Company lists · Data refreshed September 2026
Top 25 Data science investors based in the United States
RevenueBase identified 375 data science investors headquartered in the United States as of September 2026 and tracks 3,748 professional contacts across them, including 1,418 with verified work emails. San Francisco is the largest hub.
This list covers data science investors headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 28, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest data science investors based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 193 contacts → | ||||
Indirect evidence “Khosla Ventures invests in companies that are bold, early and impactful.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 2 | 149 contacts → | ||||
Indirect evidence “Sapphire Ventures partners with Enterprise AI founders and the early-stage funds investing in them to build Companies of Consequence.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 3 | 125 contacts → | ||||
Indirect evidence “Samsung Next invests in bold and ambitious founders, focusing on transformative innovations in AI, intelligent machines, healthtech, consumer services, and frontier technology.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 4 | 119 contacts → | ||||
Indirect evidence “SOSV is the most active deep tech venture capital firm globally, investing at pre-seed (or at startup inception) supporting visionary founders intent on making a profound impact…” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 5 | 105 contacts → | ||||
Indirect evidence “DCVC and its principals have backed brilliant people changing global-scale industries for over twenty years, helping create tens of billions of dollars of wealth for founders…” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 6 | 87 contacts → | ||||
Indirect evidence “SignalFire is the first venture capital firm built like a technology company to better solve for the needs of founders.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 7 | 84 contacts → | ||||
Partial evidence “Seed, early stage and acceleration stage investor and partner for founders.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 8 | 77 contacts → | ||||
Indirect evidence “At Pennybacker, innovation is at the center of everything we do.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 9 | 75 contacts → | ||||
Indirect evidence “GLOBAL A.I.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 10 | 74 contacts → | ||||
Indirect evidence “25madison is a business-building and investment platform focused on modernizing legacy industries with technology.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 11 | 63 contacts → | ||||
Strong evidence “Tribe Capital is a venture capital firm focused on capturing a perpetual edge in venture and crypto using data science.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 12 | 60 contacts → | ||||
Partial evidence “At Optum Ventures, we look for exceptional teams with data-driven technologies and services that are poised to deeply disrupt the status quo.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 13 | 47 contacts → | ||||
Strong evidence “SYSTEM2 helps investors and operators integrate data science into their approach through sourcing, engineering, and analysis of big data as a service.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 14 | 45 contacts → | ||||
Indirect evidence “Glasswing Ventures is an early stage venture capital firm investing in the next generation of AI and frontier technology startups that are enabling the rise of the intelligent…” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 15 | 42 contacts → | ||||
Partial evidence “Cultivation Capital is a venture firm focused on investing in technology, life sciences, geospatial, and agtech companies whose ideas have the potential to transform the way we…” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 16 | 40 contacts → | ||||
Partial evidence “Foresite Labs creates companies at the intersection of AI/machine learning and science.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 17 | 38 contacts → | ||||
Indirect evidence “Unusual Ventures leads seed rounds in enterprise AI software startups.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 18 | 38 contacts → | ||||
Indirect evidence “MVP Ventures was founded in 2020 with the realization that a rethought model for venture investing could unlock significantly greater returns.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 19 | 37 contacts → | ||||
Indirect evidence “For over 15 years we have had the privilege of partnering with visionary entrepreneurs and teams as they build transformational companies.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 20 | 35 contacts → | ||||
Partial evidence “Mighty Capital is the VC firm that leverages the Product Alpha Effect, a data-backed way to produce outliers by reading product signals from a network.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 21 | 34 contacts → | ||||
Indirect evidence “Firm overview Mendoza Ventures is an early-stage and growth venture fund based in Boston.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 22 | 33 contacts → | ||||
Indirect evidence “Innovation Endeavors is an early-stage venture capital firm that invests in cutting-edge technologies to drive generational change in order to solve problems that matter.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 23 | 32 contacts → | ||||
Partial evidence “22C Capital is a private investment firm committed to delivering capital and critical resources to companies operating at the intersection of technology enablement and data…” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 24 | 31 contacts → | ||||
Indirect evidence “Founded in 2010, TSVC (formerly TEEC Angel Fund) is proud to be the first deeptech-focused venture capital firm founded by Tsinghua alumni in Silicon Valley.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 25 | 28 contacts → | ||||
Indirect evidence “VC + management firm accelerating AI, healthcare, fintech & deeptech startups with capital and strategic support.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: data science investors. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names data science investors.
- Partial evidence
- Its own public description names part of data science investors, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name data science investors. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 375 data science investors based in the United States
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Data science investors based in the United States at a glance
As of Sep 28, 2026Companies by employee count
Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 375 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among data science investors, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “data science investors”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names data science investors), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among data science investors, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 1,418 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 28, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Data science investors by metro
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names data science investors, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many data science investors are there based in the United States?
RevenueBase identified 375 data science investors headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Khosla Ventures, headquartered in Menlo Park, tops this list with the largest team on record.
Which city has the most data science investors?
San Francisco leads with 53 headquartered companies, followed by New York (48) and Boston (16).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,418 verified decision-maker contacts tracked across these 375 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 28, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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