Company lists · Data refreshed September 2026

Top 25 Cardiac drug developers based in the United States

RevenueBase identified 139 cardiac drug developers headquartered in the United States as of September 2026 and tracks 4,404 professional contacts across them, including 1,676 with verified work emails. San Diego is the largest hub.

This list covers cardiac drug developers headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 19, 2026 86% judged on-target in blind review
139Companies
4,404Contacts tracked
1,676Verified emails
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The 25 largest cardiac drug developers based in the United States

Ranked by team size
Top 25 of 139 cardiac drug developers based in the United States, ranked by team size, largest first. Data refreshed Sep 19, 2026. RevenueBase Smart Search rates how each company's information relates to cardiac drug developers: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceDanbury, CT, United StatesHQ checked Sep 19, 2026501-1,000732 contacts →

Indirect evidence

“MannKind Corporation (Nasdaq: MNKD) is a biopharmaceutical company dedicated to transforming chronic disease care through innovative, patient-centric solutions.”

Source: RevenueBase Database · checked Sep 19, 2026
2Indirect evidencePalo Alto, CA, United StatesHQ checked Sep 19, 2026201-500440 contacts →

Indirect evidence

“CV Therapeutics, Inc.”

Source: RevenueBase Database · checked Sep 19, 2026
3Indirect evidenceLexington, MA, United StatesHQ checked Sep 19, 2026201-500365 contacts →

Indirect evidence

“Kiniksa is a biopharmaceutical company dedicated to improving the lives of patients suffering from debilitating diseases by discovering, acquiring, developing, and commercializing…”

Source: RevenueBase Database · checked Sep 19, 2026
4Partial evidenceBridgewater, NJ, United StatesHQ checked Sep 19, 2026201-500305 contacts →

Partial evidence

“Amarin is a global pharmaceutical company committed to reducing the cardiovascular disease (CVD) burden for patients and communities and to advancing the science of cardiovascular…”

Source: RevenueBase Database · checked Sep 19, 2026
5Partial evidenceHouston, TX, United StatesHQ checked Sep 19, 2026201-500281 contacts →

Partial evidence

“The Texas Heart Institute at Baylor College of Medicine (THI), is a comprehensive cardiovascular health and research center located in the world-renowned Texas Medical Center…”

Source: RevenueBase Database · checked Sep 19, 2026
6Partial evidenceNew York, NY, United StatesHQ checked Sep 19, 202651-200230 contacts →

Partial evidence

“The Cardiovascular Research Foundation® (CRF®) is a global leader in interventional cardiovascular medicine, driving innovation, spearheading groundbreaking research, and…”

Source: RevenueBase Database · checked Sep 19, 2026
7Partial evidenceMinneapolis, MN, United StatesHQ checked Sep 19, 202651-200200 contacts →

Partial evidence

“For over 40 years, the Minneapolis Heart Institute Foundation® (MHIF) has been one of the leading nonprofit cardiovascular and vascular research and education institutions in the…”

Source: RevenueBase Database · checked Sep 19, 2026
8Partial evidenceGermantown, TN, United StatesHQ checked Sep 19, 2026201-500180 contacts →

Partial evidence

“The Stern Cardiovascular Center is recognized as among the largest medical research facilities in the country and provides state-of-the-art diagnostics and treatment of all…”

Source: RevenueBase Database · checked Sep 19, 2026
9Partial evidenceEagan, MN, United StatesHQ checked Sep 19, 202651-200152 contacts →

Partial evidence

“Anteris® Technologies is a global healthcare company dedicated to revolutionizing cardiac care.”

Source: RevenueBase Database · checked Sep 19, 2026
10Partial evidenceBoulder, CO, United StatesHQ checked Sep 19, 202651-200142 contacts →

Partial evidence

“Edgewise Therapeutics, Inc.(Nasdaq: EWTX) is a leading clinical-stage biopharmaceutical company focused on cardiovascular diseases.”

Source: RevenueBase Database · checked Sep 19, 2026
11Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 19, 202651-200119 contacts →

Indirect evidence

“Tenaya Therapeutics is a clinical stage biotechnology company.”

Source: RevenueBase Database · checked Sep 19, 2026
12Partial evidenceBurlington, MA, United StatesHQ checked Sep 19, 202611-5074 contacts →

Partial evidence

“Cardurion Pharmaceuticals is a next generation cardiovascular company focused on the discovery and development of novel therapeutics for the treatment of heart failure and other…”

Source: RevenueBase Database · checked Sep 19, 2026
13Indirect evidencePleasanton, CA, United StatesHQ checked Sep 19, 202651-20071 contacts →

Indirect evidence

“Every moment is a chance to change our future.”

