Company lists · Data refreshed September 2026
Top 22 AI software developers based in Chicago, United States
RevenueBase identified 70 AI software developers headquartered in Chicago, United States as of September 2026 and tracks 4,313 professional contacts across them, including 2,076 with verified work emails. San Francisco is the largest hub.
This list covers AI software developers headquartered in Chicago, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 27, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 22 largest AI software developers based in Chicago, United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 2,758 contacts → | ||||
Indirect evidence “Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 2 | 685 contacts → | ||||
Partial evidence “At 66degrees, we help companies navigate through the complexities of AI, transforming data into intelligent solutions that empower the modern workforce.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 3 | 366 contacts → | ||||
Strong evidence “SPR is a tech consultancy that builds AI-powered software designed to set businesses apart.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 4 | 158 contacts → | ||||
Partial evidence “We ship AI.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 5 | 46 contacts → | ||||
Indirect evidence “Prenosis is transforming clinical diagnosis with artificial intelligence that leverages holistic molecular and clinical data.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 6 | 29 contacts → | ||||
Indirect evidence “We are a team of data scientists, engineers, and consultants committed to harnessing the vast powers of machine learning to solve distinct problems.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 7 | 23 contacts → | ||||
Partial evidence “Unlock the potential of your data with your own secure AI platform.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 8 | 20 contacts → | ||||
Partial evidence “As part of BridgeWise, the global leader in AI for wealth, Context Analytics powers the unstructured intelligence layer of the world's first vertically integrated, wealth-native…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 9 | 18 contacts → | ||||
Indirect evidence “Launchpad Innovations is all about rethinking how businesses operate.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 10 | 15 contacts → | ||||
Indirect evidence “At Tensor Solutions, we are happy to help you whenever needed, regardless of the time or the moment.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 11 | 13 contacts → | ||||
Strong evidence “End-to-end customized software solutions leveraging Machine Learning to develop AI tools to cater your organizational needs.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 12 | 10 contacts → | ||||
Indirect evidence “At Xaqt, we’re on a mission to Create the New Possible using machine learning-powered products that define new market categories for artificial intelligence and customer…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 13 | 8 contacts → | ||||
Indirect evidence “Since April 2021, Vertical Trail is now part of AHEAD.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 14 | 8 contacts → | ||||
Partial evidence “Welcome to NAKAMOTO: Leading the Charge in AI and ML Innovation At NAKAMOTO, we stand proudly as a trailblazer in AI and ML innovation, reshaping industries with our visionary…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 15 | 4 contacts → | ||||
Partial evidence “We design and build AI-powered systems, applications, and digital experiences that help organizations operate more intelligently and unlock new capabilities.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 16 | 2 contacts → | ||||
Partial evidence “iSimplifyMe is an AI Infrastructure and Orchestration firm.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 17 | 2 contacts → | ||||
Partial evidence “At Greenomix, we build AI to amplify human expertise, not replace it.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 18 | 2 contacts → | ||||
Partial evidence “lyrical AI™ is a general purpose intelligence platform that enables our clients to understand the world better-their products, their customers & employees, and how their business…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 19 | 1 contacts → | ||||
Partial evidence “Quadratyx AI: Your Trusted Partner in Manufacturing Profitability Transformation through AI and Automation.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 20 | 1 contacts → | ||||
Indirect evidence “Financial technology companies sacrifice service, security, and functionality for lower costs.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 21 | 1 contacts → | ||||
Partial evidence “We capture the positive potential of artificial intelligence by developing software solutions focused on empowering humankind.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 22 | 1 contacts → | ||||
Partial evidence “Data Science Partners has a passion for solving challenging problems by applying AI, machine learning, data science and analytics tools as well as years-long experience and…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: AI software developers. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names AI software developers.
- Partial evidence
- Its own public description names part of AI software developers, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name AI software developers. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 22 of 70 AI software developers based in Chicago, United States
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AI software developers based in Chicago, United States at a glance
As of Sep 27, 2026Companies by employee count
Email recency for this list is measured across the whole United States list rather than for Chicago, so it is reported there. Company counts and contact totals on this page are exact for Chicago, over 70 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among AI software developers, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in Chicago, United States whose own description of what they do matches “AI software developers”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names AI software developers), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among AI software developers, and records with no verified work email. Companies headquartered outside Chicago are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 2,076 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 27, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
AI software developers by metro in the United States
- AI software developers in San Francisco276
- AI software developers in New York257
- AI software developers in Austin139
- AI software developers in Los Angeles86
- AI software developers in Dallas74
- AI software developers in Dover72
- AI software developers in Chicago70
- AI software developers in Miami68
- AI software developers in Palo Alto63
- AI software developers in Atlanta62
- AI software developers in Boston60
- AI software developers in Seattle58
- AI software developers in Houston56
- AI software developers in San Jose50
- AI software developers in Sheridan50
- AI software developers in San Diego45
- AI software developers in Wilmington41
- AI software developers in Newark39
- AI software developers in Denver38
- AI software developers in New York City32
- AI software developers in Tampa32
- AI software developers in Las Vegas31
- AI software developers in Washington30
- AI software developers in Irvine27
- AI software developers in Phoenix26
- AI software developers in Santa Clara26
- AI software developers in Cambridge25
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names AI software developers, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many AI software developers are there based in Chicago, United States?
RevenueBase identified 70 AI software developers headquartered in Chicago, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Tempus AI, headquartered in Chicago, tops this list with the largest team on record.
Which city has the most AI software developers?
San Francisco leads with 276 headquartered companies, followed by New York (257) and Austin (139).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 2,076 verified decision-maker contacts tracked across these 70 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 27, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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