Company lists · Data refreshed September 2026

Top 25 Clinical decision support system companies based in the United States

RevenueBase identified 91 clinical decision support system companies headquartered in the United States as of September 2026 and tracks 3,978 professional contacts across them, including 1,498 with verified work emails. Boston is the largest hub.

This list covers clinical decision support system companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 16, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 16, 2026 86% judged on-target in blind review
91Companies
3,978Contacts tracked
1,498Verified emails
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The 25 largest clinical decision support system companies based in the United States

Ranked by team size
Top 25 of 91 clinical decision support system companies based in the United States, ranked by team size, largest first. Data refreshed Sep 16, 2026. RevenueBase Smart Search rates how each company's information relates to clinical decision support system companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceNorristown, PA, United StatesHQ checked Sep 16, 20261,001-5,0001,010 contacts →

Partial evidence

“MRO is The Single Source for Smarter Data™-driving a new era of clinical data intelligence where data is connected, structured, and transformed into actionable insights.”

Source: RevenueBase Database · checked Sep 16, 2026
2Strong evidenceSeattle, WA, United StatesHQ checked Sep 16, 2026201-500516 contacts →

Strong evidence

“MCG Health, part of the Hearst Health network, develops evidence-based guidelines and artificial intelligence solutions that are the source of truth for clinical decision-making.”

Source: RevenueBase Database · checked Sep 16, 2026
3Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 2026201-500415 contacts →

Partial evidence

“FDB (First Databank) creates and integrates the world’s most trusted drug knowledge that, in partnership with our customers, illuminates critical healthcare decisions.”

Source: RevenueBase Database · checked Sep 16, 2026
4Strong evidenceWaltham, MA, United StatesHQ checked Sep 16, 20265,001-10,000242 contacts →

Strong evidence

“UpToDate® is a leading clinical decision support solution, trusted by clinicians and healthcare enterprises worldwide to help make confident, evidence-based decisions.”

Source: RevenueBase Database · checked Sep 16, 2026
5Indirect evidenceRockville, MD, United StatesHQ checked Sep 16, 202651-200145 contacts →

Indirect evidence

“Digital Infuzion is a software and health care IT company.”

Source: RevenueBase Database · checked Sep 16, 2026
6Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 16, 202651-200114 contacts →

Indirect evidence

“At Carta Healthcare, we believe high-quality data is the foundation for better healthcare outcomes.”

Source: RevenueBase Database · checked Sep 16, 2026
7Strong evidenceRochester, NY, United StatesHQ checked Sep 16, 202651-20096 contacts →

Strong evidence

“At VisualDx, we’re a team of physicians, educators, and technologists headquartered in Rochester, NY with a mission to make clinical decision-making faster, easier, and more…”

Source: RevenueBase Database · checked Sep 16, 2026
8Indirect evidenceSan Diego, CA, United StatesHQ checked Sep 16, 202651-20091 contacts →

Indirect evidence

“Cognitive, an information technology and software engineering professional services company, is dedicated to one thing: elevating the quality, speed and delivery of today’s US…”

Source: RevenueBase Database · checked Sep 16, 2026
9Strong evidenceDedham, MA, United StatesHQ checked Sep 16, 202651-20063 contacts →

Strong evidence

“is a care optimization, decision support and provider enablement company powered by big data, AI-powered analytics, expert insights and point of care technology solutions.”

Source: RevenueBase Database · checked Sep 16, 2026
10Strong evidenceNashville, TN, United StatesHQ checked Sep 16, 202611-5061 contacts →

Strong evidence

“EvidenceCare is a physician-centered clinical decision support platform that empowers better care decisions throughout the patient’s hospital care journey with the vision that…”

Source: RevenueBase Database · checked Sep 16, 2026
11Strong evidenceWilmington, DE, United StatesHQ checked Sep 16, 202651-20060 contacts →

Strong evidence

“Amalgam Rx empowers patients and providers to make the best decisions possible-within clinical workflows and everyday life.”

Source: RevenueBase Database · checked Sep 16, 2026
12Partial evidenceRedwood City, CA, United StatesHQ checked Sep 16, 202651-20060 contacts →

Partial evidence

“MedExpert is The Medical Decision Company.”

Source: RevenueBase Database · checked Sep 16, 2026
13Partial evidenceEdison, NJ, United StatesHQ checked Sep 16, 2026201-50053 contacts →

Partial evidence

“Vital Decisions is now Evolent.”

