Company lists · Data refreshed September 2026

Top 25 Clinical stage biotech companies based in South San Francisco, United States

RevenueBase identified 40 clinical stage biotech companies headquartered in South San Francisco, United States as of September 2026 and tracks 19,746 professional contacts across them, including 9,230 with verified work emails. Cambridge is the largest hub.

This list covers clinical stage biotech companies headquartered in South San Francisco, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 16, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 16, 2026 86% judged on-target in blind review
40Companies
19,746Contacts tracked
9,230Verified emails
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The 25 largest clinical stage biotech companies based in South San Francisco, United States

Ranked by team size
Top 25 of 40 clinical stage biotech companies based in South San Francisco, United States, ranked by team size, largest first. Data refreshed Sep 16, 2026. RevenueBase Smart Search rates how each company's information relates to clinical stage biotech companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202610001+17,217 contacts →

Indirect evidence

“About Genentech We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions.”

Source: RevenueBase Database · checked Sep 16, 2026
2Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202651-200291 contacts →

Partial evidence

“Rigel Pharmaceuticals, Inc, is a biotechnology company dedicated to discovering, developing and providing novel small molecule drugs that significantly improve the lives of…”

Source: RevenueBase Database · checked Sep 16, 2026
3Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 2026201-500282 contacts →

Indirect evidence

“Sutro Biopharma, Inc, is relentlessly focused on the discovery and development of precisely designed cancer therapeutics to transform what science can do for patients.”

Source: RevenueBase Database · checked Sep 16, 2026
4Strong evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202651-200192 contacts →

Strong evidence

“We are a late-stage clinical biotechnology company with a mission to make degenerative brain disorders history.”

Source: RevenueBase Database · checked Sep 16, 2026
5Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-50125 contacts →

Indirect evidence

“At Alumis, our goal is to significantly improve the lives of patients by replacing broad immunosuppression with targeted therapies.”

Source: RevenueBase Database · checked Sep 16, 2026
6Strong evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202651-200123 contacts →

Strong evidence

“RAPT is a clinical-stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing novel therapies for patients living with inflammatory…”

Source: RevenueBase Database · checked Sep 16, 2026
7Strong evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202651-200119 contacts →

Strong evidence

“Tenaya Therapeutics is a clinical stage biotechnology company.”

Source: RevenueBase Database · checked Sep 16, 2026
8Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-50116 contacts →

Indirect evidence

“NGM Bio is a biopharmaceutical company focused on discovering and developing novel, life-changing medicines for people whose health and lives have been disrupted by disease.”

Source: RevenueBase Database · checked Sep 16, 2026
9Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202651-200100 contacts →

Indirect evidence

“CytomX Therapeutics, Inc.”

Source: RevenueBase Database · checked Sep 16, 2026
10Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-5043 contacts →

Partial evidence

“Our mission is to cure age-related disease by moving successful therapeutics toward clinical trials within months, not years.#CreatingTime”

Source: RevenueBase Database · checked Sep 16, 2026
11Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202651-20036 contacts →

Indirect evidence

“RemeGen Biosciences is a biopharmaceutical company, focusing on the discovery and development of innovative medicines for the treatment of cancer and autoimmune diseases, based in…”

Source: RevenueBase Database · checked Sep 16, 2026
12Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-5034 contacts →

Indirect evidence

“Smash the mutants”

Source: RevenueBase Database · checked Sep 16, 2026
13Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-5031 contacts →

Indirect evidence

“Lyterian Therapeutics derives its name from the Greek word λυτήριος or lutḗrios, that defines the termination, healing, or end of disease.”

