Company lists · Data refreshed September 2026

Top 25 Clinical trial modeling companies based in the United States

RevenueBase identified 686 clinical trial modeling companies headquartered in the United States as of September 2026 and tracks 62,816 professional contacts across them, including 30,841 with verified work emails. San Francisco is the largest hub.

This list covers clinical trial modeling companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 16, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 16, 2026 86% judged on-target in blind review
686Companies
62,816Contacts tracked
30,841Verified emails
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The 25 largest clinical trial modeling companies based in the United States

Ranked by team size
Top 25 of 686 clinical trial modeling companies based in the United States, ranked by team size, largest first. Data refreshed Sep 16, 2026. RevenueBase Smart Search rates how each company's information relates to clinical trial modeling companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceWaltham, MA, United StatesHQ checked Sep 16, 202610001+20,530 contacts →

Partial evidence

“The PPD™ clinical research business of Thermo Fisher Scientific, the world leader in serving science, enables customers to accelerate innovation and drug development through…”

Source: RevenueBase Database · checked Sep 16, 2026
2Partial evidenceResearch Triangle Park, NC, United StatesHQ checked Sep 16, 202610001+10,632 contacts →

Partial evidence

“Fortrea (Nasdaq: FTRE) is a leading global clinical research organization (CRO) dedicated to providing innovative clinical development solutions to the life sciences industry.”

Source: RevenueBase Database · checked Sep 16, 2026
3Strong evidenceResearch Triangle Park, NC, United StatesHQ checked Sep 16, 20261,001-5,0003,440 contacts →

Strong evidence

“Worldwide Clinical Trials (Worldwide) is a global CRO serving development-driven biopharmaceutical companies, with more than 4,400 professionals operating across more than 70…”

Source: RevenueBase Database · checked Sep 16, 2026
4Partial evidenceMorrisville, NC, United StatesHQ checked Sep 16, 20261,001-5,0002,584 contacts →

Partial evidence

“Premier Research International LLC (Premier) is a global leader in clinical research and consulting services with expertise in driving an efficient and effective path to market…”

Source: RevenueBase Database · checked Sep 16, 2026
5Partial evidenceBlue Bell, PA, United StatesHQ checked Sep 16, 20261,001-5,0002,083 contacts →

Partial evidence

“For 25+ years, Signant Health has been pioneering solutions and methodologies that propel clinical research programs toward regulatory success.”

Source: RevenueBase Database · checked Sep 16, 2026
6Partial evidenceBethesda, MD, United StatesHQ checked Sep 16, 20261,001-5,0001,781 contacts →

Partial evidence

“Precision for Medicine is an industry-leading global clinical research services organization, purpose-built to improve the clinical research and development process for new…”

Source: RevenueBase Database · checked Sep 16, 2026
7Strong evidenceCambridge, MA, United StatesHQ checked Sep 16, 20261,001-5,0001,580 contacts →

Strong evidence

“Cytel is the world’s leading data-science CRO, driving advancements in human health through robust analytics and innovative clinical trial software.”

Source: RevenueBase Database · checked Sep 16, 2026
8Strong evidenceConshohocken, PA, United StatesHQ checked Sep 16, 20261,001-5,0001,255 contacts →

Strong evidence

“Suvoda is a global clinical trial technology company, now strengthened by our merger with Greenphire.”

Source: RevenueBase Database · checked Sep 16, 2026
9Partial evidenceLincoln, NE, United StatesHQ checked Sep 16, 20261,001-5,0001,080 contacts →

Partial evidence

“Celerion, a leader in early clinical research, delivers Applied Translational Medicine.”

Source: RevenueBase Database · checked Sep 16, 2026
10Partial evidenceCanton, MI, United StatesHQ checked Sep 16, 2026501-1,000876 contacts →

Partial evidence

“MMS Holdings (MMS) is an award-winning, data-focused clinical research organization (CRO) that supports the pharmaceutical and biotech industries with a proven, scientific…”

Source: RevenueBase Database · checked Sep 16, 2026
11Partial evidenceSalt Lake City, UT, United StatesHQ checked Sep 16, 20261,001-5,000847 contacts →

Partial evidence

“CenExel is a leading integrated, wholly owned, nationwide clinical research site network comprised of 18 Centers of Excellence in major metropolitan areas across the U.”

Source: RevenueBase Database · checked Sep 16, 2026
12Partial evidenceRaleigh, NC, United StatesHQ checked Sep 16, 20261,001-5,000758 contacts →

Partial evidence

“Caidya is a multi-therapeutic clinical research organization (CRO) serving innovators worldwide.”

Source: RevenueBase Database · checked Sep 16, 2026
13Strong evidenceRaleigh, NC, United StatesHQ checked Sep 16, 2026501-1,000632 contacts →

Strong evidence

Clinical trials are designed around endpoints, but it’s the beginning that sets them up for success-including selecting the best RTSM partner for continuous and flexible support…”

Source: RevenueBase Database · checked Sep 16, 2026
14Strong evidenceHouston, TX, United StatesHQ checked Sep 16, 2026501-1,000590 contacts →

Strong evidence

“DM Clinical Research is a network of clinical trial investigator sites with headquarters based out of Houston, Texas.”

