Company lists · Data refreshed September 2026

Top 25 Cognitive enhancement device companies based in the United States

RevenueBase identified 119 cognitive enhancement device companies headquartered in the United States as of September 2026 and tracks 1,050 professional contacts across them, including 272 with verified work emails. New York is the largest hub.

This list covers cognitive enhancement device companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 19, 2026 86% judged on-target in blind review
119Companies
1,050Contacts tracked
272Verified emails
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The 25 largest cognitive enhancement device companies based in the United States

Ranked by team size
Top 25 of 119 cognitive enhancement device companies based in the United States, ranked by team size, largest first. Data refreshed Sep 19, 2026. RevenueBase Smart Search rates how each company's information relates to cognitive enhancement device companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceBoston, MA, United StatesHQ checked Sep 19, 202651-200126 contacts →

Indirect evidence

“Linus Health is a Boston-based digital health company focused on transforming brain health for people across the world.”

Source: RevenueBase Database · checked Sep 19, 2026
2Indirect evidenceSomerville, MA, United StatesHQ checked Sep 19, 202651-20094 contacts →

Indirect evidence

“BrainCo’s leadership draws on deep experience in neuroscience research and expertise in education to deliver entirely new applications of brainwave technology in the education…”

Source: RevenueBase Database · checked Sep 19, 2026
3Indirect evidenceBoston, MA, United StatesHQ checked Sep 19, 202611-5084 contacts →

Indirect evidence

“Pison is advancing the frontier of human potential with the world’s first AI-infused, neural biosensing platform.”

Source: RevenueBase Database · checked Sep 19, 2026
4Indirect evidenceNew York, NY, United StatesHQ checked Sep 19, 202611-5060 contacts →

Indirect evidence

“Thesis targets key neurotransmitters and hormones tied to focus, learning, motivation, memory, stress resilience, and long-term brain health.”

Source: RevenueBase Database · checked Sep 19, 2026
5Indirect evidenceHolliston, MA, United StatesHQ checked Sep 19, 202611-5046 contacts →

Indirect evidence

“COMPANY OVERVIEW NeuroSync (neurosync.health) is a next gen neurotechnology company that delivers a digital health platform for practitioners who assess brain health and optimize…”

Source: RevenueBase Database · checked Sep 19, 2026
6Indirect evidenceCulver City, United StatesHQ checked Sep 19, 202611-5045 contacts →

Indirect evidence

“Kernel builds unmatched neurotechnology to make brain health measurable, actionable, and accessible, through world-class hardware, software, and science.”

Source: RevenueBase Database · checked Sep 19, 2026
7Indirect evidenceNew York, United StatesHQ checked Sep 19, 202611-5024 contacts →

Indirect evidence

“i-BrainTech makes the brain measurable and trainable.”

Source: RevenueBase Database · checked Sep 19, 2026
8Indirect evidenceMountain View, CA, United StatesHQ checked Sep 19, 202611-5021 contacts →

Indirect evidence

“At NextSense, we’re on a mission to restore energy, joy, and purpose in everyday life through the development of intuitive and accessible brain health technology.”

Source: RevenueBase Database · checked Sep 19, 2026
9Indirect evidenceNew York City, NY, United StatesHQ checked Sep 19, 20261-1018 contacts →

Indirect evidence

“Opal is The Focus Company™ Our mission is to empower humans to focus better every day.”

Source: RevenueBase Database · checked Sep 19, 2026
10Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 202611-5018 contacts →

Partial evidence

“Attune Neurosciences is a clinical-stage medical device company dedicated to improving human health and performance through clinically-proven, non-invasive neurostimulation…”

Source: RevenueBase Database · checked Sep 19, 2026
11Indirect evidenceNew York, NY, United StatesHQ checked Sep 19, 20261-1014 contacts →

Indirect evidence

“Vital Neuro is transforming how people and organizations approach mental performance, patient care, and human resilience.”

Source: RevenueBase Database · checked Sep 19, 2026
12Indirect evidenceLancaster, PA, United StatesHQ checked Sep 19, 202611-5013 contacts →

Indirect evidence

“Reflexion started after it’s cofounder crashed headfirst into the boards during an ice hockey game and was left with a severe concussion.”

Source: RevenueBase Database · checked Sep 19, 2026
13Indirect evidenceNewport Beach, CA, United StatesHQ checked Sep 19, 202611-5012 contacts →

Indirect evidence

“Neurologics pairs industry-leading technology and medical science to produce an accurate assessment of your brain that forms the basis for effective optimization.”

