Company lists · Data refreshed November 2026

Top 22 Blockchain interoperability companies based in the United States

RevenueBase identified 50 company matches for blockchain interoperability companies associated with the United States as of November 2026 and tracks 1,018 professional contacts across them, including 310 with verified work emails. San Francisco is the largest hub.

This list covers company matches for blockchain interoperability companies associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed November 6, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Nov 6, 2026 How this list was built
50Companies
1,018Contacts tracked
310Verified emails
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The 22 largest blockchain interoperability companies based in the United States

Ranked by team size
Top 22 of 50 company matches for blockchain interoperability companies based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Nov 6, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchBerkeley, CA, United StatesHQ recorded Nov 6, 202651-200165 contacts →

Exact match

“Supercharging Web3 for a better, decentralized future Web3 needs faster, more secure, more decentralized blockchain infrastructure.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
2Exact matchUnited StatesHQ recorded Nov 6, 202651-200156 contacts →

Exact match

“All chains.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
3Exact matchRemote First, United StatesHQ recorded Nov 6, 202651-200111 contacts →

Exact match

“OP Labs is the team building the technology that powers Optimism, the leading blockchain infrastructure provider enabling developers and enterprises to build the next generation…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
4Exact matchSan Francisco, CA, United StatesHQ recorded Nov 6, 202611-50105 contacts →

Exact match

“Eco is the stablecoin network that makes money programmable across every major blockchain.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
5Exact matchSan Francisco, United StatesHQ recorded Nov 6, 202611-5059 contacts →

Exact match

“ZetaChain is the private memory layer for AI and the infrastructure behind the AI consumer layer.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
6Exact matchSan Francisco, United StatesHQ recorded Nov 6, 202611-5040 contacts →

Exact match

“Analog is a completely decentralized, PoT-based, layer-0 platform for communicating validated event data.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
7Exact matchPalo Alto, CA, United StatesHQ recorded Nov 6, 202611-5036 contacts →

Exact match

“About Enya We create hybrid blockchain solutions that enable the evolution of the borderless economy for businesses and individuals, delivering security, privacy, and scalability.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
8Exact matchSan Francisco And New York City, CA, United StatesHQ recorded Nov 6, 202611-5032 contacts →

Exact match

“Halliday is a blockchain company and product lab working to create a unified, cross-chain payments ecosystem.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
9Exact matchNew York, United StatesHQ recorded Nov 6, 202611-5029 contacts →

Exact match

“Polymer Labs is building the interoperability layer for modular blockchains - enabling secure, seamless communication between rollups and chains.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
10Exact matchSan Francisco, CA, United StatesHQ recorded Nov 6, 202611-5028 contacts →

Exact match

“Agoric is a blockchain product company building seamless, intelligent cross-chain applications-powered by Orchestration.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
11Exact matchBradenton, FL, United StatesHQ recorded Nov 6, 202611-5026 contacts →

Exact match

“Wire Network is the Financial Control Plane for the Autonomous Economy.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
12Exact matchNew York, United StatesHQ recorded Nov 6, 202611-5021 contacts →

Exact match

“Hyperlane is the open interoperability framework.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
13Exact matchSan Diego, CA, United StatesHQ recorded Nov 6, 202611-5018 contacts →

Exact match

“Cross-chain infrastructure for programmable money, tokenized assets, and onchain finance.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
14Exact matchSan Francisco, CA, United StatesHQ recorded Nov 6, 20261-1011 contacts →

Exact match

“Founded in 2024, Able Labs is building the next evolution of DeFi with a permissionless, decentralized protocol across multiple chains.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
15Exact matchMiami, FL, United StatesHQ recorded Nov 6, 202611-5010 contacts →

Exact match

“Keeta Network is a high-performance blockchain network that bridges traditional finance and digital assets.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
16Exact matchSeattle, WA, United StatesHQ recorded Nov 6, 202611-5010 contacts →

Exact match

“At Notifi, we are building the cross-chain communication infrastructure and tooling for all Web3 projects to better manage their users and communities.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
17Exact matchNewark, DE, United StatesHQ recorded Nov 6, 202611-509 contacts →

Exact match

“Your business should not have to spend hundreds of thousands to get started with blockchain technology.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
18Exact matchLong Island City, NY, United StatesHQ recorded Nov 6, 202611-508 contacts →

Exact match

“Skip is a blockchain infrastructure startup.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
19Exact matchNew York, NY, United StatesHQ recorded Nov 6, 202651-2006 contacts →

Exact match

“Symbiont is a leading technology company focused on solving complex global finance problems using a novel enterprise blockchain solution.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
20Exact matchBrooklyn, United StatesHQ recorded Nov 6, 20261-103 contacts →

Exact match

“We are building the first natively omnichain NFT platform and marketplace, Omni X.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
21Exact matchBrooklyn, NY, United StatesHQ recorded Nov 6, 20261-103 contacts →

Exact match

“NFTBridges.xyz is a cutting-edge platform that connects different blockchain networks and enables seamless transfer of NFTs between them.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
22Exact matchNew York, NY, United StatesHQ recorded Nov 6, 202611-501 contacts →

Exact match

“SaaSy Labs provides blockchain native solutions for bringing business on-chain”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase

Showing 22 of 50 blockchain interoperability companies based in the United States

See the full list, filter by size, metro and specialty, and access 310 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Blockchain interoperability companies based in the United States at a glance

As of Nov 6, 2026
30.5%Verified-email coverage
20.4Average contacts per company
11-50Median size (employees)
16.0%Largest-city concentration · San Francisco
Nov 6, 2026Page data refreshed

Companies by employee count

1-10
21
11-50
24
51-200
5

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 50 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “blockchain interoperability companies” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 310 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on November 6, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “blockchain interoperability companies”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many blockchain interoperability companies are there based in the United States?

RevenueBase identified 50 company matches for blockchain interoperability companies associated with the United States as of November 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

SUPRA tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most blockchain interoperability companies?

San Francisco leads with 8 company records, followed by New York (6) and Brooklyn (2).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 310 professional contacts with verified work emails tracked across these 50 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on November 6, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.