Company lists · Data refreshed September 2026

Top 25 Custom enzyme manufacturers based in the United States

RevenueBase identified 82 custom enzyme manufacturers headquartered in the United States as of September 2026 and tracks 2,070 professional contacts across them, including 1,174 with verified work emails. San Diego is the largest hub.

This list covers custom enzyme manufacturers headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 29, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 29, 2026 86% judged on-target in blind review
82Companies
2,070Contacts tracked
1,174Verified emails
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The 25 largest custom enzyme manufacturers based in the United States

Ranked by team size
Top 25 of 82 custom enzyme manufacturers based in the United States, ranked by team size, largest first. Data refreshed Sep 29, 2026. RevenueBase Smart Search rates how each company's information relates to custom enzyme manufacturers: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceRedwood City, CA, United StatesHQ checked Sep 29, 202651-200270 contacts →

Indirect evidence

“Codexis is redefining what is possible in therapeutic development and manufacturing, leading the technology revolution with efficient, high-quality, and commercially proven…”

Source: RevenueBase Database · checked Sep 29, 2026
2Indirect evidenceNewark, CA, United StatesHQ checked Sep 29, 2026201-500140 contacts →

Indirect evidence

“Vector Laboratories serves and partners with scientists and industry teams developing the next generation of diagnostics, therapeutics, and biological insights.”

Source: RevenueBase Database · checked Sep 29, 2026
3Partial evidenceSeattle, WA, United StatesHQ checked Sep 29, 202651-20079 contacts →

Partial evidence

“Arzeda, The Protein Design Company™, is a synthetic biology company that creates novel proteins, enzymes and specialty chemical products that compete on performance, cost and…”

Source: RevenueBase Database · checked Sep 29, 2026
4Strong evidenceTroy, VA, United StatesHQ checked Sep 29, 202651-20054 contacts →

Strong evidence

“BIO-CAT provides the very latest enzyme technology and custom formulations.”

Source: RevenueBase Database · checked Sep 29, 2026
5Strong evidenceNorcross, GA, United StatesHQ checked Sep 29, 202651-20044 contacts →

Strong evidence

“EDT is a bio-industrial, value-added manufacturer of enzyme formulations employing biologically produced enzymes from renewable resources to solve traditional pulp & paper…”

Source: RevenueBase Database · checked Sep 29, 2026
6Partial evidenceLewisville, TX, United StatesHQ checked Sep 29, 202651-20043 contacts →

Partial evidence

“Bio-Synthesis is a biology contract manufacturer of high-quality nucleic acids, peptides and other molecular biology products for the research, diagnostic and therapeutic…”

Source: RevenueBase Database · checked Sep 29, 2026
7Indirect evidenceFrederick, MD, United StatesHQ checked Sep 29, 202611-5036 contacts →

Indirect evidence

“Kemp Proteins, LLC (formerly Kempbio) is a privately-owned, USA-based contract research and manufacturing organization located in Frederick, MD.”

Source: RevenueBase Database · checked Sep 29, 2026
8Indirect evidenceLakewood, NJ, United StatesHQ checked Sep 29, 202651-20036 contacts →

Indirect evidence

“Worthington is a privately owned, ISO9001 Certified.”

Source: RevenueBase Database · checked Sep 29, 2026
9Partial evidenceChino, CA, United StatesHQ checked Sep 29, 202611-5035 contacts →

Partial evidence

“Specialty Enzymes & Probiotics is your global resource for quality enzymes and probiotics.”

Source: RevenueBase Database · checked Sep 29, 2026
10Indirect evidenceJupiter, FL, United StatesHQ checked Sep 29, 202611-5029 contacts →

Indirect evidence

“Alphazyme was founded in 2018 by Christopher Benoit, Stephana Petrino and Chad Decker.”

Source: RevenueBase Database · checked Sep 29, 2026
11Partial evidenceNew York, United StatesHQ checked Sep 29, 202651-20024 contacts →

Partial evidence

“Creative Biolabs is specialized in providing custom biotechnology and pharmaceutical services that cover the full scope of biotechnology needs of early drug discovery and drug…”

Source: RevenueBase Database · checked Sep 29, 2026
12Partial evidenceAvon, NY, United StatesHQ checked Sep 29, 202651-20022 contacts →

Partial evidence

“Aldon is an ISO9001:2015 chemical manufacturer specializing in producing tailor-made chemical compounds and formulations based on specific client requirements.”

Source: RevenueBase Database · checked Sep 29, 2026
13Indirect evidenceMilwaukee, WI, United StatesHQ checked Sep 29, 202651-20017 contacts →

Indirect evidence

“Founded in 1985 in Milwaukee, Wisconsin, Molecular Biology Resources, Inc.(MBR) has earned the reputation as a world leader in biochemical manufacturing.”

