds products that help millions of people access DeFi simply and securely - from the Uniswap Web App and Wallet to crypto infrastructure like the Uniswap Trading…”

Source: company website · checked Sep 7, 2026
2Partial evidenceBerkeley, CA, United StatesHQ checked Sep 7, 202651-200178 contacts →

“Supercharging Web3 for a better, decentralized future Web3 needs faster, more secure, more decentralized blockchain infrastructure.”

Source: company website · checked Sep 7, 2026
3Indirect evidenceNew York, NY, United StatesHQ checked Sep 7, 202651-200123 contacts →

“Algorand is the blockchain that scales with your ambition.”

Source: company website · checked Sep 7, 2026
4Indirect evidenceSeattle, WA, United StatesHQ checked Sep 7, 202651-200108 contacts →

“Eigen Labs is an AI research lab building tools for human and agent coordination that preserve and maximize individual agency in the PostAGI era.”

Source: company website · checked Sep 7, 2026
5Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 7, 202651-200103 contacts →

“Tenderly creates a complete digital twin of any blockchain network so institutions, dev teams, asset managers, and risk managers can model every onchain move against a live system…”

Source: company website · checked Sep 7, 2026
6Indirect evidenceRemote First, United StatesHQ checked Sep 7, 202651-20089 contacts →

“OP Labs is the team building the technology that powers Optimism, the leading blockchain infrastructure provider enabling developers and enterprises to build the next generation…”

Source: company website · checked Sep 7, 2026
7Indirect evidenceMiami, FL, United StatesHQ checked Sep 7, 202651-20055 contacts →

“At Tatum, we believe blockchain is the future, and developing apps on the blockchain should be accessible.”

Source: company website · checked Sep 7, 2026
8Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 7, 202611-5053 contacts →

“At Zerion, we are on a mission to empower more people around the world with efficient, transparent, and censorship-resistant financial services.”

Source: company website · checked Sep 7, 2026
9Partial evidenceAustin, TX, United StatesHQ checked Sep 7, 202611-5046 contacts →

“Our suite of high-availability APIs and Developer Tools provide a Decentralization-as-a-Service platform to enable businesses and developers to leverage the full potential of…”

Source: company website · checked Sep 7, 2026
10Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 7, 202611-5040 contacts →

“Onboard users with wallets, build & deploy smart contracts, accept fiat with payments, and scale apps with infrastructure, on any EVM chain.”

Source: company website · checked Sep 7, 2026
11Partial evidenceNew York, NY, United StatesHQ checked Sep 7, 202651-20032 contacts →

“BlockTechBrew is an emerging blockchain development company with profound knowledge and experience in building and managing decentralized solutions.”

Source: company website · checked Sep 7, 2026
12Partial evidenceChicago, IL, United StatesHQ checked Sep 7, 202611-5029 contacts →

“Founded in 2016, Bloq builds the infrastructure, applications, and innovations that power Web3, as expressions of its Tokenization of Things™ methodology.”

Source: company website · checked Sep 7, 2026
13Indirect evidencePembroke Pines, FL, United StatesHQ checked Sep 7, 2026201-50029 contacts →

“InvoBlox is a global leader in blockchain product design and development founded by industry experts.”

Source: company website · checked Sep 7, 2026
14Indirect evidenceNew York, United StatesHQ checked Sep 7, 202651-20027 contacts →

“Infuy | Leading Innovation in Technology Blockchain Experts: Smart contracts, dApps, NFT marketplaces.”

Source: company website · checked Sep 7, 2026
15Indirect evidenceBellevue, WA, United StatesHQ checked Sep 7, 202611-5024 contacts →

“ArcBlock is transforming the way blockchain-enabled dApps and services are developed, managed and deployed by reimagining how these services are going to be created in the years…”

Source: company website · checked Sep 7, 2026
16Indirect evidenceNew York, NY, United StatesHQ checked Sep 7, 202611-5022 contacts →

“Magna is building a platform to turn DeFi investments into financial primitives.”

Source: company website · checked Sep 7, 2026
17Indirect evidenceFort Lauderdale, FL, United StatesHQ checked Sep 7, 202611-5021 contacts →

“Quantinium is a groundbreaking institutional-grade blockchain infrastructure that establishes a new industry standard for speed, security, and reliability.”

Source: company website · checked Sep 7, 2026
18Indirect evidenceBrooklyn, United StatesHQ checked Sep 7, 202651-20021 contacts →

“BlockApps is the core team behind STRATO, a Layer 1 Ethereum-compatible blockchain built to bring real-world assets (RWAs) into DeFi.”

Source: company website · checked Sep 7, 2026
19Indirect evidenceLas Vegas, NV, United StatesHQ checked Sep 7, 202611-5021 contacts →

“ADORIASOFT IS A TEAM OF ENGINEERS WITH A PRIMARY FOCUS ON BLOCKCHAIN AND DISTRIBUTED LEDGER TECHNOLOGIES.”

Source: company website · checked Sep 7, 2026
20Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 7, 202611-5018 contacts →

“Ambisafe is a globally recognized blockchain-based software provider.”

Source: company website · checked Sep 7, 2026
21Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 7, 202651-20016 contacts →

“Openware is a blockchain infrastructure development company.”

Source: company website · checked Sep 7, 2026
22Indirect evidenceMiddleton, DE, United StatesHQ checked Sep 7, 202611-5015 contacts →

“Rome Blockchain Labs is bringing humanity to the digital world of blockchain.”

Source: company website · checked Sep 7, 2026
23Partial evidenceDelaware, DE, United StatesHQ checked Sep 7, 202611-5011 contacts →

“We create and maintain a complex infrastructure layer where you can build your Blockchain & Crypto applications faster and at the same time - save from large monthly bills.”

Source: company website · checked Sep 7, 2026
24Indirect evidenceAustin, TN, United StatesHQ checked Sep 7, 202611-5010 contacts →

“Advantage Blockchain is a blockchain education and on-chain asset management firm.”

Source: company website · checked Sep 7, 2026
25Partial evidenceDraper, UT, United StatesHQ checked Sep 7, 202611-509 contacts →

“Kingdom Studios is a Web3 Blockchain Development Organization that is building the MythicSwap Decentralized Exchange (DEX) and DeFi Kingdoms, a Play-To-Earn (p2e) game that is…”

Source: company website · checked Sep 7, 2026

Showing 25 of 257 decentralized application companies based in the United States

See the full list, filter by size, metro and specialty, and get verified emails and direct dials for all 473 reachable decision-makers.

Free signup · no credit card

View the full list →

Decentralized application companies based in the United States at a glance

As of Sep 7, 2026
21.2%Verified-email coverage
18.5%Mobile-number coverage
8.7Average contacts per company
11-50Median size (employees)
9.3%Largest-city concentration · New York
Sep 7, 2026Page data refreshed

Companies by employee count

1-10
120
11-50
102
51-200
29
201-500
5
1,001-5,000
1

Freshness & accuracy

How recently the business emails on this list were verified

Email last verified

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among decentralized application companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “decentralized application companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names decentralized application companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among decentralized application companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 473 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 7, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names decentralized application companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many decentralized application companies are there based in the United States?

RevenueBase identified 257 decentralized application companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Uniswap, headquartered in New York, tops this list with the largest team on record.

Which city has the most decentralized application companies?

New York leads with 24 headquartered companies, followed by San Francisco (20) and Miami (8).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 473 verified decision-maker contacts tracked across these 257 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 7, 2026.

Ready to reach these companies? Verified emails and direct dials for all 257 decentralized application companies based in the United States. Start with a free account, no credit card.

Download this list →

Related lists

About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.