Company lists · Data refreshed November 2026

Top 25 Ai-powered helpdesk software companies based in the United States

Name: Ai-powered helpdesk software companies based in the United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Nov 5, 2026 3,998 companies tracked

RevenueBase identified 3,998 company matches for ai-powered helpdesk software companies associated with the United States as of November 2026 and tracks 81,437 professional contacts across them, including 23,130 with verified work emails. San Francisco is the largest hub.

This list covers company matches for ai-powered helpdesk software companies associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed November 5, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Nov 5, 2026 How this list was built

3,998Companies

81,437Contacts tracked

23,130Verified emails

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The 25 largest ai-powered helpdesk software companies based in the United States

Ranked by team size

Top 25 of 3,998 company matches for ai-powered helpdesk software companies based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Nov 5, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#	Company	RevenueBase SmartSearch	Headquarters	Employees	Contacts
1	24 7.ai	Exact match	Campbell, CA, United StatesHQ recorded Nov 5, 2026	10001+	9,332 contacts →
	Exact match “24]7.ai™ customer engagement solutions use conversational artificial intelligence to understand customer intent, enabling companies to create personalized, predictive, and…” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
2	Zendesk	Exact match	San Francisco, CA, United StatesHQ recorded Nov 5, 2026	5,001-10,000	7,195 contacts →
	Exact match “Move beyond deflection.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
3	Compass UOL	Exact match	San Francisco, CA, United StatesHQ recorded Nov 5, 2026	5,001-10,000	4,579 contacts →
	Exact match “We are AI/R.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
4	Teknowledge	Exact match	Colorado Springs, United StatesHQ recorded Nov 5, 2026	1,001-5,000	2,095 contacts →
	Exact match “AI is changing everything.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
5	Nextiva	Exact match	Scottsdale, AZ, United StatesHQ recorded Nov 5, 2026	1,001-5,000	1,642 contacts →
	Exact match “Build amazing customer experiences with Nextiva’s AI-powered platform.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
6	Dialpad	Exact match	San Ramon, CA, United StatesHQ recorded Nov 5, 2026	1,001-5,000	1,563 contacts →
	Exact match “Dialpad is the leading AI-powered communications intelligence platform creating human-first, AI-enhanced solutions that will drive the next wave of how businesses communicate with…” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
7	Crescendo	Exact match	San Francisco, United StatesHQ recorded Nov 5, 2026	1,001-5,000	1,278 contacts →
	Exact match “Crescendo is the AI-Native Customer Experience Platform.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
8	kore.ai	Exact match	San Mateo, CA, United StatesHQ recorded Nov 5, 2026	501-1,000	1,248 contacts →
	Exact match “Kore.ai, a leader in enterprise AI, accelerates business outcomes from AI with agentic AI applications built on the industry-leading Kore.ai Agent Platform.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
9	Airtable	Exact match	San Francisco, TX, United StatesHQ recorded Nov 5, 2026	501-1,000	1,063 contacts →
	Exact match “Airtable’s AI app platform is the easiest way to build custom apps that accelerate your business operations.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
10	Sierra	Exact match	San Francisco, CA, United StatesHQ recorded Nov 5, 2026	201-500	1,036 contacts →
	Exact match “Sierra helps businesses build better, more human customer experiences with AI.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
11	Gupshup	Exact match	San Francisco, CA, United StatesHQ recorded Nov 5, 2026	1,001-5,000	989 contacts →
	Exact match “Gupshup is the leading platform for building and deploying industry-trained Conversational AI Agents for every business across marketing, commerce, and support use cases.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
12	Intercom	Exact match	San Francisco, CA, United StatesHQ recorded Nov 5, 2026	1,001-5,000	848 contacts →
	Exact match “We’re Intercom, the AI customer service company helping businesses deliver incredible customer experiences at scale.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
13	Egain Corporation	Exact match	Sunnyvale, CA, United StatesHQ recorded Nov 5, 2026	501-1,000	802 contacts →
	Exact match “eGain is a leading provider of AI-powered knowledge management and customer experience automation solutions.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
14	yellow.ai	Exact match	San Mateo, CA, United StatesHQ recorded Nov 5, 2026	1,001-5,000	728 contacts →
	Exact match “Yellow.ai powers the future of service with Agentic AI.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
15	Moveworks	Exact match	Mountain View, CA, United StatesHQ recorded Nov 5, 2026	501-1,000	655 contacts →
	Exact match “Moveworks is the AI Assistant platform the world’s foremost organizations trust to empower their entire workforce with AI that gets work done.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
16	OPKEY	Exact match	Pittsburgh, PA, United StatesHQ recorded Nov 5, 2026	201-500	491 contacts →
	Exact match “Unlock millions in IT savings with Opkey, the first end-to-end, AI-native agentic platform that streamlines every step of the enterprise application journey while optimizing…” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
17	Saas Labs	Exact match	Palo Alto, CA, United StatesHQ recorded Nov 5, 2026	201-500	452 contacts →
	Exact match “SaaS Labs is all about helping sales and support teams reach their full potential.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
18	Vsynergize AI	Exact match	Westborough, MA, United StatesHQ recorded Nov 5, 2026	501-1,000	452 contacts →
	Exact match “Vsynergize.ai is your strategic transformation partner, combining AI-driven technology, expert services, and flexible talent solutions to accelerate your business success.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
19	Sensiple	Exact match	Woodbridge, NJ, United StatesHQ recorded Nov 5, 2026	201-500	445 contacts →
	Exact match “Sensiple empowers enterprises with AI-driven, cloud-ready solutions and services that is aimed at streamlining operations, enhancing user experience, and unlocking unmeasurable…” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
20	SPR	Exact match	Chicago, IL, United StatesHQ recorded Nov 5, 2026	201-500	387 contacts →
	Exact match “SPR is a tech consultancy that builds AI-powered software designed to set businesses apart.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
21	Calliduscloud	Exact match	Dublin, CA, United StatesHQ recorded Nov 5, 2026	1,001-5,000	381 contacts →
	Exact match “CallidusCloud is now SAP Sales Cloud, part of the SAP Customer Experience division of SAP.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
22	observe.ai	Exact match	Redwood City, CA, United StatesHQ recorded Nov 5, 2026	201-500	363 contacts →
	Exact match “Observe.AI is the AI Agents platform for customer experience, designed to help organizations deliver faster, smarter, and more efficient customer service at scale.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
23	Polyai	Exact match	San Francisco, CA, United StatesHQ recorded Nov 5, 2026	201-500	345 contacts →
	Exact match “The leading provider of enterprise AI agents for customer service.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
24	Callminer	Exact match	Waltham, MA, United StatesHQ recorded Nov 5, 2026	201-500	338 contacts →
	Exact match “CallMiner is the global leader in AI-powered conversation intelligence and customer experience (CX) automation.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase
25	ASAPP	Exact match	New York, NY, United StatesHQ recorded Nov 5, 2026	201-500	313 contacts →
	Exact match “ASAPP is an artificial intelligence solution provider committed to solving the toughest problems in customer service.” Recorded in the RevenueBase company graph · Nov 5, 2026 · View company records in RevenueBase

