Company lists · Data refreshed September 2026

Top 25 Biotech software companies based in the United States

Name: Biotech software companies based in the United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 14, 2026 805 companies tracked

RevenueBase identified 805 biotech software companies headquartered in the United States as of September 2026 and tracks 18,360 professional contacts across them, including 7,567 with verified work emails. San Francisco is the largest hub.

This list covers biotech software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 14, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 14, 2026 86% judged on-target in blind review

805Companies

18,360Contacts tracked

7,567Verified emails

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The 25 largest biotech software companies based in the United States

Ranked by team size

Top 25 of 805 biotech software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 14, 2026. RevenueBase Smart Search rates how each company's information relates to biotech software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#	Company	RevenueBase Smart Search	Headquarters	Employees	Contacts
1	Caris Life Sciences	Indirect evidence	Irving, TX, United StatesHQ checked Sep 14, 2026	1,001-5,000	1,556 contacts →
	Indirect evidence “Caris Life Sciences® (Caris) is the leading next-generation TechBio company and precision medicine pioneer that is actively developing and delivering innovative solutions to…” Source: RevenueBase Database · checked Sep 14, 2026
2	Certara	Partial evidence	Radnor, PA, United StatesHQ checked Sep 14, 2026	1,001-5,000	1,237 contacts →
	Partial evidence “Certara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development.” Source: RevenueBase Database · checked Sep 14, 2026
3	Aldevron	Indirect evidence	Fargo, ND, United StatesHQ checked Sep 14, 2026	1,001-5,000	802 contacts →
	Indirect evidence “Aldevron is proud to be part of Danaher.” Source: RevenueBase Database · checked Sep 14, 2026
4	Recursion	Indirect evidence	Salt Lake City, UT, United StatesHQ checked Sep 14, 2026	501-1,000	793 contacts →
	Indirect evidence “Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives.” Source: RevenueBase Database · checked Sep 14, 2026
5	Formulatrix	Partial evidence	Bedford, MA, United StatesHQ checked Sep 14, 2026	1,001-5,000	485 contacts →
	Partial evidence “FORMULATRIX® supplies innovative software and robotic automation solutions to the life science industry including the leading pharmaceutical companies and academic research…” Source: RevenueBase Database · checked Sep 14, 2026
6	Instem	Indirect evidence	Boston, MA, United StatesHQ checked Sep 14, 2026	201-500	450 contacts →
	Indirect evidence “SaaS Products & Services for R&D that drive discovery, accelerate studies, and advance your research.” Source: RevenueBase Database · checked Sep 14, 2026
7	Dotmatics	Partial evidence	Boston, MA, United StatesHQ checked Sep 14, 2026	501-1,000	405 contacts →
	Partial evidence “Dotmatics is the global leader in R&D scientific software that connects science, data, and decision-making.” Source: RevenueBase Database · checked Sep 14, 2026
8	Velsera	Indirect evidence	Charlestown, MA, United StatesHQ checked Sep 14, 2026	501-1,000	369 contacts →
	Indirect evidence “Velsera was formed in 2023 through the shared vision of Seven Bridges and Pierian, with a mission to accelerate the discovery, development, and delivery of life-changing insights.” Source: RevenueBase Database · checked Sep 14, 2026
9	I2e Consulting	Indirect evidence	Groton, CT, United StatesHQ checked Sep 14, 2026	51-200	314 contacts →
	Indirect evidence “i2e drives enterprise transformation for the life sciences industry through AI-powered portfolio and clinical intelligence solutions that power critical decision-making across…” Source: RevenueBase Database · checked Sep 14, 2026
10	Highres	Partial evidence	Beverly, MA, United StatesHQ checked Sep 14, 2026	201-500	276 contacts →
	Partial evidence “HighRes is the leading global lab automation company, empowering scientists to create results by connecting instrumentation, software and data from anywhere in the world.” Source: RevenueBase Database · checked Sep 14, 2026
11	Watchmaker Genomics	Partial evidence	Boulder, CO, United StatesHQ checked Sep 14, 2026	51-200	228 contacts →
	Partial evidence “Watchmaker Genomics is a biotechnology company that specializes in advanced enzymology to develop precision tools for life sciences.” Source: RevenueBase Database · checked Sep 14, 2026
12	Unchained Labs	Indirect evidence	Pleasanton, CA, United StatesHQ checked Sep 14, 2026	201-500	219 contacts →
	Indirect evidence “Here's the deal.” Source: RevenueBase Database · checked Sep 14, 2026
13	Rapid Micro Biosystems	Indirect evidence	Lexington, MA, United StatesHQ checked Sep 14, 2026	51-200	207 contacts →
	Indirect evidence “Rapid Micro Biosystems is a life sciences technology company providing automation solutions that improve the manufacturing process and enable the fast, safe release of critical…” Source: RevenueBase Database · checked Sep 14, 2026
14	Pointcross Life Sciences	Partial evidence	Foster City, CA, United StatesHQ checked Sep 14, 2026	51-200	194 contacts →
	Partial evidence “PointCross Inc, founded in 2007 out of Foster City, CA, is a software company built to provide the life science industry solutions in big data analytics, management, and…” Source: RevenueBase Database · checked Sep 14, 2026
15	Xybion Digital	Indirect evidence	Princeton, NJ, United StatesHQ checked Sep 14, 2026	201-500	191 contacts →
	Indirect evidence “Xybion, now part of Instem, is a leading SaaS provider dedicated to supporting R&D for life sciences and health systems.” Source: RevenueBase Database · checked Sep 14, 2026
16	Automated Engineering Services, INC	Partial evidence	Vista, CA, United StatesHQ checked Sep 14, 2026	201-500	171 contacts →
	Partial evidence “AES (Automated Engineering Services) is a full end-to-end partner for biotech and biopharma manufacturing.” Source: RevenueBase Database · checked Sep 14, 2026
17	Sycamore Informatics INC	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 14, 2026	201-500	169 contacts →
	Indirect evidence “Sycamore Informatics provides the life science industry's premier Enterprise Data Science Application Suite.” Source: RevenueBase Database · checked Sep 14, 2026
18	Circulants	Indirect evidence	Moorpark, CA, United StatesHQ checked Sep 14, 2026	51-200	158 contacts →
	Indirect evidence “Circulants is a rapidly growing IT solutions company based out of Moorpark, California.” Source: RevenueBase Database · checked Sep 14, 2026
19	Nautilus Biotechnology	Indirect evidence	San Carlos, WA, United StatesHQ checked Sep 14, 2026	51-200	155 contacts →
	Indirect evidence “Born from the founders’ recognition that their diverse but complementary skills and experiences would enable them to successfully address challenges that others had not, Nautilus…” Source: RevenueBase Database · checked Sep 14, 2026
20	Digital Infuzion	Partial evidence	Rockville, MD, United StatesHQ checked Sep 14, 2026	51-200	145 contacts →
	Partial evidence “Digital Infuzion is a software and health care IT company.” Source: RevenueBase Database · checked Sep 14, 2026
21	L7 Informatics	Indirect evidence	Austin, TX, United StatesHQ checked Sep 14, 2026	51-200	139 contacts →
	Indirect evidence “L7 Informatics provides a unified data and process platform (L7\|ESP®) to streamline and optimize manufacturing, laboratory, and business processes across life sciences and…” Source: RevenueBase Database · checked Sep 14, 2026
22	Invita Healthcare Technologies	Partial evidence	Baltimore, MD, United StatesHQ checked Sep 14, 2026	51-200	133 contacts →
	Partial evidence “InVita develops specialized software for regulated industries supporting the advancement of public health and safety.” Source: RevenueBase Database · checked Sep 14, 2026
23	Qpharma, INC	Partial evidence	Morristown, NJ, United StatesHQ checked Sep 14, 2026	201-500	133 contacts →
	Partial evidence “Founded in 1994, QPharma is the industry leader in cloud-based software and services for life sciences.” Source: RevenueBase Database · checked Sep 14, 2026
24	Essex, Part Of Emmes Group	Indirect evidence	Rockville, MD, United StatesHQ checked Sep 14, 2026	51-200	127 contacts →
	Indirect evidence “Essex Management is a member of the Emmes Group, a Veridix AI company supporting life sciences technology, staffed with experienced professionals committed to maximizing client…” Source: RevenueBase Database · checked Sep 14, 2026
25	Asuragen, A Bio-Techne Brand	Indirect evidence	Austin, TX, United StatesHQ checked Sep 14, 2026	51-200	123 contacts →
	Indirect evidence “Asuragen is now part of Bio‑Techne Diagnostics™.” Source: RevenueBase Database · checked Sep 14, 2026