Source: RevenueBase Database · checked Sep 16, 2026
15Strong evidenceNew York, NY, United StatesHQ checked Sep 16, 2026501-1,000475 contacts →

Strong evidence

“At Citeline (a Norstella company), we are a global leader in clinical trial intelligence, data, and insights for the life sciences and pharmaceutical industries.”

Source: RevenueBase Database · checked Sep 16, 2026
16Indirect evidenceSan Diego, CA, United StatesHQ checked Sep 16, 20261,001-5,000441 contacts →

Indirect evidence

“Crown Bioscience, a JSR Life Sciences company, is a global contract research organization (CRO) providing discovery, preclinical, and translational platforms to advance oncology…”

Source: RevenueBase Database · checked Sep 16, 2026
17Indirect evidenceCambridge, MA, United StatesHQ checked Sep 16, 2026201-500370 contacts →

Indirect evidence

“nference leverages the top academic minds, world-class researchers, and real-time access to multimodal, patient-level data to accelerate drug development innovation, generate…”

Source: RevenueBase Database · checked Sep 16, 2026
18Strong evidenceSan Jose, CA, United StatesHQ checked Sep 16, 2026201-500229 contacts →

Strong evidence

“Since 2005, KlinEra has partnered with some of the largest pharmaceutical, biotech and device companies, providing innovative and customized clinical trial and research services.”

Source: RevenueBase Database · checked Sep 16, 2026
19Partial evidenceAventura, FL, United StatesHQ checked Sep 16, 2026201-500225 contacts →

Partial evidence

“Biorasi is a global clinical research organization (CRO) that delivers speed-to-market strategies for small to midsized biotech and biopharma sponsors.”

Source: RevenueBase Database · checked Sep 16, 2026
20Strong evidenceNew York, United StatesHQ checked Sep 16, 202651-200205 contacts →

Strong evidence

“Our mission at Lindus Health is to accelerate clinical trials, so patients can benefit from new treatments sooner.”

Source: RevenueBase Database · checked Sep 16, 2026
21Partial evidenceDenver, CO, United StatesHQ checked Sep 16, 20261,001-5,000201 contacts →

Partial evidence

“EmVenio Clinical Research, a Professional Case Management subsidiary, operates from U.S.”

Source: RevenueBase Database · checked Sep 16, 2026
22Indirect evidenceMalvern, PA, United StatesHQ checked Sep 16, 2026201-500199 contacts →

Indirect evidence

“Our mission: To accelerate the availability of new, life-changing therapies for patients by partnering with global pharmaceutical companies to improve the quality and execution of…”

Source: RevenueBase Database · checked Sep 16, 2026
23Strong evidenceBakersfield, CA, United StatesHQ checked Sep 16, 202651-200192 contacts →

Strong evidence

“CBCC Global Research is a full service clinical contract research organization serving a wide spectrum of clinical research services including Phase II-IV clinical trials…”

Source: RevenueBase Database · checked Sep 16, 2026
24Partial evidenceDurham, NC, United StatesHQ checked Sep 16, 2026201-500182 contacts →

Partial evidence

“Simulations Plus is a leading provider of modeling and simulation software and consulting services supporting drug discovery, development research, and regulatory submissions.”

Source: RevenueBase Database · checked Sep 16, 2026
25Strong evidenceAmherst, NY, United StatesHQ checked Sep 16, 202651-200171 contacts →

Strong evidence

“Frontier Science is an independent not-for-profit organization with proven expertise in the design, conduct, analysis, and reporting of clinical trials and observational studies.”

Source: RevenueBase Database · checked Sep 16, 2026

Showing 25 of 686 clinical trial modeling companies based in the United States

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Clinical trial modeling companies based in the United States at a glance

As of Sep 16, 2026
49.1%Verified-email coverage
91.6Average contacts per company
11-50Median size (employees)
3.2%Largest-city concentration · San Francisco
Sep 16, 2026Page data refreshed

Companies by employee count

1-10
279
11-50
256
51-200
92
201-500
27
501-1,000
8
1,001-5,000
17
10001+
4

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 686 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among clinical trial modeling companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “clinical trial modeling companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names clinical trial modeling companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among clinical trial modeling companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 30,841 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 16, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names clinical trial modeling companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many clinical trial modeling companies are there based in the United States?

RevenueBase identified 686 clinical trial modeling companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

PPD, headquartered in Waltham, tops this list with the largest team on record.

Which city has the most clinical trial modeling companies?

San Francisco leads with 22 headquartered companies, followed by Boston (20) and San Diego (19).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 30,841 verified decision-maker contacts tracked across these 686 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 16, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.