Company lists · Data verified August 2026
Top 25 Clinical decision support software companies based in the United States
There are 119 clinical decision support software companies headquartered in the United States (RevenueBase, August 2026). RevenueBase tracks 3,141 professional contacts across them, including 1,104 with verified work emails and 1,426 with mobile numbers. Boston is the largest hub.
This list covers clinical decision support software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Data current as of August 28, 2026.
The 25 largest clinical decision support software companies based in the United States
Ranked by team size| # | Company | Verified emails |
|---|---|---|
| 1 |  MCG Health | 243 |
| 2 |  Uptodate | 82 |
| 3 |  Digital Infuzion | 85 |
| 4 |  Clinical Architecture | 84 |
| 5 |  Regard | 22 |
| 6 |  Visualdx | 55 |
| 7 |  Cognitive Medical Systems, INC | 2 |
| 8 |  Intelligentdx | 28 |
| 9 |  Amalgam RX | 35 |
| 10 |  Evidencecare | 37 |
| 11 |  Ipeople Healthcare, An Rldatix Company | 40 |
| 12 |  Vital Decisions NOW Evolent | 16 |
| 13 |  Inspirata | 32 |
| 14 | Evolko Systems INC | 18 |
| 15 |  Quantros | 3 |
| 16 |  Vivpro Corp | 33 |
| 17 |  Mdcalc | 29 |
| 18 |  PEPID | 12 |
| 19 |  Cedaron Medical | 23 |
| 20 |  SOFYA | 4 |
| 21 |  Medone Systems, INC | 16 |
| 22 |  Softbir | 8 |
| 23 |  Care Everywhere | 14 |
| 24 |  Cliexa | 9 |
| 25 |  Elimu Informatics | 10 |
Showing 25 of 119 clinical decision support software companies based in the United States
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Clinical decision support software companies based in the United States at a glance
As of Aug 28, 2026Companies by employee count
Clinical decision support software companies by metro
| Metro | Companies |
|---|---|
| Clinical decision support software companies in Boston | 7 |
| Clinical decision support software companies in San Diego | 4 |
| Clinical decision support software companies in New York | 3 |
| Clinical decision support software companies in San Francisco | 3 |
| Clinical decision support software companies in Rochester | 2 |
| Clinical decision support software companies in Cambridge | 2 |
| Clinical decision support software companies in Houston | 2 |
| Clinical decision support software companies in Seattle | 2 |
How this list was built
- Source
- The RevenueBase company graph: 21.3 million companies and 398.9 million professional contacts resolved from primary sources.
- Inclusion
- Companies whose own business descriptions match “clinical decision support software companies”, with match quality audited by blind human judging, and headquartered in the United States.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Contact records re-verify on a rolling cadence; 8 contacts on this list were re-verified in the last 30 days.
- Refresh
- Lists are refreshed periodically as the underlying company graph is re-verified. Last verified Aug 28, 2026.
Frequently asked
How many clinical decision support software companies are there based in the United States?
There are 119 clinical decision support software companies headquartered in the United States as of August 2026 (RevenueBase).
What is the largest company on this list?
MCG Health, headquartered in San Diego, tops this list with the largest team on record.
Which city has the most clinical decision support software companies?
Boston leads with 7 headquartered companies, followed by San Diego (4) and New York (3).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,104 verified decision-maker contacts tracked across these 119 companies.
How current is this list?
The list is refreshed periodically as the underlying company graph is re-verified. It was last verified on August 28, 2026.
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About this data
RevenueBase is a B2B contact data platform. Its company graph covers 21.3 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph, the same data that powers RevenueBase's B2B data products and the free research portal.
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