Company lists · Data refreshed September 2026

Top 25 Computational biology companies based in the United States

RevenueBase identified 618 computational biology companies headquartered in the United States as of September 2026 and tracks 20,515 professional contacts across them, including 10,567 with verified work emails. San Diego is the largest hub.

This list covers computational biology companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 19, 2026 86% judged on-target in blind review
618Companies
20,515Contacts tracked
10,567Verified emails
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The 25 largest computational biology companies based in the United States

Ranked by team size
Top 25 of 618 computational biology companies based in the United States, ranked by team size, largest first. Data refreshed Sep 19, 2026. RevenueBase Smart Search rates how each company's information relates to computational biology companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceChicago, IL, United StatesHQ checked Sep 19, 20261,001-5,0002,758 contacts →

Indirect evidence

“Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.”

Source: RevenueBase Database · checked Sep 19, 2026
2Indirect evidenceIrving, TX, United StatesHQ checked Sep 19, 20261,001-5,0001,556 contacts →

Indirect evidence

“Caris Life Sciences® (Caris) is the leading next-generation TechBio company and precision medicine pioneer that is actively developing and delivering innovative solutions to…”

Source: RevenueBase Database · checked Sep 19, 2026
3Indirect evidenceRadnor, PA, United StatesHQ checked Sep 19, 20261,001-5,0001,237 contacts →

Indirect evidence

“Certara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development.”

Source: RevenueBase Database · checked Sep 19, 2026
4Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 19, 2026501-1,0001,230 contacts →

Partial evidence

“Twist Bioscience is a synthetic biology company based in South San Francisco, California.”

Source: RevenueBase Database · checked Sep 19, 2026
5Partial evidenceNew York, NY, United StatesHQ checked Sep 19, 2026501-1,000957 contacts →

Partial evidence

“Schrödinger’s industry-leading computational platform facilitates the research efforts of biopharmaceutical and industrial companies, academic institutions, and government…”

Source: RevenueBase Database · checked Sep 19, 2026
6Partial evidenceSalt Lake City, UT, United StatesHQ checked Sep 19, 2026501-1,000793 contacts →

Partial evidence

“Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives.”

Source: RevenueBase Database · checked Sep 19, 2026
7Partial evidenceBoston, MA, United StatesHQ checked Sep 19, 2026501-1,000787 contacts →

Partial evidence

“Ginkgo Bioworks builds the tools that make biology easier to engineer for everyone.”

Source: RevenueBase Database · checked Sep 19, 2026
8Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 19, 2026501-1,000550 contacts →

Partial evidence

“Standard BioTools delivers the leading proteomic and multi-omic solutions that enable researchers to discover unique biological insights not accessible by other technologies.”

Source: RevenueBase Database · checked Sep 19, 2026
9Indirect evidenceWaltham, MA, United StatesHQ checked Sep 19, 2026501-1,000383 contacts →

Indirect evidence

“BostonGene is redefining cancer patient care and drug development through the integration of omnimodal data and AI.”

Source: RevenueBase Database · checked Sep 19, 2026
10Indirect evidenceCharlestown, MA, United StatesHQ checked Sep 19, 2026501-1,000369 contacts →

Indirect evidence

“Velsera was formed in 2023 through the shared vision of Seven Bridges and Pierian, with a mission to accelerate the discovery, development, and delivery of life-changing insights.”

Source: RevenueBase Database · checked Sep 19, 2026
11Partial evidenceBoston, MA, United StatesHQ checked Sep 19, 2026201-500281 contacts →

Partial evidence

“Insilico Medicine, a clinical stage biotech company powered by generative AI, is connecting biology, chemistry, and clinical trials analysis using next-generation AI systems.”

Source: RevenueBase Database · checked Sep 19, 2026
12Indirect evidenceBoulder, CO, United StatesHQ checked Sep 19, 202651-200228 contacts →

Indirect evidence

“Watchmaker Genomics is a biotechnology company that specializes in advanced enzymology to develop precision tools for life sciences.”

Source: RevenueBase Database · checked Sep 19, 2026
13Indirect evidencePleasanton, CA, United StatesHQ checked Sep 19, 2026201-500219 contacts →

Indirect evidence

“Here's the deal.”

