Company lists · Data refreshed August 2026

Top 25 Clinical trial matching software companies based in the United States

RevenueBase identified 516 clinical trial matching software companies headquartered in the United States as of August 2026 and tracks 20,056 professional contacts across them, including 9,903 with verified work emails and 6,685 with mobile numbers. San Francisco is the largest hub.

This list covers clinical trial matching software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed August 31, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase Smart Search rating on every row Refreshed Aug 31, 2026 86% judged on-target in blind review
516Companies
20,056Contacts tracked
9,903Verified emails
6,685Mobile numbers
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The 25 largest clinical trial matching software companies based in the United States

Ranked by team size
Top 25 of 516 clinical trial matching software companies based in the United States, ranked by team size, largest first. Data refreshed Aug 31, 2026. RevenueBase Smart Search rates how each company's information relates to clinical trial matching software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Strong evidenceBoston, MA, United States1,001-5,0002,688 contacts →

Strong evidence

“Medidata is powering smarter treatments and healthier people through digital solutions to support clinical trials.”

Source: RevenueBase Database · checked Aug 31, 2026
2Partial evidenceBlue Bell, PA, United States1,001-5,0002,078 contacts →

Partial evidence

“For 25+ years, Signant Health has been pioneering solutions and methodologies that propel clinical research programs toward regulatory success.”

Source: RevenueBase Database · checked Aug 31, 2026
3Partial evidenceCambridge, MA, United States1,001-5,0001,763 contacts →

Partial evidence

“Precision for Medicine is an industry-leading global clinical research services organization, purpose-built to improve the clinical research and development process for new…”

Source: RevenueBase Database · checked Aug 31, 2026
4Strong evidencePortland, OR, United States1,001-5,0001,223 contacts →

Strong evidence

“Suvoda is a global clinical trial technology company, now strengthened by our merger with Greenphire.”

Source: RevenueBase Database · checked Aug 31, 2026
5Partial evidenceNew York, NY, United States501-1,000584 contacts →

Partial evidence

“We are committed to providing sustainable and scalable solutions for your clinical research and bioinformatics needs.”

Source: RevenueBase Database · checked Aug 31, 2026
6Indirect evidenceHorsham, PA, United States1,001-5,000565 contacts →

Indirect evidence

“Accelerated Enrollment Solutions (AES) is now Trialmed.”

Source: RevenueBase Database · checked Aug 31, 2026
7Indirect evidenceMansfield, MA, United States201-500467 contacts →

Indirect evidence

“eClinical Solutions’ industry-leading data & analytics platform, elluminate®, and biometrics services experts help biopharma researchers at large, mid-size, and emerging life…”

Source: RevenueBase Database · checked Aug 31, 2026
8Strong evidencePortland, OR, United States201-500389 contacts →

Strong evidence

“4G Clinical’s suite of innovative RTSM and clinical supply optimization software provides the right-sized support for any phase or trial complexity.”

Source: RevenueBase Database · checked Aug 31, 2026
9Partial evidenceCoral Gables, FL, United States501-1,000388 contacts →

Partial evidence

“Sitero is a next-generation, site-focused clinical research organization (CRO) for life sciences and institutional research organizations that helps get treatments to market safer…”

Source: RevenueBase Database · checked Aug 31, 2026
10Indirect evidenceRaleigh, NC, United States501-1,000349 contacts →

Indirect evidence

“Medable's mission is to get effective therapies to patients faster.”

Source: RevenueBase Database · checked Aug 31, 2026
11Strong evidenceAtlanta, GA, United States201-500295 contacts →

Strong evidence

“Florence is a purpose-built platform that connects sponsors and sites to accelerate clinical trials, improve operational capacity, and reduce risk.”

Source: RevenueBase Database · checked Aug 31, 2026
12Strong evidenceAustin, TX, United States201-500257 contacts →

Strong evidence

“Elligo Health Research is an integrated research organization founded to bridge the gap between cutting-edge clinical trials and the patients who need them-an idea that sparked…”

Source: RevenueBase Database · checked Aug 31, 2026
13Indirect evidenceFranklin, TN, United States201-500190 contacts →

Indirect evidence

“ObjectiveHealth is a leading integrated research provider partnering with physicians and healthcare organizations to establish advanced infrastructure for research programs.”

