Company lists · Data refreshed September 2026

Top 25 Scientific software companies worldwide

RevenueBase identified 536 scientific software companies worldwide as of September 2026 and tracks 16,731 professional contacts across them, including 6,528 with verified work emails. The United States is the largest market and London the largest hub.

This list covers scientific software companies worldwide, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 29, 2026. Country and city lists for scientific software companies follow the table.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 29, 2026 86% judged on-target in blind review
536Companies
16,731Contacts tracked
6,528Verified emails
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The 25 largest scientific software companies worldwide

Ranked by team size
Top 25 of 536 scientific software companies worldwide, ranked by team size, largest first. Data refreshed Sep 29, 2026. RevenueBase Smart Search rates how each company's information relates to scientific software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceNatick, MA, United StatesHQ checked Sep 29, 20265,001-10,0006,694 contacts →

Partial evidence

“MathWorks is the leading developer of mathematical computing software.”

Source: RevenueBase Database · checked Sep 29, 2026
2Partial evidenceCary, NC, United StatesHQ checked Sep 29, 2026201-500557 contacts →

Partial evidence

“Great software in the right hands can change the world.”

Source: RevenueBase Database · checked Sep 29, 2026
3Strong evidenceChampaign, IL, United StatesHQ checked Sep 29, 2026501-1,000551 contacts →

Strong evidence

“Founded by Stephen Wolfram in 1987, Wolfram Research is one of the world's most respected computer, web, and cloud software companies-as well as a powerhouse of scientific and…”

Source: RevenueBase Database · checked Sep 29, 2026
4Partial evidenceBurlington, MA, United StatesHQ checked Sep 29, 2026501-1,000521 contacts →

Partial evidence

“COMSOL develops mathematical modeling software for driving new breakthroughs in physics and engineering.”

Source: RevenueBase Database · checked Sep 29, 2026
5Strong evidenceBoston, MA, United StatesHQ checked Sep 29, 2026501-1,000405 contacts →

Strong evidence

“Dotmatics is the global leader in R&D scientific software that connects science, data, and decision-making.”

Source: RevenueBase Database · checked Sep 29, 2026
6Indirect evidenceFlorianópolis, BrazilHQ checked Sep 29, 2026201-500393 contacts →

Indirect evidence

“Since 1995 has gathered the engineering and computer science knowledge necessary to deliver a complete range of mathematical modeling and numerical simulation solutions to a wide…”

Source: RevenueBase Database · checked Sep 29, 2026
7Indirect evidenceHouston, TX, United StatesHQ checked Sep 29, 2026201-500263 contacts →

Indirect evidence

“New technologies developed by the research and product development teams of Rock Flow Dynamics are integrated into the company’s flagship product – tNavigator.”

Source: RevenueBase Database · checked Sep 29, 2026
8Indirect evidenceMelville, NY, United StatesHQ checked Sep 29, 2026201-500247 contacts →

Indirect evidence

“CD-adapco is a Siemens business focused on CFD engineering simulation with a unique vision for Multidisciplinary Design eXploration (MDX).”

Source: RevenueBase Database · checked Sep 29, 2026
9Indirect evidenceAlicante, SpainHQ checked Sep 29, 2026201-500172 contacts →

Indirect evidence

“CYPE’s journey began in 1983 with an intense activity in the field of engineering and structural analysis, which motivated the computer development of applications to cover its…”

Source: RevenueBase Database · checked Sep 29, 2026
10Partial evidenceOxford, United KingdomHQ checked Sep 29, 202651-200154 contacts →

Partial evidence

“nAG has played a leading role in numerical, scientific and high-performance computing for over 5 decades.”

Source: RevenueBase Database · checked Sep 29, 2026
11Partial evidenceWaterloo, ON, CanadaHQ checked Sep 29, 202651-200132 contacts →

Partial evidence

“Maplesoft has provided mathematics-based software solutions to educators, engineers, and researchers in science, technology, engineering, and mathematics (STEM) for over 35 years.”

Source: RevenueBase Database · checked Sep 29, 2026
12Partial evidenceCollege Station, TX, United StatesHQ checked Sep 29, 202651-200123 contacts →

Partial evidence

“At StataCorp, we are researchers who build powerful, reliable statistical software designed for researchers, analysts, and data professionals.”

Source: RevenueBase Database · checked Sep 29, 2026
13Partial evidenceSanta Fe, NM, United StatesHQ checked Sep 29, 202651-200121 contacts →

Partial evidence

“OpenEye, Cadence Molecular Sciences is an industry leader in computational molecular design based on decades of delivering rapid, robust, and scalable software, toolkits, and…”

Source: RevenueBase Database · checked Sep 29, 2026
14Partial evidenceLondon, United KingdomHQ checked Sep 29, 202651-200112 contacts →

Partial evidence

“H.E.L Group’s mission is to work together with chemistry, safety and biotechnology experts to engineer and unleash the full potential of the scientific community.”

