Company lists · Data refreshed October 2026

Top 25 Chemical synthesis manufacturers based in the United States

RevenueBase identified 356 company matches for chemical synthesis manufacturers associated with the United States as of October 2026 and tracks 9,421 professional contacts across them, including 3,595 with verified work emails. San Diego is the largest hub.

This list covers company matches for chemical synthesis manufacturers associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed October 9, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Oct 9, 2026 How this list was built
356Companies
9,421Contacts tracked
3,595Verified emails
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The 25 largest chemical synthesis manufacturers based in the United States

Ranked by team size
Top 25 of 356 company matches for chemical synthesis manufacturers based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Oct 9, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchParsippany, NJ, United StatesHQ recorded Oct 9, 20261,001-5,000684 contacts →

Exact match

“Every day, AdvanSix employees create chemistries that turn possibilities into solutions.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
2Exact matchRancho Cordova, CA, United StatesHQ recorded Oct 9, 20261,001-5,000552 contacts →

Exact match

“Established in 2019 by SK Inc, SK pharmteco is a global contract development and manufacturing organization (CDMO) with operations across the U.S, Europe, and South Korea.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
3Exact matchIndianapolis, IN, United StatesHQ recorded Oct 9, 2026501-1,000414 contacts →

Exact match

“Every day, our customers bring us their toughest chemistry challenges.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
4Exact matchNew Brunswick, NJ, United StatesHQ recorded Oct 9, 2026201-500243 contacts →

Exact match

“Spectrum Chemical Mfg.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
5Exact matchConcord, OH, United StatesHQ recorded Oct 9, 202651-200236 contacts →

Exact match

“Who we are: On June 9, 2017, Olon S.p.A, a leading Active Pharmaceutical Ingredients (API) contract development and manufacturing organization (CDMO) and Generics supplier…”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
6Exact matchPowell, OH, United StatesHQ recorded Oct 9, 202651-200206 contacts →

Exact match

“We don’t just make chemicals.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
7Exact matchNew Castle, DE, United StatesHQ recorded Oct 9, 202651-200181 contacts →

Exact match

“Adesis Inc.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
8Exact matchNorth Augusta, SC, United StatesHQ recorded Oct 9, 2026501-1,000170 contacts →

Exact match

“As of 1st August 2026, AmbioPharm is now part of CordenPharma.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
9Exact matchBangor, PA, United StatesHQ recorded Oct 9, 2026201-500162 contacts →

Exact match

“BioSpectra Inc.(BSI), is a privately-owned manufacturer of premium pharmaceutical ingredients and bulk, cGMP fine chemicals, in service to many leading BioPharma companies around…”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
10Exact matchRosenberg, TX, United StatesHQ recorded Oct 9, 2026201-500157 contacts →

Exact match

“Extensive chemical synthesis, formulation, manufacturing, and technology expertise.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
11Exact matchEvans City, PA, United StatesHQ recorded Oct 9, 2026201-500149 contacts →

Exact match

“Ascensus Specialties is a chemical company that helps our partners make a difference in the world.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
12Exact matchCincinnati, OH, United StatesHQ recorded Oct 9, 2026201-500149 contacts →

Exact match

“Founded in 1916, The Shepherd Chemical Company is a fourth generation, family owned specialty chemical company dedicated to being our customer’s best co-development partner and…”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
13Exact matchEast Brunswick, NJ, United StatesHQ recorded Oct 9, 2026501-1,000145 contacts →

Exact match

“Apicore LLC, a wholly owned subsidiary of RK Pharma Inc is a leading process R&D and API manufacturing service provider for the worldwide pharmaceutical industry.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
14Exact matchEasley, SC, United StatesHQ recorded Oct 9, 2026201-500139 contacts →

Exact match

“Ortec is a custom chemical manufacturing and research company that helps our customers reach their market goals through our Technical Expertise, Quality Systems, Regulatory…”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
15Exact matchFlorence, KY, United StatesHQ recorded Oct 9, 2026201-500116 contacts →

Exact match

“Camco Chemical brings over 65 years of expertise as a trusted leader in chemical contract manufacturing, contract packaging, and supply chain solutions.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
16Exact matchValdosta, GA, United StatesHQ recorded Oct 9, 202651-200113 contacts →

Exact match

“At CJB Industries, we deliver solutions to your chemical manufacturing challenges.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
17Exact matchSouth Plainfield, NJ, United StatesHQ recorded Oct 9, 202651-200109 contacts →

Exact match

“Founded in 1996 J-STAR Research, Inc.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
18Exact matchSchaumburg, IL, United StatesHQ recorded Oct 9, 202651-200108 contacts →

Exact match

“We are an elite family of companies that solve complex problems for our customers through specialty chemical manufacturing and tolling.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
19Exact matchCoshocton, OH, United StatesHQ recorded Oct 9, 2026201-50099 contacts →

Exact match

“Wiley Companies is an ISO 9001:2015 and FSSC certified custom chemicals and food ingredients manufacturer with facilities in Coshocton, OH, and New Albany, OH.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
20Exact matchPearland, TX, United StatesHQ recorded Oct 9, 202651-20097 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
21Exact matchHouston, TX, United StatesHQ recorded Oct 9, 202651-20093 contacts →

Exact match

“Synsus Private Label Partners is a leading U.S.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
22Exact matchFairfield, OH, United StatesHQ recorded Oct 9, 202651-20090 contacts →

Exact match

“Calvary Industries was founded in 1983 as a chemical compounding supplier and manufacturer.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
23Exact matchGreenville, SC, United StatesHQ recorded Oct 9, 2026201-50089 contacts →

Exact match

“Ethox Chemicals, A Syntha Group Company Founded in 1938 by Fred Wilson, Sr.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
24Exact matchNewtown, PA, United StatesHQ recorded Oct 9, 202651-20081 contacts →

Exact match

“Founded in 2014, SynSmart has made its name in chemistry services for early-stage discovery projects as well as collaborative scale-up and manufacturing support services.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase
25Exact matchHigh Point, NC, United StatesHQ recorded Oct 9, 202651-20080 contacts →

Exact match

“Kao Specialties Americas is a specialty chemical manufacturing company located 243 Woodbine St.”

Recorded in the RevenueBase company graph · Oct 9, 2026 · View company records in RevenueBase

Showing 25 of 356 chemical synthesis manufacturers based in the United States

See the full list, filter by size, metro and specialty, and access 3,595 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Chemical synthesis manufacturers based in the United States at a glance

As of Oct 9, 2026
38.2%Verified-email coverage
26.5Average contacts per company
11-50Median size (employees)
3.9%Largest-city concentration · San Diego
Oct 9, 2026Page data refreshed

Companies by employee count

1-10
121
11-50
118
51-200
82
201-500
19
501-1,000
10
1,001-5,000
4
10001+
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 356 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “chemical synthesis manufacturers” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 3,595 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on October 9, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “chemical synthesis manufacturers”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many chemical synthesis manufacturers are there based in the United States?

RevenueBase identified 356 company matches for chemical synthesis manufacturers associated with the United States as of October 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Advansix tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most chemical synthesis manufacturers?

San Diego leads with 14 company records, followed by Houston (9) and New York (5).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 3,595 professional contacts with verified work emails tracked across these 356 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on October 9, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.