Source: RevenueBase Database · checked Sep 16, 2026
14Partial evidenceLewisville, TX, United StatesHQ checked Sep 16, 202611-5050 contacts →

Partial evidence

“When your system goes down, we lift you up.”

Source: RevenueBase Database · checked Sep 16, 2026
15Indirect evidenceNew York, NY, United StatesHQ checked Sep 16, 202611-5046 contacts →

Indirect evidence

“MDCalc is entering its 20th year.”

Source: RevenueBase Database · checked Sep 16, 2026
16Indirect evidenceCupertino, United StatesHQ checked Sep 16, 202611-5045 contacts →

Indirect evidence

“Evolko is simple, easy to use and designed for specialists.”

Source: RevenueBase Database · checked Sep 16, 2026
17Strong evidenceLansdale, VA, United StatesHQ checked Sep 16, 202611-5044 contacts →

Strong evidence

“VivproAI offers a revolutionary biointelligence software platform and innovative services to make evidence-based clinical, regulatory, and business decisions at lightning speed…”

Source: RevenueBase Database · checked Sep 16, 2026
18Partial evidencePhoenix, AZ, United StatesHQ checked Sep 16, 202611-5042 contacts →

Partial evidence

“Since 1994, PEPID has been a leading developer of clinical and drug information resources and mobile apps for healthcare providers, hospitals and schools.”

Source: RevenueBase Database · checked Sep 16, 2026
19Partial evidenceMiami, FL, United StatesHQ checked Sep 16, 202611-5023 contacts →

Partial evidence

“Real-time clinical reasoning built around your practice.”

Source: RevenueBase Database · checked Sep 16, 2026
20Indirect evidenceEl Cerrito, CA, United StatesHQ checked Sep 16, 202611-5021 contacts →

Indirect evidence

“WE ARE DOCTORS.”

Source: RevenueBase Database · checked Sep 16, 2026
21Partial evidencePlymouth, MI, United StatesHQ checked Sep 16, 202611-5020 contacts →

Partial evidence

“We are a bioinformatics-based precision medicine platform company translating patient-specific and population-based medical big data into novel pharmacological clinical treatment…”

Source: RevenueBase Database · checked Sep 16, 2026
22Partial evidenceDenver, CO, United StatesHQ checked Sep 16, 202611-5019 contacts →

Partial evidence

“cliexa is the clinical reasoning layer of healthcare.”

Source: RevenueBase Database · checked Sep 16, 2026
23Strong evidenceSan Diego, CA, United StatesHQ checked Sep 16, 202611-5017 contacts →

Strong evidence

“CureMatch is a leader in AI-based precision medicine, digital decision support solutions that support cancer treatment.”

Source: RevenueBase Database · checked Sep 16, 2026
24Strong evidenceSperryville, VA, United StatesHQ checked Sep 16, 202611-5015 contacts →

Strong evidence

“We support healthcare providers and improve patient outcomes by providing concise, reliable, and accessible clinical guidance and technologies that support treatment…”

Source: RevenueBase Database · checked Sep 16, 2026
25Indirect evidenceSeattle, WA, United StatesHQ checked Sep 16, 202611-5014 contacts →

Indirect evidence

“Tactuum is a digital consulting firm, specializing in digital tools and services that enrich the wellbeing of people.”

Source: RevenueBase Database · checked Sep 16, 2026

Showing 25 of 91 clinical decision support system companies based in the United States

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Clinical decision support system companies based in the United States at a glance

As of Sep 16, 2026
37.7%Verified-email coverage
43.7Average contacts per company
11-50Median size (employees)
4.4%Largest-city concentration · Boston
Sep 16, 2026Page data refreshed

Companies by employee count

1-10
39
11-50
33
51-200
12
201-500
4
501-1,000
1
1,001-5,000
1
5,001-10,000
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 91 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among clinical decision support system companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “clinical decision support system companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names clinical decision support system companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among clinical decision support system companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 1,498 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 16, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names clinical decision support system companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many clinical decision support system companies are there based in the United States?

RevenueBase identified 91 clinical decision support system companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

MRO, headquartered in Norristown, tops this list with the largest team on record.

Which city has the most clinical decision support system companies?

Boston leads with 4 headquartered companies, followed by San Diego (4) and San Francisco (4).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,498 verified decision-maker contacts tracked across these 91 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 16, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.