Company lists · Data refreshed September 2026
Top 25 Biotechnology venture capital firms based in Chicago, United States
RevenueBase identified 55 biotechnology venture capital firms headquartered in Chicago, United States as of September 2026 and tracks 624 professional contacts across them, including 291 with verified work emails. New York is the largest hub.
This list covers biotechnology venture capital firms headquartered in Chicago, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 21, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest biotechnology venture capital firms based in Chicago, United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 67 contacts → | ||||
Partial evidence “Portal Innovations is a premier venture development engine that bridges scientific ideation in life sciences, medtech, and bioinformatics through commercial proof of concept by…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 2 | 64 contacts → | ||||
Indirect evidence “At Water Street, we are dedicated to building market leaders in healthcare.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 3 | 62 contacts → | ||||
Partial evidence “Early stage venture firm focused on life science discoveries to prevent, detect and cure disease.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 4 | 59 contacts → | ||||
Indirect evidence “For over 40 years, First Analysis has been at the forefront of supporting emerging growth companies and established leaders across high-growth, technology-driven sectors.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 5 | 56 contacts → | ||||
Indirect evidence “HPA is a leading early-stage investor.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 6 | 40 contacts → | ||||
Indirect evidence “Cressey & Company is a private investment firm focused exclusively on investing and building leading businesses in the healthcare services and healthcare information technology…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 7 | 31 contacts → | ||||
Partial evidence “Abundant Venture Partners was founded on the belief that healthcare’s most important challenges are too complex for any organization to solve alone.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 8 | 28 contacts → | ||||
Indirect evidence “Valtruis invests in, builds, and partners with companies that challenge the healthcare industry’s status quo and revolutionize the way care is accessed, delivered, experienced…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 9 | 23 contacts → | ||||
Strong evidence “2Flo Ventures is a startup studio and venture capital firm dedicated to accelerating impactful innovation in healthcare.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 10 | 16 contacts → | ||||
Partial evidence “7wire Ventures is an early stage, healthcare venture fund.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 11 | 13 contacts → | ||||
Indirect evidence “Thurston Group is a strategic investor and dedicated partner focused exclusively on the healthcare industry.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 12 | 12 contacts → | ||||
Partial evidence “DuneGlass Capital is a growth-oriented investment firm that partners with healthcare founders.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 13 | 10 contacts → | ||||
Indirect evidence “With an in-depth focus on research and exceptional due diligence plus a 30-year track record, VCapital Management Co.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 14 | 10 contacts → | ||||
Strong evidence “OMX Ventures is a venture capital firm focused on investing in a new era of bioengineering and its application for better tools, medicines, foods, industrial products, and more.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 15 | 9 contacts → | ||||
Indirect evidence “We seed and grow companies that will revolutionize business by delivering the promise of AI to the enterprise.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 16 | 8 contacts → | ||||
Partial evidence “Distributed Ventures backs bold founders innovating at the frontier of risk.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 17 | 8 contacts → | ||||
Indirect evidence “Sandalphon leads, co-leads or meaningfully participates in Pre-Seed and Seed stage rounds for B2B healthtech startups Primary industries of interest: HealthTech Tech-Enabled…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 18 | 7 contacts → | ||||
Strong evidence “PACE Healthcare Capital is an early-stage venture firm investing between the coasts to accelerate digital health and healthcare technology companies that improve outcomes, expand…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 19 | 6 contacts → | ||||
Strong evidence “Propellant Ventures is Seed stage venture capital fund that invests in the growth of Chicago and the greater Midwest across a broad range of powerful, diverse, and leading-edge…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 20 | 4 contacts → | ||||
Partial evidence “Ranch Ventures Fund I LLC is an investment banking company based out of 1050 STATE ST, Chicago, Illinois, United States.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 21 | 3 contacts → | ||||
Indirect evidence “Pathway Bioventures is an early-stage life sciences fund for next-generation therapeutics, medical device, and diagnostics companies.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 22 | 2 contacts → | ||||
Strong evidence “Founded in 2013, Kleinmuntz Associates is a closely-held venture capital firm based in Chicago.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 23 | 2 contacts → | ||||
Partial evidence “Venture services firm specializing in the acceleration of market adoption for healthcare startups.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 24 | 2 contacts → | ||||
Strong evidence “Genius Guild, a Chicago-based venture capital firm building a new kind of venture platform focused on creating a world where everyone gets alpha-Investors, Founders, and…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 25 | 2 contacts → | ||||
Strong evidence “Cultivian Sandbox is a venture capital firm focused on building next-generation food and agriculture technology companies capable of generating superior returns.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: biotechnology venture capital firms. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names biotechnology venture capital firms.
- Partial evidence
- Its own public description names part of biotechnology venture capital firms, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name biotechnology venture capital firms. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 55 biotechnology venture capital firms based in Chicago, United States
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Biotechnology venture capital firms based in Chicago, United States at a glance
As of Sep 21, 2026Companies by employee count
Email recency for this list is measured across the whole United States list rather than for Chicago, so it is reported there. Company counts and contact totals on this page are exact for Chicago, over 55 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among biotechnology venture capital firms, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in Chicago, United States whose own description of what they do matches “biotechnology venture capital firms”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names biotechnology venture capital firms), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among biotechnology venture capital firms, and records with no verified work email. Companies headquartered outside Chicago are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 291 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 21, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Biotechnology venture capital firms by metro in the United States
- Biotechnology venture capital firms in New York147
- Biotechnology venture capital firms in San Francisco100
- Biotechnology venture capital firms in Boston88
- Biotechnology venture capital firms in Chicago55
- Biotechnology venture capital firms in Cambridge38
- Biotechnology venture capital firms in Palo Alto37
- Biotechnology venture capital firms in Menlo Park36
- Biotechnology venture capital firms in Austin26
- Biotechnology venture capital firms in San Diego26
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names biotechnology venture capital firms, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many biotechnology venture capital firms are there based in Chicago, United States?
RevenueBase identified 55 biotechnology venture capital firms headquartered in Chicago, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Portal Innovations, headquartered in Chicago, tops this list with the largest team on record.
Which city has the most biotechnology venture capital firms?
New York leads with 147 headquartered companies, followed by San Francisco (100) and Boston (88).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 291 verified decision-maker contacts tracked across these 55 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 21, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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