Company lists · Data refreshed September 2026

Top 20 Biotech venture capital firms based in Chicago, United States

RevenueBase identified 38 biotech venture capital firms headquartered in Chicago, United States as of September 2026 and tracks 394 professional contacts across them, including 187 with verified work emails. New York is the largest hub.

This list covers biotech venture capital firms headquartered in Chicago, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 14, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 14, 2026 86% judged on-target in blind review
38Companies
394Contacts tracked
187Verified emails
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The 20 largest biotech venture capital firms based in Chicago, United States

Ranked by team size
Top 20 of 38 biotech venture capital firms based in Chicago, United States, ranked by team size, largest first. Data refreshed Sep 14, 2026. RevenueBase Smart Search rates how each company's information relates to biotech venture capital firms: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-5067 contacts →

Partial evidence

“Portal Innovations is a premier venture development engine that bridges scientific ideation in life sciences, medtech, and bioinformatics through commercial proof of concept by…”

Source: RevenueBase Database · checked Sep 14, 2026
2Partial evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-5062 contacts →

Partial evidence

“Early stage venture firm focused on life science discoveries to prevent, detect and cure disease.”

Source: RevenueBase Database · checked Sep 14, 2026
3Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-5059 contacts →

Indirect evidence

“For over 40 years, First Analysis has been at the forefront of supporting emerging growth companies and established leaders across high-growth, technology-driven sectors.”

Source: RevenueBase Database · checked Sep 14, 2026
4Partial evidenceChicago, IL, United StatesHQ checked Sep 14, 2026201-50031 contacts →

Partial evidence

“Abundant Venture Partners was founded on the belief that healthcare’s most important challenges are too complex for any organization to solve alone.”

Source: RevenueBase Database · checked Sep 14, 2026
5Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-5025 contacts →

Indirect evidence

“Paragon is a global life science leader that creates, builds and funds innovative biology-based companies, accelerating scientific breakthroughs to solve some of society's most…”

Source: RevenueBase Database · checked Sep 14, 2026
6Strong evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-1023 contacts →

Strong evidence

“2Flo Ventures is a startup studio and venture capital firm dedicated to accelerating impactful innovation in healthcare.”

Source: RevenueBase Database · checked Sep 14, 2026
7Strong evidenceChicago, United StatesHQ checked Sep 14, 20261-1016 contacts →

Strong evidence

“Born out of a love for building startups and a passion for backing entrepreneurs with heart, Corazon Capital (Spanish for “heart”), a leading Chicago-based venture fund, brings a…”

Source: RevenueBase Database · checked Sep 14, 2026
8Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-1010 contacts →

Indirect evidence

“With an in-depth focus on research and exceptional due diligence plus a 30-year track record, VCapital Management Co.”

Source: RevenueBase Database · checked Sep 14, 2026
9Strong evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-1010 contacts →

Strong evidence

“OMX Ventures is a venture capital firm focused on investing in a new era of bioengineering and its application for better tools, medicines, foods, industrial products, and more.”

Source: RevenueBase Database · checked Sep 14, 2026
10Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-109 contacts →

Indirect evidence

“We seed and grow companies that will revolutionize business by delivering the promise of AI to the enterprise.”

Source: RevenueBase Database · checked Sep 14, 2026
11Partial evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-108 contacts →

Partial evidence

“Distributed Ventures backs bold founders innovating at the frontier of risk.”

Source: RevenueBase Database · checked Sep 14, 2026
12Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-107 contacts →

Indirect evidence

“New Stack was founded in 2015 with a mission to invest in the Outsiders.”

Source: RevenueBase Database · checked Sep 14, 2026
13Strong evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-107 contacts →

Strong evidence

“PACE Healthcare Capital is an early-stage venture firm investing between the coasts to accelerate digital health and healthcare technology companies that improve outcomes, expand…”

Source: RevenueBase Database · checked Sep 14, 2026
14Partial evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-104 contacts →

Partial evidence

“Ranch Ventures Fund I LLC is an investment banking company based out of 1050 STATE ST, Chicago, Illinois, United States.”

Source: RevenueBase Database · checked Sep 14, 2026
15Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-103 contacts →

Indirect evidence

“Pathway Bioventures is an early-stage life sciences fund for next-generation therapeutics, medical device, and diagnostics companies.”

Source: RevenueBase Database · checked Sep 14, 2026
16Partial evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-103 contacts →

Partial evidence

“Seyen Capital is a Chicago based VC fund.”

Source: RevenueBase Database · checked Sep 14, 2026
17Partial evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-102 contacts →

Partial evidence

Venture services firm specializing in the acceleration of market adoption for healthcare startups.”

Source: RevenueBase Database · checked Sep 14, 2026
18Strong evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-102 contacts →

Strong evidence

“Founded in 2013, Kleinmuntz Associates is a closely-held venture capital firm based in Chicago.”

Source: RevenueBase Database · checked Sep 14, 2026
19Partial evidenceChicago, United StatesHQ checked Sep 14, 20261-102 contacts →

Partial evidence

“The motivation for Purvi Capital took shape as the great blizzard of 2011 poured sleet and snow at rates exceeding 4 inches/hour over Chicago streets.”

Source: RevenueBase Database · checked Sep 14, 2026
20Partial evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-101 contacts →

Partial evidence

“Aktion Partners is an Information Technology focused investment vehicle that provides capital, strategic oversight and administration services to target entities.”

Source: RevenueBase Database · checked Sep 14, 2026

Showing 20 of 38 biotech venture capital firms based in Chicago, United States

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Biotech venture capital firms based in Chicago, United States at a glance

As of Sep 14, 2026
47.5%Verified-email coverage
10.4Average contacts per company
1-10Median size (employees)
431.6%Largest-city concentration · New York
Sep 14, 2026Page data refreshed

Companies by employee count

1-10
27
11-50
10
201-500
1

Email recency for this list is measured across the whole United States list rather than for Chicago, so it is reported there. Company counts and contact totals on this page are exact for Chicago, over 38 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among biotech venture capital firms, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in Chicago, United States whose own description of what they do matches “biotech venture capital firms”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names biotech venture capital firms), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among biotech venture capital firms, and records with no verified work email. Companies headquartered outside Chicago are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 187 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 14, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names biotech venture capital firms, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many biotech venture capital firms are there based in Chicago, United States?

RevenueBase identified 38 biotech venture capital firms headquartered in Chicago, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Portal Innovations, headquartered in Chicago, tops this list with the largest team on record.

Which city has the most biotech venture capital firms?

New York leads with 164 headquartered companies, followed by San Francisco (164) and Boston (81).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 187 verified decision-maker contacts tracked across these 38 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 14, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.