Company lists · Data refreshed September 2026

Top 25 Checkpoint inhibitor manufacturers based in the United States

RevenueBase identified 169 checkpoint inhibitor manufacturers headquartered in the United States as of September 2026 and tracks 5,201 professional contacts across them, including 2,566 with verified work emails. Cambridge is the largest hub.

This list covers checkpoint inhibitor manufacturers headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 16, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 16, 2026 86% judged on-target in blind review
169Companies
5,201Contacts tracked
2,566Verified emails
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The 25 largest checkpoint inhibitor manufacturers based in the United States

Ranked by team size
Top 25 of 169 checkpoint inhibitor manufacturers based in the United States, ranked by team size, largest first. Data refreshed Sep 16, 2026. RevenueBase Smart Search rates how each company's information relates to checkpoint inhibitor manufacturers: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceSeal Beach, CA, United StatesHQ checked Sep 16, 2026501-1,000637 contacts →

Indirect evidence

“Dendreon is a commercial-stage biopharmaceutical company and pioneer in the development of immunotherapy.”

Source: RevenueBase Database · checked Sep 16, 2026
2Indirect evidenceSan Diego, CA, United StatesHQ checked Sep 16, 2026501-1,000591 contacts →

Indirect evidence

“ImmunityBio, Inc.(formerly NantKwest, Inc.) is developing cell and immunotherapy products that are designed to help strengthen each patient’s natural immune system, potentially…”

Source: RevenueBase Database · checked Sep 16, 2026
3Indirect evidenceBoston, MA, United StatesHQ checked Sep 16, 202651-200213 contacts →

Indirect evidence

“AVEO is a commercial-stage, oncology-focused biopharmaceutical company committed to delivering medicines that provide a better life for patients with cancer.”

Source: RevenueBase Database · checked Sep 16, 2026
4Indirect evidenceSeattle, WA, United StatesHQ checked Sep 16, 202651-200205 contacts →

Indirect evidence

“Umoja is developing a new approach to cancer therapy that retools a patient’s immune system in vivo, enhancing the body’s natural capacity to fight cancer.”

Source: RevenueBase Database · checked Sep 16, 2026
5Indirect evidenceCambridge, MA, United StatesHQ checked Sep 16, 202651-200137 contacts →

Indirect evidence

“iTeos Therapeutics is a clinical-stage biopharmaceutical company pioneering the discovery and development of a new generation of immuno-oncology therapeutics for patients.”

Source: RevenueBase Database · checked Sep 16, 2026
6Indirect evidenceSan Diego, CA, United StatesHQ checked Sep 16, 202651-200113 contacts →

Indirect evidence

“Janux is a clinical-stage company developing unique immunotherapies that have the potential to generate tumor-specific immune responses to attack and kill tumors without…”

Source: RevenueBase Database · checked Sep 16, 2026
7Indirect evidenceBothell, WA, United StatesHQ checked Sep 16, 202651-200111 contacts →

Indirect evidence

“Located in Redmond WA, founded in 2014, Systimmune Inc.”

Source: RevenueBase Database · checked Sep 16, 2026
8Indirect evidenceRockville, MD, United StatesHQ checked Sep 16, 202611-5096 contacts →

Indirect evidence

“I-Mab (NASDAQ: IMAB) is a U.S-based, global biotech company, focused on the development of precision immuno-oncology agents for the treatment of cancer.”

Source: RevenueBase Database · checked Sep 16, 2026
9Indirect evidenceCambridge, MA, United StatesHQ checked Sep 16, 202651-20087 contacts →

Indirect evidence

“Repertoire Immune Medicines is a biotechnology company dedicated to creating treatments for diseases based on the power of the human T cell repertoire to eliminate cancer cells…”

Source: RevenueBase Database · checked Sep 16, 2026
10Indirect evidenceLexington, MA, United StatesHQ checked Sep 16, 202611-5077 contacts →

Indirect evidence

“Curis is a publicly-traded biotechnology company (NASDAQ: CRIS) focused on the development of first-in-class and innovative therapeutics or the treatment of cancer.”

Source: RevenueBase Database · checked Sep 16, 2026
11Indirect evidenceSan Diego, CA, United StatesHQ checked Sep 16, 202611-5072 contacts →

Indirect evidence

“Kumquat Biosciences’ vision is to develop innovative therapies to bring about sustainable and life-changing benefits to cancer patients.”

Source: RevenueBase Database · checked Sep 16, 2026
12Indirect evidenceRockville, MD, United StatesHQ checked Sep 16, 202651-20068 contacts →

Indirect evidence

“Based in Rockville, Maryland, OncoC4 is a privately held, late clinical-stage biopharmaceutical company that is actively engaged in the discovery and development of novel…”

Source: RevenueBase Database · checked Sep 16, 2026
13Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202651-20068 contacts →

Indirect evidence

“In 2015, Pionyr Immunotherapeutics embarked on a journey to forge a new path in immuno-oncology for patients in need.”