Source: RevenueBase Database · checked Sep 19, 2026
14Indirect evidenceSanta Clara, CA, United StatesHQ checked Sep 19, 202611-5063 contacts →

Indirect evidence

“Ancora Heart is a medical device company dedicated to providing new treatment options for people with heart failure (HF).”

Source: RevenueBase Database · checked Sep 19, 2026
15Partial evidenceSaint Louis, MO, United StatesHQ checked Sep 19, 2026n/a46 contacts →

Partial evidence

“Safebeat Rx (YC S21) makes software that powers cardiac therapeutics monitoring, all from your phone.”

Source: RevenueBase Database · checked Sep 19, 2026
16Indirect evidenceSouthlake, TX, United StatesHQ checked Sep 19, 202611-5043 contacts →

Indirect evidence

“Renibus is a clinical stage biopharmaceutical company dedicated to treating, improving and extending patients’ lives by developing breakthrough products to prevent disease…”

Source: RevenueBase Database · checked Sep 19, 2026
17Partial evidenceMiami, FL, United StatesHQ checked Sep 19, 2026201-50038 contacts →

Partial evidence

“Veru is a late clinical stage biopharmaceutical company focused on developing innovative medicines for the treatment of cardiometabolic and inflammatory diseases.”

Source: RevenueBase Database · checked Sep 19, 2026
18Partial evidenceHouston, TX, United StatesHQ checked Sep 19, 202611-5037 contacts →

Partial evidence

“Procyrion is dedicated to improving outcomes for patients with cardiac and renal impairment using its catheter-deployed pump technology to address conditions with significant…”

Source: RevenueBase Database · checked Sep 19, 2026
19Partial evidenceDurham, NC, United StatesHQ checked Sep 19, 202611-5034 contacts →

Partial evidence

“Myocardial Solutions, Inc.(MSI) is a medical technology company working to transform the cardiac and cancer care continuum.”

Source: RevenueBase Database · checked Sep 19, 2026
20Partial evidenceGaithersburg, MD, United StatesHQ checked Sep 19, 202611-5031 contacts →

Partial evidence

“CVPath Institute is the leading medical research and educational organization dedicated to improving patient health management for those suffering from cardiac and vascular…”

Source: RevenueBase Database · checked Sep 19, 2026
21Partial evidenceSingapore, United StatesHQ checked Sep 19, 202611-5030 contacts →

Partial evidence

“Nuevocor, with offices in USA and Singapore, is developing genetic medicines for untreatable genetic cardiomyopathies by leveraging insights from our PrOSIA mechanobiology…”

Source: RevenueBase Database · checked Sep 19, 2026
22Partial evidenceWilmington, DE, United StatesHQ checked Sep 19, 202611-5026 contacts →

Partial evidence

“We are a clinical-stage pharmaceutical company developing therapeutics to modify the course of cardiopulmonary diseases, namely, Pulmonary Arterial Hypertension (“PAH”), in which…”

Source: RevenueBase Database · checked Sep 19, 2026
23Partial evidenceChapel Hill, United StatesHQ checked Sep 19, 202611-5021 contacts →

Partial evidence

“Tenax Therapeutics is a Phase 3, development-stage pharmaceutical company using clinical insights to develop novel cardiopulmonary therapies.”

Source: RevenueBase Database · checked Sep 19, 2026
24Indirect evidenceRaleigh, NC, United StatesHQ checked Sep 19, 202611-5020 contacts →

Indirect evidence

“NuPulse is focused on the development of innovative treatment options to radically impact treatment and outcomes for patients with chronic heart failure.”

Source: RevenueBase Database · checked Sep 19, 2026
25Partial evidenceCharlottesville, VA, United StatesHQ checked Sep 19, 202611-5016 contacts →

Partial evidence

“Adovate develops novel drugs that target adenosine receptors involved in major diseases.”

Source: RevenueBase Database · checked Sep 19, 2026

Showing 25 of 139 cardiac drug developers based in the United States

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Cardiac drug developers based in the United States at a glance

As of Sep 19, 2026
38.1%Verified-email coverage
31.7Average contacts per company
11-50Median size (employees)
5.8%Largest-city concentration · San Diego
Sep 19, 2026Page data refreshed

Companies by employee count

1-10
63
11-50
51
51-200
14
201-500
9
501-1,000
2

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 139 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among cardiac drug developers, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “cardiac drug developers”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names cardiac drug developers), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among cardiac drug developers, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 1,676 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names cardiac drug developers, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many cardiac drug developers are there based in the United States?

RevenueBase identified 139 cardiac drug developers headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Mannkind Corporation, headquartered in Danbury, tops this list with the largest team on record.

Which city has the most cardiac drug developers?

San Diego leads with 8 headquartered companies, followed by Houston (7) and Boston (6).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,676 verified decision-maker contacts tracked across these 139 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.