RevenueBase SmartSearch

Describe a niche business in your own words. RevenueBase SmartSearch compares the meaning of your description with company business descriptions compiled in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit.

This list uses Exact for “ai-powered helpdesk software companies”. Each Exact match badge shows membership in that saved search; it is not an individual similarity score or a service-quality rating. Recorded descriptions are shown where available.

Showing 25 of 3,998 ai-powered helpdesk software companies based in the United States

See the full list, filter by size, metro and specialty, and access 23,130 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Ai-powered helpdesk software companies based in the United States at a glance

As of Nov 5, 2026

28.4%Verified-email coverage

20.4Average contacts per company

1-10Median size (employees)

7.5%Largest-city concentration · San Francisco

Nov 5, 2026Page data refreshed

Companies by employee count

1-10

2,683

11-50

938

51-200

271

201-500

501-1,000

1,001-5,000

5,001-10,000

10001+

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 3,998 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies: Company records associated with the United States whose business descriptions match “ai-powered helpdesk software companies” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch: Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview: The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality: RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every displayed company carries at least one verified work email. RevenueBase tracks 23,130 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on November 5, 2026. Lists refresh periodically as the graph is re-checked.
Record context: Company records and descriptions can change. Check the company's website for its current services and locations.

Ai-powered helpdesk software companies by metro

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “ai-powered helpdesk software companies”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many ai-powered helpdesk software companies are there based in the United States?

RevenueBase identified 3,998 company matches for ai-powered helpdesk software companies associated with the United States as of November 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

24 7.ai tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most ai-powered helpdesk software companies?

San Francisco leads with 298 company records, followed by New York (272) and Austin (150).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 23,130 professional contacts with verified work emails tracked across these 3,998 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on November 5, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.