Source: RevenueBase Database · checked Sep 19, 2026
14Partial evidenceLexington, MA, United StatesHQ checked Sep 19, 202651-200191 contacts →

Partial evidence

“Valo is a technology company built to transform drug discovery and development using large-scale data and AI-powered computation.”

Source: RevenueBase Database · checked Sep 19, 2026
15Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 19, 202651-200179 contacts →

Indirect evidence

“Xaira Therapeutics is an integrated biotechnology company driving advances in artificial intelligence to learn the language of life and transform how we treat disease.”

Source: RevenueBase Database · checked Sep 19, 2026
16Indirect evidenceTinley Park, IL, United StatesHQ checked Sep 19, 2026201-500179 contacts →

Indirect evidence

“Hematogenix, a global cancer-focused life science company serving the pharmaceutical & biotechnology industry as well as community physicians.”

Source: RevenueBase Database · checked Sep 19, 2026
17Partial evidenceCambridge, MA, United StatesHQ checked Sep 19, 202651-200160 contacts →

Partial evidence

“Ultivue recently merged with Vizgen to lead the next frontier of innovation in spatial biology and multi-omics.”

Source: RevenueBase Database · checked Sep 19, 2026
18Indirect evidenceSan Carlos, WA, United StatesHQ checked Sep 19, 202651-200155 contacts →

Indirect evidence

“Born from the founders’ recognition that their diverse but complementary skills and experiences would enable them to successfully address challenges that others had not, Nautilus…”

Source: RevenueBase Database · checked Sep 19, 2026
19Indirect evidenceNew York, NY, United StatesHQ checked Sep 19, 202651-200149 contacts →

Indirect evidence

“D.”

Source: RevenueBase Database · checked Sep 19, 2026
20Indirect evidenceColorado Springs, CO, United StatesHQ checked Sep 19, 202651-200136 contacts →

Indirect evidence

“Aliri is committed to solving industry challenges by bringing innovative bioanalysis and spatial solutions to biotech and pharma, as the complexity of the drug development…”

Source: RevenueBase Database · checked Sep 19, 2026
21Indirect evidenceSan Diego, CA, United StatesHQ checked Sep 19, 202651-200135 contacts →

Indirect evidence

“Agena Bioscience® empowers research laboratories worldwide to deliver scalable targeted genomic data.”

Source: RevenueBase Database · checked Sep 19, 2026
22Partial evidenceNewark, CA, United StatesHQ checked Sep 19, 202651-200124 contacts →

Partial evidence

“Bio-Techne Spatial, a leader in applied spatial biology solutions, empowers scientists and clinicians around the world to push the boundaries of science and medicine.”

Source: RevenueBase Database · checked Sep 19, 2026
23Indirect evidenceNewark, CA, United StatesHQ checked Sep 19, 202651-200122 contacts →

Indirect evidence

“ATUM is an industry-leading provider of life science tools and solutions.”

Source: RevenueBase Database · checked Sep 19, 2026
24Partial evidenceSanta Fe, NM, United StatesHQ checked Sep 19, 202651-200121 contacts →

Partial evidence

“OpenEye, Cadence Molecular Sciences is an industry leader in computational molecular design based on decades of delivering rapid, robust, and scalable software, toolkits, and…”

Source: RevenueBase Database · checked Sep 19, 2026
25Indirect evidenceBoston, MA, United StatesHQ checked Sep 19, 202651-200105 contacts →

Indirect evidence

“Asimov builds tools to program living cells.”

Source: RevenueBase Database · checked Sep 19, 2026

Showing 25 of 618 computational biology companies based in the United States

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Computational biology companies based in the United States at a glance

As of Sep 19, 2026
51.5%Verified-email coverage
33.2Average contacts per company
1-10Median size (employees)
6.5%Largest-city concentration · San Diego
Sep 19, 2026Page data refreshed

Companies by employee count

1-10
328
11-50
188
51-200
69
201-500
17
501-1,000
10
1,001-5,000
5
10001+
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 618 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among computational biology companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “computational biology companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names computational biology companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among computational biology companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 10,567 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names computational biology companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many computational biology companies are there based in the United States?

RevenueBase identified 618 computational biology companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Tempus AI, headquartered in Chicago, tops this list with the largest team on record.

Which city has the most computational biology companies?

San Diego leads with 40 headquartered companies, followed by Boston (37) and San Francisco (31).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 10,567 verified decision-maker contacts tracked across these 618 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.