Source: RevenueBase Database · checked Aug 31, 2026
14Indirect evidenceBoston, MA, United States201-500189 contacts →

Indirect evidence

“OneStudyTeam, a member of the Reify Health portfolio, provides the cloud-based platform StudyTeam to accelerate the development of new and life-saving therapies.”

Source: RevenueBase Database · checked Aug 31, 2026
15Partial evidenceNew York, NY, United States51-200176 contacts →

Partial evidence

“SiteRx is building next-generation CNS infrastructure that connects doctors, patients, and pharma to bring clinical research into everyday care.”

Source: RevenueBase Database · checked Aug 31, 2026
16Strong evidenceHauppauge, NY, United States51-200172 contacts →

Strong evidence

Clinical Trial Media (CTM) is the largest full-service global patient enrollment organization, with three decades of experience supporting pharmaceutical and biotechnology…”

Source: RevenueBase Database · checked Aug 31, 2026
17Indirect evidenceWaltham, MA, United States201-500168 contacts →

Indirect evidence

“Sycamore Informatics provides the life science industry's premier Enterprise Data Science Application Suite.”

Source: RevenueBase Database · checked Aug 31, 2026
18Partial evidenceNewtown Square, PA, United States201-500166 contacts →

Partial evidence

“Atorus delivers far-reaching insights and efficiencies from your clinical data, producing robust intelligence that fuels decisions, fast.”

Source: RevenueBase Database · checked Aug 31, 2026
19Strong evidenceHenderson, NV, United States201-500157 contacts →

Strong evidence

“M3 Wake Research is a premier clinical trial network that has been conducting studies since 1984.”

Source: RevenueBase Database · checked Aug 31, 2026
20Partial evidenceCambridge, MA, United States51-200150 contacts →

Partial evidence

“Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes.”

Source: RevenueBase Database · checked Aug 31, 2026
21Indirect evidenceSan Francisco, CA, United States51-200137 contacts →

Indirect evidence

“It’s time to reimagine what’s possible in healthcare.”

Source: RevenueBase Database · checked Aug 31, 2026
22Partial evidenceEden Prairie, MN, United States51-200137 contacts →

Partial evidence

“WCG ThreeWire is a global, full-service patient recruitment provider that partners with pharmaceutical, biotech companies, and clinical research organizations to improve the…”

Source: RevenueBase Database · checked Aug 31, 2026
23Partial evidencePrinceton, NJ, United States201-500136 contacts →

Partial evidence

“Veranex brings together best-in-class expertise in product design and engineering, medical device evaluation, clinical development, data management, regulatory, and market access…”

Source: RevenueBase Database · checked Aug 31, 2026
24Indirect evidenceNew York, NY, United States51-200135 contacts →

Indirect evidence

“Our mission is to enable earlier and better access to all possible treatment options.”

Source: RevenueBase Database · checked Aug 31, 2026
25Indirect evidenceWalnut Creek, CA, United States51-200130 contacts →

Indirect evidence

“Hawthorne Health is the leading community site network, with 75+ locations across the U.S.”

Source: RevenueBase Database · checked Aug 31, 2026

Showing 25 of 516 clinical trial matching software companies based in the United States

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Clinical trial matching software companies based in the United States at a glance

As of Aug 31, 2026
49.4%Verified-email coverage
33.3%Mobile-number coverage
38.9Average contacts per company
11-50Median size (employees)
5.8%Largest-city concentration · San Francisco
Aug 31, 2026Page data refreshed

Companies by employee count

1-10
204
11-50
205
51-200
72
201-500
19
501-1,000
5
1,001-5,000
9
10001+
1

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among clinical trial matching software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “clinical trial matching software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names clinical trial matching software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among clinical trial matching software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 9,903 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on August 31, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Clinical trial matching software companies by metro

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names clinical trial matching software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many clinical trial matching software companies are there based in the United States?

RevenueBase identified 516 clinical trial matching software companies headquartered in the United States as of August 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Medidata Solutions, headquartered in Boston, tops this list with the largest team on record.

Which city has the most clinical trial matching software companies?

San Francisco leads with 30 headquartered companies, followed by Boston (28) and New York (23).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 9,903 verified decision-maker contacts tracked across these 516 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on August 31, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.