Source: RevenueBase Database · checked Sep 19, 2026
14Partial evidenceBrooklyn, United StatesHQ checked Sep 19, 20261-1011 contacts →

Partial evidence

“A Superdevice for Mental Health OAK, the apex brain stimulation wearable for neuropsychiatric and cognitive health, is the result of 15 years of clinical research and product…”

Source: RevenueBase Database · checked Sep 19, 2026
15Indirect evidenceSanta Monica, CA, United StatesHQ checked Sep 19, 202611-5011 contacts →

Indirect evidence

“TruBrain is a Venture Capital-backed functional food and beverage brand that delivers improved mental endurance and verbal fluency, validated by biomarker data.”

Source: RevenueBase Database · checked Sep 19, 2026
16Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 202611-5011 contacts →

Indirect evidence

“A company dedicated to food-based brain nutrition with real and delicious products to support brain development, performance and health.”

Source: RevenueBase Database · checked Sep 19, 2026
17Indirect evidenceSpotsylvania, VA, United StatesHQ checked Sep 19, 202611-509 contacts →

Indirect evidence

“Solutions for a Smarter World.”

Source: RevenueBase Database · checked Sep 19, 2026
18Indirect evidenceVancouver, WA, United StatesHQ checked Sep 19, 202651-2009 contacts →

Indirect evidence

“Nootopia is the absolute apex of brain-enhancing supplements where deeper focus, more creativity, social command, and more are made possible.”

Source: RevenueBase Database · checked Sep 19, 2026
19Indirect evidenceDurham, NC, United StatesHQ checked Sep 19, 20261-109 contacts →

Indirect evidence

“We're a small but rapidly growing neurotechnology company based in Durham, North Carolina.”

Source: RevenueBase Database · checked Sep 19, 2026
20Partial evidenceHartford, CT, United StatesHQ checked Sep 19, 20261-109 contacts →

Partial evidence

“Oscillo Biosciences, a pre-commercial neurotechnology company, has developed a non-invasive, clinically validated intervention for individuals with memory and cognitive…”

Source: RevenueBase Database · checked Sep 19, 2026
21Partial evidencePhiladelphia, PA, United StatesHQ checked Sep 19, 20261-108 contacts →

Partial evidence

“We are creating the first, clinical-grade, cognitive wearable for active situations powered by nanotechnology sensors, machine learning, and breakthrough research.”

Source: RevenueBase Database · checked Sep 19, 2026
22Partial evidenceTampa, FL, United StatesHQ checked Sep 19, 202611-506 contacts →

Partial evidence

“At NeuroEM, our mission is to revolutionize the treatment of cognitive decline through our groundbreaking Transcranial Electromagnetic Treatment leveraging Radio Frequencies…”

Source: RevenueBase Database · checked Sep 19, 2026
23Indirect evidenceAuburn, WA, United StatesHQ checked Sep 19, 20261-106 contacts →

Indirect evidence

“1 Nootropic Brand Amazon Best Seller”

Source: RevenueBase Database · checked Sep 19, 2026
24Strong evidenceProvidence, RI, United StatesHQ checked Sep 19, 20261-106 contacts →

Strong evidence

“ni2o is developing AI-driven brain-computer interfaces for the treatment of neurological disorders and cognitive enhancement.”

Source: RevenueBase Database · checked Sep 19, 2026
25Partial evidenceNaperville, IL, United StatesHQ checked Sep 19, 20261-106 contacts →

Partial evidence

“At Mastermind Cognitive Training, we enhance your skills using advanced neuroscience protocols, proven eye-strengthening techniques, and the latest in virtual reality and tablet…”

Source: RevenueBase Database · checked Sep 19, 2026

Showing 25 of 119 cognitive enhancement device companies based in the United States

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Cognitive enhancement device companies based in the United States at a glance

As of Sep 19, 2026
25.9%Verified-email coverage
8.8Average contacts per company
1-10Median size (employees)
10.9%Largest-city concentration · New York
Sep 19, 2026Page data refreshed

Companies by employee count

1-10
77
11-50
34
51-200
7
10001+
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 119 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among cognitive enhancement device companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “cognitive enhancement device companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names cognitive enhancement device companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among cognitive enhancement device companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 272 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names cognitive enhancement device companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many cognitive enhancement device companies are there based in the United States?

RevenueBase identified 119 cognitive enhancement device companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Linus Health, headquartered in Boston, tops this list with the largest team on record.

Which city has the most cognitive enhancement device companies?

New York leads with 13 headquartered companies, followed by San Francisco (10) and Los Angeles (5).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 272 verified decision-maker contacts tracked across these 119 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.