Company lists · Data refreshed September 2026
Top 25 Blockchain companies based in San Francisco, United States
RevenueBase identified 132 blockchain companies headquartered in San Francisco, United States as of September 2026 and tracks 3,459 professional contacts across them, including 791 with verified work emails. New York is the largest hub.
This list covers blockchain companies headquartered in San Francisco, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 7, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest blockchain companies based in San Francisco, United States
Ranked by team size| # | Company | RevenueBase Smart Search | Contacts | ||
|---|---|---|---|---|---|
| 1 | Strong evidence | 1,275 contacts → | |||
“Using proven crypto and blockchain technology honed over a decade, Ripple’s enterprise-grade solutions are faster, more transparent, and more cost-effective than traditional…” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 2 | Indirect evidence | 345 contacts → | |||
“TRM Labs is an AI investigations company that helps keep people, institutions, and communities safe from crime.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 3 | Strong evidence | 329 contacts → | |||
“Alchemy powers the blockchain infrastructure to accelerate the world's leading financial applications.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 4 | Strong evidence | 117 contacts → | |||
“Traditional blockchains were designed for human users.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 5 | Strong evidence | 108 contacts → | |||
“Polychain invests in protocols and companies in the blockchain space, advancing the global adoption of cryptocurrencies.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 6 | Strong evidence | 94 contacts → | |||
“Blockchain Capital was founded in 2013 with the mission of helping entrepreneurs build world-class companies and projects based on blockchain technology – providing founders with…” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 7 | Indirect evidence | 70 contacts → | |||
“ZetaChain is the private memory layer for AI and the infrastructure behind the AI consumer layer.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 8 | Strong evidence | 67 contacts → | |||
“Quantstamp is a global leader in blockchain security, on a mission to secure the future of web3.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 9 | Indirect evidence | 67 contacts → | |||
“We are now known as The DATA Foundation.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 10 | Strong evidence | 53 contacts → | |||
“Created by Bram Cohen, the inventor of BitTorrent, the underlying open source, public Chia blockchain provides the secure and regulatory-compliant infrastructure for One Market.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 11 | Indirect evidence | 40 contacts → | |||
“Onboard users with wallets, build & deploy smart contracts, accept fiat with payments, and scale apps with infrastructure, on any EVM chain.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 12 | Indirect evidence | 36 contacts → | |||
“Framework Ventures is a leading VC firm with a track record of partnering with winning founders.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 13 | Indirect evidence | 36 contacts → | |||
“Welcome to N3TWORK Studios!” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 14 | Strong evidence | 35 contacts → | |||
“Loyyal is at the forefront of loyalty and payments innovation, offering a cutting-edge Enterprise SaaS Suite powered by patented blockchain technology.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 15 | Strong evidence | 34 contacts → | |||
“Constellation is the world’s only Blockchain technology designed for Big Data, providing infrastructure for an open decentralized data marketplace and an enterprise-grade software…” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 16 | Strong evidence | 30 contacts → | |||
“Agoric is a blockchain product company building seamless, intelligent cross-chain applications-powered by Orchestration.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 17 | Indirect evidence | 23 contacts → | |||
“Eclipse is a verifiable computing company based in San Francisco, founded in 2022.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 18 | Indirect evidence | 20 contacts → | |||
“At LBank Labs, we thrive on the power of connections and believe in fostering strong relationships within the industry.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 19 | Strong evidence | 18 contacts → | |||
“Ambisafe is a globally recognized blockchain-based software provider.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 20 | Strong evidence | 15 contacts → | |||
“We're building InfiniSVM, a high-performance, hardware-accelerated SVM blockchain engineered for unparalleled scalability and throughput.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 21 | Indirect evidence | 13 contacts → | |||
“At PeopleBrowsr, we are on a mission to change the way influencers, creators and brands connect with their customers/fans.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 22 | Strong evidence | 11 contacts → | |||
“Momentum 6 is a venture capital, venture builder, research, and marketing firm creating the leading blockchain companies of the future.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 23 | Indirect evidence | 10 contacts → | |||
“gCC is a boutique early-stage venture capital firm based in Silicon Valley.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 24 | Indirect evidence | 9 contacts → | |||
“Newzchain is the founder-operated startup intelligence platform for India and the India–Gulf corridor.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
| 25 | Indirect evidence | 9 contacts → | |||
“Founded in 2024, Able Labs is building the next evolution of DeFi with a permissionless, decentralized protocol across multiple chains.” Source: company website · checked Sep 7, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: blockchain companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names blockchain companies.
- Partial evidence
- Its own public description names part of blockchain companies, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name blockchain companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 132 blockchain companies based in San Francisco, United States
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Blockchain companies based in San Francisco, United States at a glance
As of Sep 7, 2026Companies by employee count
Email recency for this list is measured across the whole United States list rather than this city, so it is reported there. Company counts and contact totals on this page are exact for San Francisco, over 132 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among blockchain companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in San Francisco, United States whose own description of what they do matches “blockchain companies”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names blockchain companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among blockchain companies, and records with no verified work email. Companies headquartered outside San Francisco are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 791 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 7, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Blockchain companies by metro in the United States
- Blockchain companies in New York179
- Blockchain companies in San Francisco132
- Blockchain companies in Miami86
- Blockchain companies in Los Angeles73
- Blockchain companies in Austin58
- Blockchain companies in Houston35
- Blockchain companies in Sheridan33
- Blockchain companies in Chicago32
- Blockchain companies in Atlanta28
- Blockchain companies in Dallas26
- Blockchain companies in Denver25
- Blockchain companies in Las Vegas25
- Blockchain companies in Seattle25
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names blockchain companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many blockchain companies are there based in San Francisco, United States?
RevenueBase identified 132 blockchain companies headquartered in San Francisco, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Ripple, headquartered in San Francisco, tops this list with the largest team on record.
Which city has the most blockchain companies?
New York leads with 179 headquartered companies, followed by San Francisco (132) and Miami (86).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 791 verified decision-maker contacts tracked across these 132 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 7, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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