Source: RevenueBase Database · checked Sep 29, 2026
14Partial evidenceBoston, United StatesHQ checked Sep 29, 202611-5014 contacts →

Partial evidence

“Exceptionally Affordable Enzymes At Fermatix, we’re on a mission to fuel scientific exploration by providing high-quality enzymes and other reagents at the lowest possible prices.”

Source: RevenueBase Database · checked Sep 29, 2026
15Strong evidenceIn, United StatesHQ checked Sep 29, 202611-5014 contacts →

Strong evidence

“VitaCyte manufactures and supplies GMP Grade purified-defined Clostridium histolyticum collagenase and protease enzymes to researchers, commercial cell suppliers, and institutions…”

Source: RevenueBase Database · checked Sep 29, 2026
16Partial evidenceNew York, NY, United StatesHQ checked Sep 29, 202611-5013 contacts →

Partial evidence

“Enzyme Development Corporation is a biotechnology company specializing in enzymes for food processing, animal feed, nutritional supplements, brewing, and distilling.”

Source: RevenueBase Database · checked Sep 29, 2026
17Partial evidenceDenver, CO, United StatesHQ checked Sep 29, 20261-1010 contacts →

Partial evidence

“Cascade Bio is creating more productive enzymes for economical biomanufacturing of sustainable chemicals.”

Source: RevenueBase Database · checked Sep 29, 2026
18Partial evidenceFarmingdale, NJ, United StatesHQ checked Sep 29, 20261-1010 contacts →

Partial evidence

“Sarchem Laboratories offers a combined 60 years of professional experience in the field of pharmaceutical intermediaries, specializing in custom synthesis.”

Source: RevenueBase Database · checked Sep 29, 2026
19Indirect evidencePasadena, CA, United StatesHQ checked Sep 29, 20261-109 contacts →

Indirect evidence

“Protabit LLC engineers proteins for industrial, agricultural, and healthcare applications.”

Source: RevenueBase Database · checked Sep 29, 2026
20Indirect evidenceSan Diego, CA, United StatesHQ checked Sep 29, 20261-108 contacts →

Indirect evidence

“Provider of development and contract manufacturing services across the life sciences and biotech industries.”

Source: RevenueBase Database · checked Sep 29, 2026
21Strong evidenceChino, CA, United StatesHQ checked Sep 29, 202611-508 contacts →

Strong evidence

“AST Enzymes is a leading enzyme manufacturer providing healthcare professionals and consumers with pharmaceutical-grade enzyme supplements for cardiovascular, anti-inflammatory…”

Source: RevenueBase Database · checked Sep 29, 2026
22Indirect evidenceSomerset, NJ, United StatesHQ checked Sep 29, 202611-507 contacts →

Indirect evidence

“LifeTein®, located in Somerset, New Jersey, was founded in 2008 with a simple vision: to increase both the quality and understanding of life one protein at a time.”

Source: RevenueBase Database · checked Sep 29, 2026
23Partial evidenceWatertown, MA, United StatesHQ checked Sep 29, 20261-106 contacts →

Partial evidence

“Pando is an AI-driven synthetic biology company revolutionizing enzyme engineering for the pharmaceutical manufacturing and life science tools.”

Source: RevenueBase Database · checked Sep 29, 2026
24Indirect evidenceTampa, FL, United StatesHQ checked Sep 29, 20261-106 contacts →

Indirect evidence

“In 2023 Biocatalysts Ltd.”

Source: RevenueBase Database · checked Sep 29, 2026
25Partial evidenceChino, CA, United StatesHQ checked Sep 29, 202611-506 contacts →

Partial evidence

“Specialty Enzymes & Biotechnologies is pleased to announce a new addition to our family of companies: Enzyme Innovation.”

Source: RevenueBase Database · checked Sep 29, 2026

Showing 25 of 82 custom enzyme manufacturers based in the United States

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Custom enzyme manufacturers based in the United States at a glance

As of Sep 29, 2026
56.7%Verified-email coverage
25.2Average contacts per company
11-50Median size (employees)
6.1%Largest-city concentration · San Diego
Sep 29, 2026Page data refreshed

Companies by employee count

1-10
38
11-50
26
51-200
13
201-500
3
501-1,000
1
1,001-5,000
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 82 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among custom enzyme manufacturers, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “custom enzyme manufacturers”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names custom enzyme manufacturers), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among custom enzyme manufacturers, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 1,174 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 29, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names custom enzyme manufacturers, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many custom enzyme manufacturers are there based in the United States?

RevenueBase identified 82 custom enzyme manufacturers headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Codexis, INC, headquartered in Redwood City, tops this list with the largest team on record.

Which city has the most custom enzyme manufacturers?

San Diego leads with 5 headquartered companies, followed by Chino (3) and New York (3).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,174 verified decision-maker contacts tracked across these 82 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 29, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.