Company lists · Data refreshed September 2026

Top 25 Blockchain infrastructure companies based in the United States

RevenueBase identified 625 blockchain infrastructure companies headquartered in the United States as of September 2026 and tracks 8,332 professional contacts across them, including 2,196 with verified work emails. New York is the largest hub.

This list covers blockchain infrastructure companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 19, 2026 86% judged on-target in blind review
625Companies
8,332Contacts tracked
2,196Verified emails
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The 25 largest blockchain infrastructure companies based in the United States

Ranked by team size
Top 25 of 625 blockchain infrastructure companies based in the United States, ranked by team size, largest first. Data refreshed Sep 19, 2026. RevenueBase Smart Search rates how each company's information relates to blockchain infrastructure companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 2026501-1,0001,275 contacts →

Partial evidence

“Using proven crypto and blockchain technology honed over a decade, Ripple’s enterprise-grade solutions are faster, more transparent, and more cost-effective than traditional…”

Source: RevenueBase Database · checked Sep 19, 2026
2Strong evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 202651-200329 contacts →

Strong evidence

“Alchemy powers the blockchain infrastructure to accelerate the world's leading financial applications.”

Source: RevenueBase Database · checked Sep 19, 2026
3Partial evidenceChicago, IL, United StatesHQ checked Sep 19, 202651-200217 contacts →

Partial evidence

“zerohash is the leading infrastructure provider for crypto, stablecoin, and tokenized assets.”

Source: RevenueBase Database · checked Sep 19, 2026
4Partial evidenceNew York, NY, United StatesHQ checked Sep 19, 2026n/a204 contacts →

Partial evidence

“Avalanche is a high-performance blockchain platform built for business.”

Source: RevenueBase Database · checked Sep 19, 2026
5Partial evidenceRemote First, United StatesHQ checked Sep 19, 2026201-500202 contacts →

Partial evidence

“Blockdaemon is the infrastructure powering the digital asset economy.”

Source: RevenueBase Database · checked Sep 19, 2026
6Strong evidenceBerkeley, CA, United StatesHQ checked Sep 19, 202651-200178 contacts →

Strong evidence

“Supercharging Web3 for a better, decentralized future Web3 needs faster, more secure, more decentralized blockchain infrastructure.”

Source: RevenueBase Database · checked Sep 19, 2026
7Indirect evidenceUnited StatesHQ checked Sep 19, 202651-200161 contacts →

Indirect evidence

“All chains.”

Source: RevenueBase Database · checked Sep 19, 2026
8Partial evidenceNew York, NJ, United StatesHQ checked Sep 19, 202651-200141 contacts →

Partial evidence

“Offchain is the strategic infrastructure partner for the world’s most ambitious companies.”

Source: RevenueBase Database · checked Sep 19, 2026
9Partial evidenceRochester, NY, United StatesHQ checked Sep 19, 202651-200124 contacts →

Partial evidence

“As a decentralized infrastructure company, we leverage our expertise, market intelligence, capital gateways, and industry relationships to empower institutional bitcoin miners…”

Source: RevenueBase Database · checked Sep 19, 2026
10Partial evidenceNew York, NY, United StatesHQ checked Sep 19, 202651-200123 contacts →

Partial evidence

“Algorand is the blockchain that scales with your ambition.”

Source: RevenueBase Database · checked Sep 19, 2026
11Strong evidenceIrvine, CA, United StatesHQ checked Sep 19, 202651-200120 contacts →

Strong evidence

“Zeeve is an ISO 27001, SOC2 Type II, and GDPR-compliant Blockchain-Infrastructure-as-a-Service and a Rollups-as-a-Service (RaaS) platform, operating across India, the US, Europe…”

Source: RevenueBase Database · checked Sep 19, 2026
12Partial evidenceNew York, United StatesHQ checked Sep 19, 202611-50119 contacts →

Partial evidence

“Rarible offers the leading infrastructure for onchain marketplaces and collectible experiences with ~500 million dollars in GMV.”

Source: RevenueBase Database · checked Sep 19, 2026
13Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 202611-50117 contacts →

Partial evidence

“Traditional blockchains were designed for human users.”

Source: RevenueBase Database · checked Sep 19, 2026
14Indirect evidenceSeattle, WA, United StatesHQ checked Sep 19, 202651-200108 contacts →

Indirect evidence

“Eigen Labs is an AI research lab building tools for human and agent coordination that preserve and maximize individual agency in the PostAGI era.”