Source: RevenueBase Database · checked Sep 29, 2026
15Indirect evidenceNanterre, FranceHQ checked Sep 29, 202651-20099 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 29, 2026
16Partial evidenceBarcelona, SpainHQ checked Sep 29, 202651-20099 contacts →

Partial evidence

“Wiris is a pioneering software development company founded over 25 years ago and headquartered in Barcelona with offices in Long Beach, California.”

Source: RevenueBase Database · checked Sep 29, 2026
17Partial evidenceRosario, ArgentinaHQ checked Sep 29, 202651-20081 contacts →

Partial evidence

“Somos una empresa dedicada al desarrollo y comercialización de software para profesionales en Ciencias Económicas, para PyMes y emprendimientos, con más de 30 años de liderazgo y…”

Source: RevenueBase Database · checked Sep 29, 2026
18Partial evidenceBogota, ColombiaHQ checked Sep 29, 202651-20080 contacts →

Partial evidence

“Software Shop ® El Distribuidor de Software Científico Líder en Latinoamérica.”

Source: RevenueBase Database · checked Sep 29, 2026
19Strong evidenceParis, FranceHQ checked Sep 29, 202651-20073 contacts →

Strong evidence

“Discngine is a leading developer and provider of scientific software for Life Science Research organizations.”

Source: RevenueBase Database · checked Sep 29, 2026
20Partial evidenceAustin, TX, United StatesHQ checked Sep 29, 202651-20072 contacts →

Partial evidence

“Enthought has been at the forefront of scientific computing for 25 years with a legacy that includes pioneering the open-source scientific Python ecosystem, helping define modern…”

Source: RevenueBase Database · checked Sep 29, 2026
21Partial evidenceSantiago De Compostela, SpainHQ checked Sep 29, 202651-20071 contacts →

Partial evidence

“Mestrelab Research (Mestrelab) is a leading software development company specializing in innovative solutions for analytical chemistry.”

Source: RevenueBase Database · checked Sep 29, 2026
22Indirect evidenceKraków, PolandHQ checked Sep 29, 202651-20065 contacts →

Indirect evidence

“SOLIDEXPERT has been present on the Polish market for over 20 years.”

Source: RevenueBase Database · checked Sep 29, 2026
23Partial evidenceMontreal, QC, CanadaHQ checked Sep 29, 202651-20063 contacts →

Partial evidence

“CCG (Chemical Computing Group) is a leading supplier of software solutions for life sciences.”

Source: RevenueBase Database · checked Sep 29, 2026
24Partial evidenceBoston, MA, United StatesHQ checked Sep 29, 202651-20059 contacts →

Partial evidence

“Protein Metrics' vendor-neutral software allows scientists to use data generated on analytical instruments like mass spectrometers to quickly identify and report protein sequences…”

Source: RevenueBase Database · checked Sep 29, 2026
25Partial evidenceCambridge, United KingdomHQ checked Sep 29, 202651-20053 contacts →

Partial evidence

“Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis.”

Source: RevenueBase Database · checked Sep 29, 2026

Showing 25 of 536 scientific software companies worldwide

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Scientific software companies worldwide at a glance

As of Sep 29, 2026
39.0%Verified-email coverage
31.2Average contacts per company
1-10Median size (employees)
1.9%Largest-city concentration · London
Sep 29, 2026Page data refreshed

Companies by employee count

1-10
330
11-50
141
51-200
39
201-500
12
501-1,000
8
1,001-5,000
2
5,001-10,000
2

Email recency is reported on each country list linked below.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among scientific software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
Coverage
Every country. Country and city lists for scientific software companies are linked below.
What qualifies
Companies worldwide whose own description of what they do matches “scientific software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names scientific software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among scientific software companies, and records with no verified work email.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 6,528 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 29, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Scientific software companies by location

4 lists · largest first

Every Scientific software companies list RevenueBase publishes, by country and city. Counts are matching companies in each list as of its own refresh date.

Countries

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names scientific software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many scientific software companies are there worldwide?

RevenueBase identified 536 scientific software companies worldwide as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Mathworks, headquartered in Natick, tops this list with the largest team on record.

Which country has the most scientific software companies?

The United States leads with 134 companies, followed by the United Kingdom (38) and Germany (35). Every scientific software companies list by country and city is linked on this page.

Which city has the most scientific software companies?

London leads with 10 headquartered companies, followed by Montreal (7) and Cambridge (6).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 6,528 verified decision-maker contacts tracked across these 536 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 29, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.