Source: RevenueBase Database · checked Sep 16, 2026
14Indirect evidenceBoston, MA, United StatesHQ checked Sep 16, 202651-20067 contacts →

Indirect evidence

“Pyxis Oncology is transforming the lives of patients with cancer by advancing our differentiated portfolio of biologics that specifically target tumor cells and overcome immune…”

Source: RevenueBase Database · checked Sep 16, 2026
15Indirect evidenceRedwood City, CA, United StatesHQ checked Sep 16, 202651-20066 contacts →

Indirect evidence

“Bolt Biotherapeutics, Inc, based in the San Francisco Bay Area, is a publicly-traded biotechnology company developing Boltbody™ Immune-stimulating Antibody Conjugates (ISAC), a…”

Source: RevenueBase Database · checked Sep 16, 2026
16Indirect evidenceSeattle, WA, United StatesHQ checked Sep 16, 202651-20061 contacts →

Indirect evidence

“HDT Bio is a vaccine and immunotherapy Biotechnology company developing drugs for immunotherapy of cancers and infectious diseases with next-generation approaches designed to…”

Source: RevenueBase Database · checked Sep 16, 2026
17Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 16, 202651-20058 contacts →

Indirect evidence

“ALX Oncology (Nasdaq: ALXO) is a clinical-stage biotechnology company advancing therapies that boost the immune system to treat cancer and extend patients’ lives.”

Source: RevenueBase Database · checked Sep 16, 2026
18Indirect evidenceWaltham, MA, United StatesHQ checked Sep 16, 202651-20057 contacts →

Indirect evidence

“We know that drug development is both an art and a science.”

Source: RevenueBase Database · checked Sep 16, 2026
19Indirect evidenceBeltsville, MD, United StatesHQ checked Sep 16, 202651-20052 contacts →

Indirect evidence

“NextCure is a clinical-stage biopharmaceutical company committed to discovering and developing novel, first-in-class immunomedicines to treat cancer and other immune-related…”

Source: RevenueBase Database · checked Sep 16, 2026
20Partial evidenceSan Carlos, CA, United StatesHQ checked Sep 16, 202611-5052 contacts →

Partial evidence

“GigaGen, a subsidiary of Grifols, is advancing transformative antibody drugs for immune deficiency, infectious diseases and checkpoint resistant cancers by leveraging…”

Source: RevenueBase Database · checked Sep 16, 2026
21Indirect evidenceBoston, MA, United StatesHQ checked Sep 16, 202611-5051 contacts →

Indirect evidence

“Compass Therapeutics, Inc.”

Source: RevenueBase Database · checked Sep 16, 2026
22Indirect evidenceWatertown, MA, United StatesHQ checked Sep 16, 202611-5049 contacts →

Indirect evidence

“We are an immuno-oncology company advancing a pipeline of next generation, transformative cancer treatments.”

Source: RevenueBase Database · checked Sep 16, 2026
23Indirect evidenceWaltham, MA, United StatesHQ checked Sep 16, 202651-20048 contacts →

Indirect evidence

“Crescent Biopharma’s vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients.”

Source: RevenueBase Database · checked Sep 16, 2026
24Indirect evidenceCambridge, MA, United StatesHQ checked Sep 16, 202611-5047 contacts →

Indirect evidence

“Crossbow Therapeutics, Inc, is a biotechnology company determined to improve the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor…”

Source: RevenueBase Database · checked Sep 16, 2026
25Indirect evidenceFort Lauderdale, FL, United StatesHQ checked Sep 16, 202651-20045 contacts →

Indirect evidence

“LEGION-100 Trial for Metastatic Prostate Cancer is Now Enrolling - Learn More: Syncromune is a privately held, clinical-stage biopharmaceutical company dedicated to the…”

Source: RevenueBase Database · checked Sep 16, 2026

Showing 25 of 169 checkpoint inhibitor manufacturers based in the United States

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Checkpoint inhibitor manufacturers based in the United States at a glance

As of Sep 16, 2026
49.3%Verified-email coverage
30.8Average contacts per company
11-50Median size (employees)
10.7%Largest-city concentration · Cambridge
Sep 16, 2026Page data refreshed

Companies by employee count

1-10
67
11-50
59
51-200
34
201-500
4
501-1,000
3
10001+
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 169 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among checkpoint inhibitor manufacturers, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “checkpoint inhibitor manufacturers”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names checkpoint inhibitor manufacturers), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among checkpoint inhibitor manufacturers, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 2,566 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 16, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names checkpoint inhibitor manufacturers, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many checkpoint inhibitor manufacturers are there based in the United States?

RevenueBase identified 169 checkpoint inhibitor manufacturers headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Dendreon, headquartered in Seal Beach, tops this list with the largest team on record.

Which city has the most checkpoint inhibitor manufacturers?

Cambridge leads with 18 headquartered companies, followed by San Diego (11) and South San Francisco (8).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 2,566 verified decision-maker contacts tracked across these 169 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 16, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.