RevenueBase Smart Search

RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: biotech software companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.

Strong evidence: The company's own public description of its business names biotech software companies.
Partial evidence: Its own public description names part of biotech software companies, so it works in or next to the category without describing itself that way.
Indirect evidence: The description shown does not name biotech software companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.

RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.

Showing 25 of 805 biotech software companies based in the United States

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Biotech software companies based in the United States at a glance

As of Sep 14, 2026

41.2%Verified-email coverage

22.8Average contacts per company

1-10Median size (employees)

4.8%Largest-city concentration · San Francisco

Sep 14, 2026Page data refreshed

Companies by employee count

1-10

429

11-50

260

51-200

201-500

501-1,000

1,001-5,000

5,001-10,000

10001+

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 805 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among biotech software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in the United States whose own description of what they do matches “biotech software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search: RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names biotech software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude: Companies whose own description does not clearly place them among biotech software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 7,567 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 14, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Biotech software companies by metro

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names biotech software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many biotech software companies are there based in the United States?

RevenueBase identified 805 biotech software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Caris Life Sciences, headquartered in Irving, tops this list with the largest team on record.

Which city has the most biotech software companies?

San Francisco leads with 39 headquartered companies, followed by San Diego (36) and Boston (30).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 7,567 verified decision-maker contacts tracked across these 805 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 14, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.