Company lists · Data refreshed September 2026
Top 25 Directed evolution companies worldwide
RevenueBase identified 501 directed evolution companies worldwide as of September 2026 and tracks 16,587 professional contacts across them, including 4,231 with verified work emails. The United States is the largest market and San Diego the largest hub.
This list covers directed evolution companies worldwide, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026. Country and city lists for directed evolution companies follow the table.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest directed evolution companies worldwide
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 5,582 contacts → | ||||
Indirect evidence “At Novonesis, we believe solutions rooted in biology are key to tackling the challenges our world faces.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 2 | 2,783 contacts → | ||||
Indirect evidence “Novozymes has combined with Chr.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 3 | 1,230 contacts → | ||||
Indirect evidence “Twist Bioscience is a synthetic biology company based in South San Francisco, California.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 4 | 270 contacts → | ||||
Indirect evidence “Codexis is redefining what is possible in therapeutic development and manufacturing, leading the technology revolution with efficient, high-quality, and commercially proven…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 5 | 228 contacts → | ||||
Indirect evidence “Watchmaker Genomics is a biotechnology company that specializes in advanced enzymology to develop precision tools for life sciences.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 6 | 155 contacts → | ||||
Indirect evidence “Born from the founders’ recognition that their diverse but complementary skills and experiences would enable them to successfully address challenges that others had not, Nautilus…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 7 | 143 contacts → | ||||
Indirect evidence “Gencrest started in November 2016.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 8 | 140 contacts → | ||||
Indirect evidence “Vector Laboratories serves and partners with scientists and industry teams developing the next generation of diagnostics, therapeutics, and biological insights.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 9 | 123 contacts → | ||||
Partial evidence “Sail Biomedicines is creating a new class of RNA medicines designed to instruct therapeutic activity directly inside a patient’s body and within selected cells.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 10 | 122 contacts → | ||||
Indirect evidence “ATUM is an industry-leading provider of life science tools and solutions.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 11 | 105 contacts → | ||||
Indirect evidence “Asimov builds tools to program living cells.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 12 | 98 contacts → | ||||
Indirect evidence “Evogene Ltd.(Nasdaq/TASE: EVGN) is a pioneering company in computational chemistry, specializing in the generative design of small molecules for the pharmaceutical and…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 13 | 89 contacts → | ||||
Indirect evidence “Leverage AI to generate protein candidates and improve their properties.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 14 | 87 contacts → | ||||
Indirect evidence “We are now at the dawn of the synthetic biology revolution, which will spawn new applications, markets, and business models, improving human lives in countless ways.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 15 | 87 contacts → | ||||
Indirect evidence “We’re Amano Enzyme (or Amano for short), and our dedication to advancing enzyme technology has been unwavering for generations.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 16 | 85 contacts → | ||||
Indirect evidence “Biocatalysts is a biotechnology company producing speciality enzymes at commercial scales for a variety of industries.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 17 | 79 contacts → | ||||
Indirect evidence “Arzeda, The Protein Design Company™, is a synthetic biology company that creates novel proteins, enzymes and specialty chemical products that compete on performance, cost and…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 18 | 73 contacts → | ||||
Indirect evidence “Our mission is to create a new generation of smarter medicines that outmaneuver complex diseases in ways previously inconceivable.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 19 | 70 contacts → | ||||
Indirect evidence “c-LEcta is a global biotechnology company with over 20 years experience in the development, production and distribution of enzyme products.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 20 | 70 contacts → | ||||
Indirect evidence “Metaphore Biotechnologies is harnessing the power of biomimicry and machine learning to unlock the transformative therapeutic potential of functional molecular mimics.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 21 | 64 contacts → | ||||
Indirect evidence “Infinita Biotech is a leading research oriented Biotech Company which is recognised by the Department of Scientific & Industrial Research, Ministry of Science & Technology…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 22 | 64 contacts → | ||||
Indirect evidence “A Company with the vision of revolutionizing Drug Discovery.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 23 | 61 contacts → | ||||
Indirect evidence “Roal Oy is one of the world´s largest enzyme companies.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 24 | 56 contacts → | ||||
Indirect evidence Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 25 | 55 contacts → | ||||
Partial evidence “Manifold Bio is a platform therapeutics company building the first AI-guided direct-to-vivo discovery platform.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: directed evolution companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names directed evolution companies.
- Partial evidence
- Its own public description names part of directed evolution companies, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name directed evolution companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 501 directed evolution companies worldwide
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Directed evolution companies worldwide at a glance
As of Sep 19, 2026Companies by employee count
Email recency is reported on each country list linked below.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among directed evolution companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- Coverage
- Every country. Country and city lists for directed evolution companies are linked below.
- What qualifies
- Companies worldwide whose own description of what they do matches “directed evolution companies”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names directed evolution companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among directed evolution companies, and records with no verified work email.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 4,231 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Directed evolution companies by location
4 lists · largest firstEvery Directed evolution companies list RevenueBase publishes, by country and city. Counts are matching companies in each list as of its own refresh date.
Countries
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names directed evolution companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many directed evolution companies are there worldwide?
RevenueBase identified 501 directed evolution companies worldwide as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Novonesis, headquartered in Worldwide, tops this list with the largest team on record.
Which country has the most directed evolution companies?
The United States leads with 138 companies, followed by India (32) and the United Kingdom (29). Every directed evolution companies list by country and city is linked on this page.
Which city has the most directed evolution companies?
San Diego leads with 10 headquartered companies, followed by Boston (8) and Cambridge (8).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 4,231 verified decision-maker contacts tracked across these 501 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.