Source: RevenueBase Database · checked Sep 19, 2026
15Partial evidenceMiami, United StatesHQ checked Sep 19, 202651-200105 contacts →

Partial evidence

“Quicknode simplifies blockchain for teams big and small.”

Source: RevenueBase Database · checked Sep 19, 2026
16Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 202651-200103 contacts →

Partial evidence

“Tenderly creates a complete digital twin of any blockchain network so institutions, dev teams, asset managers, and risk managers can model every onchain move against a live system…”

Source: RevenueBase Database · checked Sep 19, 2026
17Partial evidencePalo Alto, CA, United StatesHQ checked Sep 19, 2026201-500103 contacts →

Partial evidence

“HashCash is a blockchain software products company offering trading, payments and other technology products.”

Source: RevenueBase Database · checked Sep 19, 2026
18Strong evidenceRemote First, United StatesHQ checked Sep 19, 202651-20089 contacts →

Strong evidence

“OP Labs is the team building the technology that powers Optimism, the leading blockchain infrastructure provider enabling developers and enterprises to build the next generation…”

Source: RevenueBase Database · checked Sep 19, 2026
19Partial evidenceCarlsbad, CA, United StatesHQ checked Sep 19, 202651-20074 contacts →

Partial evidence

“World Leading Blockchain Products & Services Provider.”

Source: RevenueBase Database · checked Sep 19, 2026
20Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 202611-5070 contacts →

Partial evidence

“ZetaChain is the private memory layer for AI and the infrastructure behind the AI consumer layer.”

Source: RevenueBase Database · checked Sep 19, 2026
21Partial evidenceHouston, TX, United StatesHQ checked Sep 19, 202651-20069 contacts →

Partial evidence

“Qecosystem provides a Global Payments Network, ID Verification, Bespoke Blockchain Data Management services which combine to an Integrated ecosystem where data and value flow…”

Source: RevenueBase Database · checked Sep 19, 2026
22Partial evidenceNew York, NY, United StatesHQ checked Sep 19, 202651-20065 contacts →

Partial evidence

“Turnkey is secure, scalable crypto wallet infrastructure for payments, stablecoins, DeFi and AI agents.”

Source: RevenueBase Database · checked Sep 19, 2026
23Partial evidenceAustin, United StatesHQ checked Sep 19, 202651-20064 contacts →

Partial evidence

“Horizen Labs was founded in 2019 to secure the world’s transition to web3 by building enterprise-grade blockchains and web3 products for the real-world.”

Source: RevenueBase Database · checked Sep 19, 2026
24Indirect evidenceNew York, NY, United StatesHQ checked Sep 19, 202651-20062 contacts →

Indirect evidence

“Founded in 2017, Tassat Group, Inc.”

Source: RevenueBase Database · checked Sep 19, 2026
25Indirect evidenceNew York, NY, United StatesHQ checked Sep 19, 202651-20062 contacts →

Indirect evidence

“Category Labs (formerly known as Monad Labs) is a team of systems engineers and researchers on a mission to design and build at the frontier of decentralized technology.”

Source: RevenueBase Database · checked Sep 19, 2026

Showing 25 of 625 blockchain infrastructure companies based in the United States

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Blockchain infrastructure companies based in the United States at a glance

As of Sep 19, 2026
26.4%Verified-email coverage
13.3Average contacts per company
11-50Median size (employees)
9.4%Largest-city concentration · New York
Sep 19, 2026Page data refreshed

Companies by employee count

1-10
307
11-50
245
51-200
54
201-500
10
501-1,000
5
1,001-5,000
1
10001+
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 625 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among blockchain infrastructure companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “blockchain infrastructure companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names blockchain infrastructure companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among blockchain infrastructure companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 2,196 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Blockchain infrastructure companies by metro

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names blockchain infrastructure companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many blockchain infrastructure companies are there based in the United States?

RevenueBase identified 625 blockchain infrastructure companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Ripple, headquartered in San Francisco, tops this list with the largest team on record.

Which city has the most blockchain infrastructure companies?

New York leads with 59 headquartered companies, followed by San Francisco (53) and Miami (27).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 2,196 verified decision-maker contacts tracked across these 625 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.