Source: RevenueBase Database · checked Sep 16, 2026
14Strong evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202651-20028 contacts →

Strong evidence

“Calithera Biosciences is a clinical-stage biopharmaceutical company pioneering the discovery and development of targeted therapies that disrupt cellular metabolic pathways to…”

Source: RevenueBase Database · checked Sep 16, 2026
15Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-5020 contacts →

Indirect evidence

“Founded by life sciences venture capital firm ATP and renowned scientists at the University of California San Francisco (UCSF), Nine Square is uniting machine learning-enabled…”

Source: RevenueBase Database · checked Sep 16, 2026
16Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 20261-1018 contacts →

Indirect evidence

“At Apertor we have developed a new class of therapeutics to address one of the toughest challenges in drug discovery, selective disruption of disease-causing protein-protein…”

Source: RevenueBase Database · checked Sep 16, 2026
17Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-5017 contacts →

Partial evidence

“R2M Pharma is a fast growing biotechnology research organization devoted to the discovery of high quality small molecules preclinical development compounds for the treatment of…”

Source: RevenueBase Database · checked Sep 16, 2026
18Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-5015 contacts →

Partial evidence

“Initial Therapeutics is discovering and developing a new class of small-molecule medicines designed to halt pathogenic protein formation in the earliest stages.”

Source: RevenueBase Database · checked Sep 16, 2026
19Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-5013 contacts →

Indirect evidence

“Pragma Bio exists to find cures for undruggable immunological disorders.”

Source: RevenueBase Database · checked Sep 16, 2026
20Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-5012 contacts →

Partial evidence

“QLSF Biotherapeutics is an innovative immuno-oncology biotech startup in South San Francisco.”

Source: RevenueBase Database · checked Sep 16, 2026
21Strong evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 20261-1010 contacts →

Strong evidence

“Silver Creek is a clinical-stage biopharmaceutical company with a mission to deliver life-changing medicines to patients in need.”

Source: RevenueBase Database · checked Sep 16, 2026
22Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 20261-109 contacts →

Partial evidence

“Synlico is a patient-native causal AI biotech building a generative causal discovery and inference platform SynCausal(TM) that learns directed gene causal graphs from primary…”

Source: RevenueBase Database · checked Sep 16, 2026
23Strong evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 20261-107 contacts →

Strong evidence

“IgGenix is a clinical-stage, venture backed biotechnology company founded on breakthrough advances in Steve Quake’s laboratory at Stanford in collaboration with allergy clinician…”

Source: RevenueBase Database · checked Sep 16, 2026
24Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-506 contacts →

Indirect evidence

“DC3 Therapeutics is a full-service CRO based in South San Francisco, CA.”

Source: RevenueBase Database · checked Sep 16, 2026
25Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202611-503 contacts →

Indirect evidence

“Serotiny is a therapeutic discovery company that designs new genes for next generation cell & gene therapies.”

Source: RevenueBase Database · checked Sep 16, 2026

Showing 25 of 40 clinical stage biotech companies based in South San Francisco, United States

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Clinical stage biotech companies based in South San Francisco, United States at a glance

As of Sep 16, 2026
46.7%Verified-email coverage
493.6Average contacts per company
11-50Median size (employees)
240.0%Largest-city concentration · Cambridge
Sep 16, 2026Page data refreshed

Companies by employee count

1-10
11
11-50
15
51-200
10
201-500
1
501-1,000
1
10001+
1

Email recency for this list is measured across the whole United States list rather than for South San Francisco, so it is reported there. Company counts and contact totals on this page are exact for South San Francisco, over 40 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among clinical stage biotech companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in South San Francisco, United States whose own description of what they do matches “clinical stage biotech companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names clinical stage biotech companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among clinical stage biotech companies, and records with no verified work email. Companies headquartered outside South San Francisco are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 9,230 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 16, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names clinical stage biotech companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many clinical stage biotech companies are there based in South San Francisco, United States?

RevenueBase identified 40 clinical stage biotech companies headquartered in South San Francisco, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Genentech, headquartered in South San Francisco, tops this list with the largest team on record.

Which city has the most clinical stage biotech companies?

Cambridge leads with 96 headquartered companies, followed by San Diego (96) and Boston (86).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 9,230 verified decision-maker contacts tracked across these 40 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 16, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.